DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10543 and CG10654

DIOPT Version :9

Sequence 1:	NP_001369100.1	Gene:	CG10543 / 37379	FlyBaseID:	FBgn0034570	Length:	1666	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	73/269 - (27%)
Similarity:	108/269 - (40%)	Gaps:	45/269 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   729 LCPKSYRKRKSLLDHYKMHPGYCHDCGQRNGNTLEEIIHHNRTMHVKEFPFVCETCGESYSRKQQ 793
            :|.:|.|..:.||....:.   ||        .||:     .|.|..:.|   ....||.:.:.|
  Fly   104 MCAESLRNFEKLLQDIDIG---CH--------KLED-----HTWHDLDTP---SESNESTNPEAQ 149

  Fly   794 FHAHVESHNKKEIKTF----PCGECGLKFPQKKLQQHFEETGHK-ADGAICEVCGEEFQSKNALY 853
            .||...:.. :||.:|    .|....:...:..|....||..:. .|.:..:..|:|   |.::.
  Fly   150 SHAPCIAAT-QEIVSFIWPQVCLPLAVILSRITLGASLEEEVYVIEDESAKQDLGQE---KLSIS 210

  Fly   854 QHIIRVHKR---DNFFECHICHNRFTLKANLERHVQLHTEIKRPYVCDLCGSSYFTYPALKEHYS 915
            ..::...||   .:..||.|||..|...:.||.|:|.| |..|||.|..|..||.....|:.|..
  Fly   211 SKLLGARKRRGVRHTLECRICHRGFYKPSLLEAHMQQH-EGLRPYTCVHCAKSYARANLLESHLR 274

  Fly   916 NAHVDVSECK----CTLCGKRFGSAKSLQRHLPS-----HSEERP---HCCNYCDQTFKWKTHLV 968
            ..|.:....:    |..|.|.:.:.:||:.|:..     |..|.|   |.|..|.:.|..|.||.
  Fly   275 QMHNNADAARIIYACPSCNKVYTANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLT 339

  Fly   969 RHKQTMHGN 977
            |||. :||:
  Fly   340 RHKM-VHGS 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368	5/17 (29%)
		C2H2 Zn finger	751..773	CDD:275368	5/21 (24%)
		C2H2 Zn finger	781..801	CDD:275368	5/19 (26%)
		PHA00733	<804..860	CDD:177301	11/60 (18%)
		C2H2 Zn finger	811..827	CDD:275368	2/15 (13%)
		C2H2 Zn finger	839..860	CDD:275368	3/20 (15%)
		C2H2 Zn finger	868..888	CDD:275368	9/19 (47%)
		C2H2 Zn finger	897..913	CDD:275368	5/15 (33%)
		C2H2 Zn finger	926..946	CDD:275368	6/24 (25%)
		C2H2 Zn finger	954..975	CDD:275368	9/20 (45%)
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	3/10 (30%)
		C2H2 Zn finger	228..248	CDD:275368	9/19 (47%)
		C2H2 Zn finger	256..313	CDD:275368	13/56 (23%)
		C2H2 Zn finger	289..314	CDD:275368	6/24 (25%)
		zf-C2H2	323..345	CDD:278523	10/22 (45%)
		C2H2 Zn finger	325..345	CDD:275368	9/20 (45%)
		C2H2 Zn finger	355..376	CDD:275368
		C2H2 Zn finger	385..405	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010