Protein Alignment CG10543 and LOC3289903

DIOPT Version :10

• Sequence 1: NP_001369100.1
• Gene: CG10543 / 37379
• FlyBaseID: FBgn0034570
• Length: 1666
• Species: Drosophila melanogaster
• Sequence 2: XP_558523.4
• Gene: LOC3289903 / 3289903
• VectorBaseID: AGAMI1_015006
• Length: 1965
• Species: Anopheles gambiae
• Alignment Length: 2018
• Identity: 426/2018 - (21%)
• Similarity: 601/2018 - (29%)
• Gaps: 968/2018 - (47%)

  Fly   441 AGAGSMNSASGHSSNSSSSGSGSAGNGNGISGVILENNSHHTHHLSSSSSANLVINGLTS--SNS 503
            |...|::.|:||::.||..|.        |:|                 .|.|.|:..||  ...
Mosquito    87 ASGSSLSVATGHTTVSSFGGD--------IAG-----------------KACLDIDTSTSVRCTD 126

  Fly   504 ISNNNNNSNNVSLHRPQLTPQAQNQLAASMKPS---DHIPISMPME---------NMDLKAGQAA 556
            :|..::....:..||.:..|.|...|...:...   |.:|::..:.         ...|||||.|
Mosquito   127 LSLGSDGLLLMHPHRTREPPLAPWDLRGKLLRGNLFDGLPLTGSVRLGPEYSSRGGTLLKAGQRA 191

  Fly   557 HGTANAIMQGGSSSLASQLHQQQKPYNSSNNPLSMMGGMMQQQQQQHVAMPHHQRQMMMMPEDFP 621
             |:||..:  |:..:...|.:.     .:|:...::..|.:|.......:..::|..:
Mosquito   192 -GSANRWL--GNVRMNRALVRM-----IANHDFKLLFNMFEQSIFPAWKIYKNERIFV------- 241

  Fly   622 QHGASMMNSRQMPALAALSNLGDTPAM---SGQLNSS----LELDDNDLSA-------------- 665
                     |:.|||..::.....||:   ||..:|.    ::.::.|...
Mosquito   242 ---------RKRPALTTVTVRTSLPAICYGSGSSHSPPATYIKKEEFDFDTPYSIADDHCFEEIK 297

  Fly   666 DEDDDDL-----DHDLDELDAAKQQLIDGGSSSSTSLQAPPSQHGSGSGGSGGQTPGSKKDKPSY 725
            ||||:||     |..:|..:....:  :..|:::|||......:...:..|...:....|:: .|
Mosquito   298 DEDDEDLLLMKEDDSIDNSNEIFSE--EESSTNNTSLMLSSDTNTLDTNDSSMVSHERNKEQ-VY 359

  Fly   726 NCLLCPKSYRKRKSLLDHYKMHPGYCHDCGQRNGNTLEEIIHHNRTMHVKEFPFVCETCGESYSR 790
            .||||.|||||||||:.|:..|||:|.|||::.|.|.|||:.|||..| |..|.:||.|||:::|
Mosquito   360 QCLLCDKSYRKRKSLVIHFSHHPGFCPDCGKQRGVTSEEIVEHNRIYH-KNRPHICEHCGETFTR 423

  Fly   791 KQQFHAHVESH----------NKKEIKTFPCGECGLKF-PQKKLQQHFEETGHKADGAICEVCGE 844
            .||:..||:.|          |.|:...:.|..||:.| .||.|::|.::|.|:|:|.:|::||.
Mosquito   424 NQQYQIHVQGHFISKDRVAEQNCKKTHKYSCKTCGIVFNNQKYLEKHIQKTNHQAEGLVCDICGA 488

  Fly   845 EFQSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLH-TEI-KRPYVCDLCGSSYFTY 907
            .|.:...|.||:.|.|           ||.||.||.|||.:.|. |.: .:.:.|:.||:|:.:.
Mosquito   489 IFCNSIKLSQHVSRTH-----------HNVFTQKATLERSLLLQGTSVTDKAFTCEQCGASFLSQ 542

  Fly   908 PALKEHYSNAH-VDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNY--CDQTFKWKTHLVR 969
            |:|:||...:| |..::.:|.:|.|.|.:.:||:||...||:||...|..  |.:::|.::||.|
Mosquito   543 PSLREHIKLSHSVPENKFECNICNKLFAAKRSLKRHKLCHSDERAFRCTVENCKESYKNQSHLAR 607

