Protein Alignment CG9346 and sap-140

DIOPT Version :10

• Sequence 1: NP_611535.1
• Gene: CG9346 / 37381
• FlyBaseID: FBgn0034572
• Length: 957
• Species: Drosophila melanogaster
• Sequence 2: NP_498648.1
• Gene: sap-140 / 176063
• WormBaseID: WBGene00015581
• Length: 933
• Species: Caenorhabditis elegans
• Alignment Length: 1015
• Identity: 306/1015 - (30%)
• Similarity: 464/1015 - (45%)
• Gaps: 219/1015 - (21%)

  Fly    34 FSKRQLSKKELEDQKKKEDAAAAAHAFKEFVETFQDAPTPSS--KVW----------VKAG---- 82
            :||::  ||..:|::.|.:     .|..||...|..:.:.||  |.:          :.||
 Worm     5 WSKKR--KKTSDDEEAKLN-----DALLEFQADFGQSSSVSSQPKTFLRGNVVEGNKISAGDGGI 62

  Fly    83 ------------TYDAGSRREDKSEKGKLYKPVSKLMEKSSSDKVEDYAKTLASDLKKDSGPLK- 134
                        |.:.||:..|:::|....|....|.:.:.|.|:.:..|.:....:....|.|
 Worm    63 YAPKFSMNIPSKTSNVGSKDFDEAKKLAAAKARRMLEDVARSKKMTEVPKVVVPTTRPFQRPPKP 127

  Fly   135 ---KKNQEKKK-SNLELFKEELRQIQEEREERHKYKHMASSHSAPAQQPAASAAPVPSSSVSTTS 195
               |..|:|.| |.:|:||.||:::||:||:|...:|........ |......||........||
 Worm   128 GSSKAKQDKPKISQMEMFKMELQRVQEDREKRKDLRHHLEKVGMD-QAVVERLAPTVERGFQGTS 191

  Fly   196 QNSSSSKESGSFDTGDPNTTNLYLGNLNPKISEQQLMEIFGRYGPLASIKIMWPRSEEEKQRGRN 260
            :          || .||.|||:|:.|:...::|..|:..||.:||||::||::||||||::|...
 Worm   192 E----------FD-DDPYTTNVYVSNIPHSVTEDDLLFTFGSFGPLAALKILYPRSEEERRRPHI 245

  Fly   261 CGFVAYMSRKDAERALKTLNGRYIMGYEMRLGWGKTVPIMNTPIFTPQALLEMTLPPPPSGLPFN 325
            |.|||:|||.|.:|.:..:....:....:|..:.:.|.|...|.:.|..|..:..|.|.|.||||
 Worm   246 CAFVAFMSRADVDRFMAEVRVIIVRNEPIRFAFARPVQIPAIPYYIPPVLHALQHPDPTSNLPFN 310

  Fly   326 AQPPPSEADVLPKKNYKEFN------------QEDKENMERILAKCVVKVHIPTEKAVLNVIHRM 378
            |||..::|    ||..:::|            |...|:...::....::|.:|.::.::.|:.||
 Worm   311 AQPDCADA----KKFLEKYNTFPPMHALPTKGQYGYEDFTELIRNSQIRVVVPPDRKLVRVMDRM 371

  Fly   379 IEFVIREGPMFEALIMIREMENPLFAFLFDNESPAHIYYRWKLFSLLQGDTPNEWREEEFRMFKN 443
            ..:|:.|||.|||:|...|.:||:|.||:||.|..|:||||:::|||||||..|||...||||:|
 Worm   372 AVYVVTEGPQFEAMICAEEFQNPMFQFLWDNTSALHVYYRWRIYSLLQGDTIEEWRRTPFRMFEN 436

  Fly   444 GPVWKPPI-ANFYTQGMPDELV------VDPDAPV-VHKGA------------------------ 476
            |..|.||. .|.....||.||.      ..||..: |..|.
 Worm   437 GSWWIPPYPINELRDAMPKELYHMNCLRTYPDKWMKVRDGGQRRGGESSKNRRNSDAEKEERKMR 501

