DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10543 and zf30C

DIOPT Version :9

Sequence 1:	NP_001369100.1	Gene:	CG10543 / 37379	FlyBaseID:	FBgn0034570	Length:	1666	Species:	Drosophila melanogaster
Sequence 2:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	86/374 - (22%)
Similarity:	133/374 - (35%)	Gaps:	95/374 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   718 SKKDKPSYNCLLCPKSYRKRKSLLDHYKMH----------PGYCHDCGQRNGN----TLEEIIHH 768
            :|.|:..:.|.:|.|.|...|.|:.|.|:|          |.||        |    |.|:...|
  Fly   444 AKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYC--------NLFFATKEQATEH 500

  Fly   769 NRTMHVKEFPFVCETCGESYSRKQQFHAHVES-HNKKEIKTFPCGECGLKFPQKKLQQHFEETGH 832
            .|..| ||..: ||.|.:..:.......|..: |:|||.::          .|:.|
  Fly   501 ARAQH-KELLY-CEKCDKYMTGHDSLKNHERNFHSKKEPRS----------QQRNL--------- 544

  Fly   833 KADGAICEVCGEEFQSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEIKRPYVC 897
                 ||:.||::|..:.:|..|:.....|...:.|.:|....:....|:.|:.|| :...||.|
  Fly   545 -----ICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTAGILKTHMLLH-KADTPYQC 603

  Fly   898 DLCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNYCDQTFK 962
            |.||.::......|.|....|.|....||.||.|.:...:||..|:..|:..:...||.|.:.|.
  Fly   604 DKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFT 668

  Fly   963 WKTHLVRHKQTMHGNEPPPPKKGKQRFPKTSEEDMGSLPDMPGPPPVKASKKAATSKAKAQAAAA 1027
            ..::|..|:                   |...:..|.|     |...||::.....:.|....|.
  Fly   669 CISNLQAHR-------------------KVHADTCGQL-----PLNAKATQYMGVQRGKLLMGAK 709

  Fly  1028 AAAAASSQQQQ---------------------QKGSAATPTPPPPVSTT 1055
            ..|....::.:                     ..|||...|.|...::|
  Fly   710 PEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYAST 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368	8/19 (42%)
		C2H2 Zn finger	751..773	CDD:275368	6/25 (24%)
		C2H2 Zn finger	781..801	CDD:275368	4/20 (20%)
		PHA00733	<804..860	CDD:177301	11/55 (20%)
		C2H2 Zn finger	811..827	CDD:275368	2/15 (13%)
		C2H2 Zn finger	839..860	CDD:275368	6/20 (30%)
		C2H2 Zn finger	868..888	CDD:275368	4/19 (21%)
		C2H2 Zn finger	897..913	CDD:275368	5/15 (33%)
		C2H2 Zn finger	926..946	CDD:275368	7/19 (37%)
		C2H2 Zn finger	954..975	CDD:275368	6/20 (30%)
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368
		C2H2 Zn finger	98..117	CDD:275368
		C2H2 Zn finger	134..152	CDD:275368
		C2H2 Zn finger	511..532	CDD:275370	4/20 (20%)
		COG5048	<523..>672	CDD:227381	44/173 (25%)
		C2H2 Zn finger	546..566	CDD:275368	6/19 (32%)
		C2H2 Zn finger	575..595	CDD:275368	4/19 (21%)
		C2H2 Zn finger	603..624	CDD:275368	6/20 (30%)
		C2H2 Zn finger	632..652	CDD:275368	7/19 (37%)
		C2H2 Zn finger	660..680	CDD:275368	7/38 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100