  Fly   970 HKQTMHGNEPPPPKKGKQRFPKTSEEDMGSLPDMPGPPPVKASKKAATSKAKAQAAAAAAAAA-- 1032
            |.:|.|..:||                               ||:...:||.|.|||||||.|
Mosquito   608 HMKTAHHIDPP-------------------------------SKRLQKAKAAAAAAAAAAAGAGT 641

  Fly  1033 --------------------------------------SSQQQQQKGSA---------------- 1043
                                                  ||..::..||:
Mosquito   642 STATASSADPSSASTDFITHGDVATMGGGSCDSLKGMGSSTLKKSLGSSEKSLGDSSTNFSDNLS 706

  Fly  1044 -------------ATPTPPPPVSTT------PGCLQQDPFNAAMVSSNSS---------QSSTAS 1080
                         :||.....:.||      ||.|  .|.::|:.....|         |.|:.:
Mosquito   707 SFNYEFSDTTAGTSTPALAAAMGTTGSDGSVPGAL--TPSSSALAGQRPSALTCSVTGIQQSSGT 769

  Fly  1081 TSQHSVS-TSESQQNSIYNQSFNAEKQQPGQQQPQNTLHQQHPTPPPPQQQQQQQQQQQ------ 1138
            .:..::| .:..||.|:..|....::||..|||.|....||.......|||||||||||
Mosquito   770 FNDPAISFGTNKQQQSLQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQLQQQ 834

  Fly  1139 -------------------------------ALPQSRVG------------------PGELHLQR 1154
                                           |||.|.||                  .|..|||.
Mosquito   835 QLQHQQQPQHLGGGWQNLEFGAGTATAHRSAALPGSVVGGMQPLQDPLAATTGSFMDGGHHHLQN 899

  Fly  1155 ------------------------MNSF------------------------------------- 1158
                                    ..||
Mosquito   900 HQNLQHPTAHHHGLGPMANPMASTAGSFMGSGSLAGGTRRFPLPEGNFMCEHCDETNFINAQQYH 964

  Fly  1159 --------GQDGQFH---------------------------------------------FES-- 1168
                    .:||:.|                                             |.|
Mosquito   965 LHVQDHFAAKDGKDHPSKKLLRLNCKTCNLVFATGAQLDRHIHKTNHHTESIACEICSAIFNSNL 1029

  Fly  1169 ----------------------------------------------------------------- 1168
                                                                             
Mosquito  1030 KVYQHMLKCHKNDVWFACEQCSKVFILKQDYDKHQLVHQTVTDRSIICEHCASSFLTQEALKEHI 1094

  Fly  1169 ----------------------------------------------------------------- 1168
                                                                             
Mosquito  1095 KIAHSMDKKYKCNICNKLFAARRSLKRHKLCHEEEAAFRCPIDGCKEAFRTAANLAKHKKMAHPA 1159

  Fly  1169 ----------------------------------------------------------------- 1168
                                                                             
Mosquito  1160 GLSTVPVPVGNVLAHEPMADKVVAGIGMPGGVKLLPGTMASGTSNAPGGSGALKGMEKAMHHPDP 1224

  Fly  1169 ----------------------------NPAAGA------------------------------- 1174
                                        |||||.
Mosquito  1225 LPGVTMPAGGQPNVMGQMGGSNPMMAMGNPAAGLKTDGRSSAGGMMVVPPSRTSSAGSSTGMSGI 1289

  Fly  1175 --------------------------------------------YQQHQLISQYQQQQQQQQQQQ 1195
                                                        :.||.|  |.|||||||||||
Mosquito  1290 NNGSGGANIPYNPYDASGLNYNSVLGPPGAGVVASSGPHHPHHHHHQHHL--QQQQQQQQQQQQQ 1352

  Fly  1196 QQQPQQQQ--------------QHHLAQ------------------------------QQQ---- 1212
            ||||.|||              .||.||                              :||
Mosquito  1353 QQQPTQQQSQAQLVQHHSQAHAHHHAAQAQFIGMGNPGSSAGLHYSGRSGATASAANPEQQSVSM 1417

  Fly  1213 ------------------------------------QHMRSHTPQSPHP---------PHPSQ-- 1230
                                                |.|...||.:..|         |..:.
Mosquito  1418 AYRMGDTAVPGTSGTASGNATNIPYGYGQMNNAFDWQSMEMGTPTNAEPGLISGSAGQPQAASGS 1482

