DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10543 and CG1024

DIOPT Version :9

Sequence 1:	NP_001369100.1	Gene:	CG10543 / 37379	FlyBaseID:	FBgn0034570	Length:	1666	Species:	Drosophila melanogaster
Sequence 2:	NP_001138014.2	Gene:	CG1024 / 40789	FlyBaseID:	FBgn0027514	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	88/466 - (18%)
Similarity:	141/466 - (30%)	Gaps:	196/466 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   609 HQRQMMMMPEDFPQHGASMMNSRQMPALAA--LSNLGDTPAMS--GQLNSSLELDDNDLSADE-D 668
            |.|::    |.:......|...:..|..||  ..|.....|:.  |:...|.....|||.... .
  Fly   127 HMREI----EKYENKLRQMKRQQAKPTTAAAPAGNAEKPMAVKPRGRPKGSTNRKQNDLLQKALM 187

  Fly   669 DDDLDHDLDELDAAKQQLIDGGSSSSTSLQAPPSQHGSGSGGSGGQTPGSKKDKPSYNCLLCPKS 733
            |.||:.::::             |..|:|.||.::            |....:....|...|..:
  Fly   188 DIDLNTEMEK-------------SPVTALAAPVNE------------PKPISNVSELNLDRCLNA 227

  Fly   734 Y-----RKRKSLLDHYKMHPGYCHDCGQRNGNTLEEIIHHNRTMHVKEF----PFVCETCGESYS 789
            |     ::.|.::..|              .:.|:.:        .|||    |...:  ||:..
  Fly   228 YEDIVRKEEKEVVPKY--------------DDELDAL--------CKEFFDDGPSAGK--GEANE 268

  Fly   790 RKQQFHAHVESHN-------------------KKEIKTFPCGECGLKFPQKKLQ-----QHFEET 830
            .:||..||::..|                   |||:|:.|..:     |.|:.:     ....:|
  Fly   269 EQQQDDAHLQQGNQEVVIIEIDALGKEEVAQLKKEMKSDPISQ-----PTKRRRISTTPSRDSDT 328

  Fly   831 GHKADGA------ICEVCGEEFQSKNALYQHIIRVHKRDNFFECHICHNRF-------------- 875
            ....:|.      :|..||:|..|.:....|:.:.|.    || ||..|.|
  Fly   329 EMSTNGLTKLISYLCPKCGKEIASMDGWRAHVFKKHD----FE-HIIENSFKILESGRKAMCLQC 388

  Fly   876 ------TLKANLERHVQLHTEIKRPYVCDLCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFG 934
                  |:::.|::|...|.    ||      .||.                   |||||.:...
  Fly   389 REVQPTTVRSQLQKHCFKHL----PY------RSYL-------------------KCTLCDRTKT 424

  Fly   935 SAKSLQRHLP-SHSEE-----------RPH----------------------------CCNYCDQ 959
            |...:..|:. :|.||           :|.                            .|.:||:
  Fly   425 STSKILNHIRYNHQEELQRKNKTQLLIKPEPMWASPNKSGQAAMADDAGSEDDQGEQAVCEHCDR 489

  Fly   960 TFKWKTHLVRH 970
            .|:.|....||
  Fly   490 VFRSKWRYERH 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368	4/24 (17%)
		C2H2 Zn finger	751..773	CDD:275368	1/21 (5%)
		C2H2 Zn finger	781..801	CDD:275368	6/19 (32%)
		PHA00733	<804..860	CDD:177301	14/66 (21%)
		C2H2 Zn finger	811..827	CDD:275368	2/20 (10%)
		C2H2 Zn finger	839..860	CDD:275368	6/20 (30%)
		C2H2 Zn finger	868..888	CDD:275368	7/39 (18%)
		C2H2 Zn finger	897..913	CDD:275368	2/15 (13%)
		C2H2 Zn finger	926..946	CDD:275368	6/20 (30%)
		C2H2 Zn finger	954..975	CDD:275368	7/17 (41%)
CG1024	NP_001138014.2	C2H2 Zn finger	30..51	CDD:275368
		C2H2 Zn finger	73..100	CDD:275368
		C2H2 Zn finger	106..123	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100