Protein Alignment CG3295 and RMND5B

DIOPT Version :9

• Sequence 1: NP_611536.1
• Gene: CG3295 / 37382
• FlyBaseID: FBgn0034573
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: XP_024301936.1
• Gene: RMND5B / 64777
• HGNCID: 26181
• Length: 434
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 171/472 - (36%)
• Similarity: 252/472 - (53%)
• Gaps: 88/472 - (18%)

  Fly     8 CSSVEKDLTRVVSKLEQLHENAEADIGDIATQMSELVEVLSRAEQLVTTLNSSTQVSQDDPMGDA 72
            |:.||::|.:|:.|.....::.|..:.::...:.:|     |||.....|       |..|:...
Human     4 CACVERELDKVLQKFLTYGQHCERSLEELLHYVGQL-----RAELASAAL-------QGTPLSAT 56

  Fly    73 VSMQVETEPTAPQRLTERQVESVRNALARC----HERVQKLSTEHRDLHGSISKIGKAIDR---- 129
            :|:                      .:::|    .:.||||:::|:|:|.|:|::||||||
Human    57 LSL----------------------VMSQCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDRVSTW 99

  Fly   130 -------------------------------------NFSADFSSTMRVDVLQD--EENLMLLNK 155
                                                 ||.::....:. |.:.|  |:...:|..
Human   100 PAPGVGWEHPEAGMYKDSKESQQECPHHQALSLLLRQNFDSEICGVVS-DAVWDAREQQQQILQM 163

  Fly   156 AIAKHYCRQGMDDVARTLIRECKMSPEHAQDVFDSEREFADIYGIWVKIQKRDLTDALKWAKMYS 220
            ||.:|..:|||..||..|.:|..::.:     .|.::.|.::..|...:.::||..||:||..:.
Human   164 AIVEHLYQQGMLSVAEELCQESTLNVD-----LDFKQPFLELNRILEALHEQDLGPALEWAVSHR 223

  Fly   221 QQLSDRHSLIEFRLHRMRFMQLVSYGLDSQREAISYARLNFKKFAVRYEHEIANLMASFIYLPSG 285
            |:|.:.:|.:||:|||:.|::|::.|...|.||:|||| :|:.||..::.||..:|.|.:||..|
Human   224 QRLLELNSSLEFKLHRLHFIRLLAGGPAKQLEALSYAR-HFQPFARLHQREIQVMMGSLVYLRLG 287

  Fly   286 LENSPYKHFLGQEKWTELSFIFLKDACQLLGISKNSALSVVVNAGCTALPALLNIKQVMQSRQVL 350
            ||.|||.|.|....|.|:...|.:|||.|||:|..|.|||...:||.|||.|:|||.|::.||..
Human   288 LEKSPYCHLLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCT 352

  Fly   351 GMWNGCDELPIEIDLQPEFRFHSIFACPILRQQTSEDNPPKKLTCGHVISNDALHKLSVGHILKC 415
            |:||..|||||||:|..:..:||:|||||||||||:.|||.||.||||||.|||:||..|..|||
Human   353 GVWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKC 417

  Fly   416 PYCPVEQNAEEAVRIYF 432
            ||||:|||..:..||.|
Human   418 PYCPMEQNPADGKRIIF 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3295	NP_611536.1	COG5109	88..432	CDD:227440	155/390 (40%)
		LisH	152..181	CDD:128913	11/28 (39%)
		CTLH	193..250	CDD:128914	19/56 (34%)
		CRA	252..343	CDD:214806	46/90 (51%)
		zf-RING_UBOX	377..416	CDD:290181	28/38 (74%)
RMND5B	XP_024301936.1	COG5109	<137..434	CDD:227440	139/303 (46%)
		CLTH	196..340	CDD:371161	62/144 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147969
Domainoid	1	1.000	127	1.000	Domainoid score	I5375
eggNOG	1	0.900	-	-		E1_COG5109
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	313	1.000	Inparanoid score	I2577
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55101
OrthoDB	1	1.010	-	-		D576638at33208
OrthoFinder	1	1.000	-	-		FOG0002102
OrthoInspector	1	1.000	-	-		otm41683
orthoMCL	1	0.900	-	-		OOG6_102297
Panther	1	1.100	-	-	LDO	PTHR12170
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1719
SonicParanoid	1	1.000	-	-		X1554
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800