  Fly  1231 --LQQQQPQQHFSSPHH------------------MPPMHHQHQLMMQQQHRHNQRSPLHHHPAA 1275
              ::.....:::::.|.                  :.|...||     |...|.|:...|.|...
Mosquito  1483 GTMKSATANKYYNAMHEPGSAGSPGVGGGNTTAGFLSPQQLQH-----QSPHHAQQHLQHQHAQQ 1542

  Fly  1276 QQLQQQHQQPSHSPQH-QHARLQSPQPAPVQQQ--QQQQQQQQQQQQQFLQQQAADTWGNMNFGN 1337
            .|||||.|| .|.|.| .||::...|...||:|  .|||||||||||..:...:.:..|..:..|
Mosquito  1543 SQLQQQQQQ-QHLPHHSHHAQVAGLQNKSVQEQHTHQQQQQQQQQQQHMMNMNSQEMMGYQDMWN 1606

  Fly  1338 PPNNQQVELKD-----NKFYIVESAEFLGLPMN----VPPSPQQQQQQAVSKPQQQQQQQ----- 1388
             .|..::|.:|     |....|.:...||..:|    :..|....:||...:.|.|||||
Mosquito  1607 -ANMMKMEFQDEGSGANTGSTVGAYNSLGNILNNLEMMGSSNSSFEQQQTQQQQSQQQQQGYEMV 1670

  Fly  1389 ---------HPQPQQPDPTLAGDLMSFQHMWPAPGFSQTSQQQQPQQQQQQQAAQQQQQAQSQAN 1444
                     |||.:.         .|.|.  ||....|....|..|||||||..||..|.|.|.:
Mosquito  1671 STPRTSSDTHPQSRG---------QSAQS--PALTSQQVQHHQHHQQQQQQQHQQQLHQQQQQPH 1724

  Fly  1445 SSDPHNYNNIGSILTNLIDTNPAPMEYNFDLMQQQQTPS--------------------AQQQQQ 1489
            :...|                          ..:||.||                    .||.||
Mosquito  1725 AKGTH--------------------------FHKQQHPSHSHAQMLPGVEPGQMVNQHHHQQHQQ 1763

  Fly  1490 QQQQQQAAQQQHHSA-----GAYGSGLMRSGGGV-YGGAYEQHLSDQLVSEQQKQNSFQPYHPHG 1548
            ||||||.....||.|     .::.:|.|....|: :|....||....  |.||..:...|:|.|.
Mosquito  1764 QQQQQQQYFSDHHGAHQQVPHSHHTGTMGHSMGIPHGHGQMQHSHGH--SAQQTPSPHHPHHQHH 1826

  Fly  1549 LQAQQQQ----------PLHP-----HPHLLPPPAPHNNVYDRTGVGVGVGVGVGVGVGVGYPML 1598
            ||.||||          |.||     |||   .|.|...|...:|.|.|.|.|..:..|
Mosquito  1827 LQQQQQQQMQQQYNAHLPHHPQMMQHHPH---APGPPGQVPSGSGGGGGGGGGSSLSGG------ 1882

  Fly  1599 GDDTKSVLPPMMGGM-----MQQMPPHGQQPDLIYYPVKNDXQSKQHQQ------------AQQP 1646
            |....:...|...|:     .||.||  |||.:.:.|.:|   :..|..            |:.|
Mosquito  1883 GPTHMAHHNPAHAGVPGQQQQQQQPP--QQPGMSFNPSQN---AADHANAGANPSALPTDIAKTP 1942

  Fly  1647 NHL 1649
            |:|
Mosquito  1943 NNL 1945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368	14/19 (74%)
		C2H2 Zn finger	751..773	CDD:275368	12/21 (57%)
		C2H2 Zn finger	781..801	CDD:275368	10/19 (53%)
		PHA00733	<804..860	CDD:177301	21/56 (38%)
		C2H2 Zn finger	811..827	CDD:275368	7/16 (44%)
		C2H2 Zn finger	839..860	CDD:275368	8/20 (40%)
		C2H2 Zn finger	868..888	CDD:275368	9/19 (47%)
		C2H2 Zn finger	897..913	CDD:275368	6/15 (40%)
		C2H2 Zn finger	926..946	CDD:275368	8/19 (42%)
		KREPA	<944..>1009	CDD:483960	15/66 (23%)
		C2H2 Zn finger	954..975	CDD:275368	8/22 (36%)
LOC3289903	XP_558523.4	None