DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10543 and unc-98

DIOPT Version :9

Sequence 1:	NP_001369100.1	Gene:	CG10543 / 37379	FlyBaseID:	FBgn0034570	Length:	1666	Species:	Drosophila melanogaster
Sequence 2:	NP_509284.2	Gene:	unc-98 / 181020	WormBaseID:	WBGene00006827	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	388	Identity:	77/388 - (19%)
Similarity:	124/388 - (31%)	Gaps:	140/388 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   660 DNDL--SADEDDDDLDHDLDELDAAKQQL-------------IDGGSS----------------- 692
            |:|:  .|.::.||.:..::..|.||..:             |:|.||
Worm     2 DDDIFKEARKERDDFEELMNACDLAKMSVKNNEMVHGLETFGINGESSENGNKEKPKEIMKVVAP 66

  Fly   693 ------SSTSLQAPPSQHGSGSGGSGGQ------TPGSKKDK--PSYNCLLCPKSYRKRKSLLDH 743
                  .|:|.|.|....|....||..|      |...|.|.  ..|.|..|..::....:|..|
Worm    67 TVEAYVGSSSAQTPTKSSGGALDGSDQQEVRQDGTSVQKDDNGFVFYKCRFCGLTFNFMNTLRAH 131

  Fly   744 YKMHPGYCHDCGQRNGNTLEEIIHHNRTMHVKEFPFVCETCGESYSRKQQFHAHVESHNKKEIKT 808
            .::     ||..|                     |:||..||:|:....|...|...|:  ||..
Worm   132 ERI-----HDVSQ---------------------PYVCGKCGDSFEFACQLEYHAAQHS--EIDG 168

  Fly   809 FPCGECGLKFPQKKLQQHFEETGHKADGAICEVCG-EEFQSKNALYQHIIRVHKRDNFFECHICH 872
            :.| |||..|     ..:.|...||......|:.| .|..:.....:.::.|.::|      :..
Worm   169 YKC-ECGRTF-----FSYTEMLYHKHTDDPLELIGAPETTTIKVSKKRVLPVSEQD------LPQ 221

  Fly   873 NRFTLKANLERH-VQLHTEIK-RPYVCDLCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFGS 935
            ..|..:....:| ::::.::: :||:|:.|..||                             ..
Worm   222 PAFVTEGYEPKHPLRVYNDVRSKPYICEYCSKSY-----------------------------SD 257

  Fly   936 AKSLQRHLPSHSEER---PHCCNYCDQTFKWKTHLVRHKQTMHGNEPP--PPKKGKQRFPKTS 993
            ::.|..|:.||..|:   |....|                 |.|.|..  ...:....||:||
Worm   258 SRGLAYHMYSHRGEKYFNPRASRY-----------------MMGREGVGYTDSRSYYLFPRTS 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368	4/19 (21%)
		C2H2 Zn finger	751..773	CDD:275368	3/21 (14%)
		C2H2 Zn finger	781..801	CDD:275368	6/19 (32%)
		PHA00733	<804..860	CDD:177301	13/56 (23%)
		C2H2 Zn finger	811..827	CDD:275368	5/15 (33%)
		C2H2 Zn finger	839..860	CDD:275368	3/21 (14%)
		C2H2 Zn finger	868..888	CDD:275368	2/20 (10%)
		C2H2 Zn finger	897..913	CDD:275368	4/15 (27%)
		C2H2 Zn finger	926..946	CDD:275368	2/19 (11%)
		C2H2 Zn finger	954..975	CDD:275368	1/20 (5%)
unc-98	NP_509284.2	C2H2 Zn finger	115..135	CDD:275368	4/24 (17%)
		C2H2 Zn finger	143..163	CDD:275368	6/19 (32%)
		SFP1	<169..268	CDD:227516	23/139 (17%)
		C2H2 Zn finger	171..189	CDD:275368	8/23 (35%)
		C2H2 Zn finger	248..268	CDD:275368	6/48 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100