Protein Alignment CG9346 and U2surp

DIOPT Version :10

• Sequence 1: NP_611535.1
• Gene: CG9346 / 37381
• FlyBaseID: FBgn0034572
• Length: 957
• Species: Drosophila melanogaster
• Sequence 2: NP_001417469.1
• Gene: U2surp / 315903
• RGDID: 1307882
• Length: 1029
• Species: Rattus norvegicus
• Alignment Length: 1038
• Identity: 457/1038 - (44%)
• Similarity: 622/1038 - (59%)
• Gaps: 147/1038 - (14%)

  Fly     2 SKQGNKSKDSAAASATLKRISEKKLEAFTVGTFS--KRQLSKKELEDQKKKEDAAAAAHAFKEFV 64
            ::.|.:|...:......:.:.|.||:||::|..|  ||.|||||.|:.|||||..|||..::||:
  Rat    57 NESGRESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFL 121

  Fly    65 ETFQDAPTPSSKVWVKAGTYDAGSRREDKSEK-GKLYKPVSKLME------KSSSDKVEDYAKTL 122
            ..|:.:.....|.:|:.|..:|.....:..|| ||:|||.|:..:      :||:::.   ...|
  Rat   122 AAFEGSDGNKVKTFVRGGVVNAAKDEHETDEKRGKIYKPSSRFADQKNPPNQSSNERP---PSLL 183

  Fly   123 ASDLKKDSGPLKKKNQEKKKSNLELFKEELRQIQEEREERHKYKHMASSHSAPAQQPAASAAPVP 187
            ..:.||.  ||||..:||||||||||||||:||||||:||||.|...|..     :|..|.:...
  Rat   184 VIETKKP--PLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRF-----EPPQSDSDGQ 241

  Fly   188 SSSVSTTSQNSSSS-----KESGSFDTGDPNTTNLYLGNLNPKISEQQLMEIFGRYGPLASIKIM 247
            ..|:...|:.:.||     ...||.|.|||:||||||||:||:::|:.|.:.|||:|||||:|||
  Rat   242 RRSMDVPSRRNRSSGVLDDYAPGSHDVGDPSTTNLYLGNINPQMNEEMLCQEFGRFGPLASVKIM 306

  Fly   248 WPRSEEEKQRGRNCGFVAYMSRKDAERALKTLNGRYIMGYEMRLGWGKTVPIMNTPIFTPQALLE 312
            |||::||:.|.|||||||:|:|:|||||||.|||:.||.:||:|||||.|||...||:.|.:::|
  Rat   307 WPRTDEERARERNCGFVAFMNRRDAERALKNLNGKMIMSFEMKLGWGKAVPIPPHPIYIPPSMME 371

  Fly   313 MTLPPPPSGLPFNAQP-----PPSEADVLPKKNYKEFNQEDKENMERILAKCVVKVHIPTEKAVL 372
            .|||||||||||||||     .|:...:.|.||        ||:.|:.|::.:|||.||||:.:|
  Rat   372 HTLPPPPSGLPFNAQPRERLKNPNAPMLPPPKN--------KEDFEKTLSQAIVKVVIPTERNLL 428

  Fly   373 NVIHRMIEFVIREGPMFEALIMIREMENPLFAFLFDNESPAHIYYRWKLFSLLQGDTPNEWREEE 437
            .:||||||||:||||||||:||.||:.||:|.|||:|::|||:||||||:|:||||:|.:||.|:
  Rat   429 ALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSILQGDSPTKWRTED 493

  Fly   438 FRMFKNGPVWKPPIANFYTQGMPDE-----LVVDPDAPVVHKGALSNAQRNRLEDLIRHLTPERA 497
            |||||||..|:||..|.|..||.:|     .|.:|.    .||||...||::||:::|.|||.:.
  Rat   494 FRMFKNGSFWRPPPLNPYLHGMSEEQETEAFVEEPS----KKGALKEEQRDKLEEILRGLTPRKN 554

  Fly   498 RIGDAMIFCIEHADAADEICECIAESLSNINTLASKKIARLYLISDILHNCTVKVANASFFRKSV 562
            .|||||:||:.:|:||:||.:||.||||.:.|...||||||||:||:|:|.:.||||||::||..
  Rat   555 DIGDAMVFCLNNAEAAEEIVDCITESLSILKTPLPKKIARLYLVSDVLYNSSAKVANASYYRKFF 619

  Fly   563 EKQLLDIFDNLHNYYLNIESRLKAEGFKSRVCNVIRTWEEWTIYPKDFMAQLTAKFLGKPYVKPV 627
            |.:|..||.:|:..|..|:..|::|.||.||....|.||:|.|||:.|:.:|...|||      :
  Rat   620 ETKLCQIFSDLNATYRTIQGHLQSENFKQRVMTCFRAWEDWAIYPEPFLIKLQNIFLG------L 678

  Fly   628 NNSPQAEETRFDEALDEDIDGAPLSGEEKDDEDLDGVPLDGAALLKSALKRAIPDADAGTPKRDT 692
            .|..:.:||   |.:.:|:||||:      :|:|||.||:              |.| |.|...|
  Rat   679 VNIIEEKET---EDVPDDLDGAPI------EEELDGAPLE--------------DVD-GIPIDAT 719

  Fly   693 PKKDEYLDEIDGIP---LDDDLDGVPLEKETKSTAKLPGF--IPSKWETVDPQQVEAQAITTSKW 752
            |     :|::||:|   ||||||||||:....|....|.|  .|||||.||..::||||:|||||
  Rat   720 P-----IDDLDGVPIKSLDDDLDGVPLDAAEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKW 779

  Fly   753 DTLDPPD--PPKFFSSDDDSGED----------------NP----------QKY---TDEMRQKL 786
            :..|..:  ..:...:.::..||                ||          .||   ::|.|.||
  Rat   780 ELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPVREEMTESKFSKYSEMSEEKRAKL 844

  Fly   787 RDIESKAIQYQDELESGKRRLEPGWSVPEQVEQFRKRLL--------------------KQDSRS 831
            |:||.|.:::|||||||||..:||.|..||||.:|.:||                    |.:|||
  Rat   845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRS 909

  Fly   832 EATVDSPLSYMHIKSKSSKVSESPALFRSSSRKRSHSPFSGGESKRRDYSPETSRSSKSSKRNRS 896
            :...:........|.:..:.|.||:..||||.:|..||     |.:.:.|..:.||.|.|.|:||
  Rat   910 KDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSP-----SPKSERSERSERSHKESSRSRS 969

  Fly   897 RSPSSSPKRYTERSSRS-SRYETP-ASGSSRSRSSPTSSRSSRREEPSPPRHRSDKHKHKHRH 957
             |...||:..::::.|| |...|| .|..|||||...|.:.||.:..||  |||.|...|::|
  Rat   970 -SHKDSPRDASKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSP--HRSHKKSKKNKH 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9346	NP_611535.1	RRM_SR140	214..297	CDD:409670	57/82 (70%)
		Surp	373..423	CDD:460339	36/49 (73%)
		RPR	480..619	CDD:214731	69/138 (50%)
		cwf21_SR140	778..827	CDD:410597	28/71 (39%)
U2surp	NP_001417469.1	None