  Fly   477 --------------------LSNAQRNRLEDLIRHLTPERARIGDAMIFCIEHADAADEICECIA 521
                                :|:.:|::||.|||.||||:..|...|::||::|..|.|||||:.
 Worm   502 REEEKERKRREKNEKKRNNRMSDKRRDKLETLIRELTPEKTSIAATMVWCIQNAKYAAEICECVY 566

  Fly   522 ESLSNINTLASKKIARLYLISDILHNCTVK-VANASFFRKSVEKQLLDIFDNLHNYYLNIESRLK 585
            :||:..:....|||:|||||:|||.||..: |.:...:|...|..|..||..:...|..|.||:|
 Worm   567 DSLTIEDIPLYKKISRLYLINDILSNCVQRNVRDVFLYRSHFEALLEKIFVAVGKAYRAIPSRIK 631

  Fly   586 AEGFKSRVCNVIRTWEEWTIYPKDFMAQLTAKFLGKPYVKPVNNSPQAEETRFDEALDEDIDGAP 650
            .|.||.||..|.|.:||..:||.|.:......|||.     :....:..|.|.::.|:
 Worm   632 QEQFKQRVMCVFRNFEEMAVYPTDKLIHNQNVFLGL-----IEIGKEKSEERDNQKLE------- 684

  Fly   651 LSGEEKDDEDLDGVPLDGAALLKSALKRAIPDADAGTPKRDTPKKDEYLDEIDGIPLDDDLDGVP 715
               ||:|:||||||||:                    .::.....:|.|.:      ||.:||:|
 Worm   685 ---EEEDEEDLDGVPLE--------------------EEKSVQNMNESLYD------DDGIDGIP 720

  Fly   716 LEKETK------STAKLPGFIPSKWETVDPQQVEAQAITTSKWD-------TLDPPDPPKFFSSD 767
            |.:|.|      |||       ||::.|:.::.:...|.:||||       ..:..|......:|
 Worm   721 LHEEVKPSTSTYSTA-------SKFKPVESRKRDGSPIFSSKWDHDGRKSNEEEDEDIDGVMITD 778

  Fly   768 DDSGE-------------DNPQKYT-----DEMRQKL-RDIESKAIQYQDELESGKRRLEPGWSV 813
            |.:.|             |....:|     ||.|:|| ||:|.:||...|:||:.:   :|  ..
 Worm   779 DTTSENLQRDSLSPGEIKDKESSFTVLTPSDEKRRKLIRDVEVRAIAMLDDLEADR---DP--DA 838

  Fly   814 PEQVEQFRKRLLKQDSRSEATVDSPLSYMHIKSKSSKVSESPALFRSSSRKRSHSPFSGGESKRR 878
            ..:|::||:..:::..::..:.:|..|    ..||.:.||.....|...||||       .|:.|
 Worm   839 KRKVDEFRRCEMEKVEKALRSGESKKS----DEKSERKSEKKEKKRDKERKRS-------RSRSR 892

  Fly   879 DYSPETSRSSKSSKRNRSRS-PSSSPKRYTERS-SRSSRY 916
            |...:.||..:|..|:|.|. .....:|..:|. .|..||
 Worm   893 DRDRDRSRRDRSRDRSRDRDRDRDRDRRDRDRDRDRDRRY 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9346	NP_611535.1	RRM_SR140	214..297	CDD:409670	32/82 (39%)
		Surp	373..423	CDD:460339	25/49 (51%)
		RPR	480..619	CDD:214731	59/139 (42%)
		cwf21_SR140	778..827	CDD:410597	18/54 (33%)
sap-140	NP_498648.1	RRM_SR140	199..282	CDD:409670	32/82 (39%)
		Surp	366..416	CDD:460339	25/49 (51%)
		VHS_ENTH_ANTH	529..665	CDD:470608	58/135 (43%)