Protein Alignment CG10543 and spr-4

DIOPT Version :10

• Sequence 1: NP_001369100.1
• Gene: CG10543 / 37379
• FlyBaseID: FBgn0034570
• Length: 1666
• Species: Drosophila melanogaster
• Sequence 2: NP_001020993.1
• Gene: spr-4 / 172596
• WormBaseID: WBGene00005009
• Length: 1311
• Species: Caenorhabditis elegans
• Alignment Length: 1281
• Identity: 211/1281 - (16%)
• Similarity: 370/1281 - (28%)
• Gaps: 495/1281 - (38%)

  Fly   475 LENNSHHTHHL------SSSSSAN---------------LVINGLTSSNSISNNNNNSNNVSLHR 518
            :||:..|..|.      |.||.||               |.....::..|::::||      :|
 Worm   106 IENSGPHACHKCPSRYESKSSLANHTKMHLGEKRKFACELCDFSASTLKSLTHHNN------IH- 163

  Fly   519 PQLTPQAQNQLAASMKPSDHIPISMPMENMDLKAGQAAHGTANAIMQGGSSSLASQLHQQQKPYN 583
                   ||....|.:.|..||::               .:|::.:....:|...|::....|..
 Worm   164 -------QNFGVLSQQTSPVIPVA---------------SSADSTLNSSINSTGCQINAPPAPKL 206

  Fly   584 SSNNPLSMMGGMMQQQ-------------QQQHVAMPHHQRQMMMMPEDFP----QHGASMMNSR 631
            ....|:::...::..:             :::....|...|:..:...:.|    |....|...|
 Worm   207 DEEAPIAVESVVVHHEDVAEFDTTPPPILEREDDGPPVLIREAPVRKSNRPMKPTQKAQKMTKQR 271

  Fly   632 QMPALAALSNLGDTPAMSGQLNSSL-------ELDDNDLSADEDDDDLDHDLDELDAAKQQLIDG 689
            :..:....|..|..|:.|.   ||:       :::...:.......:|...: ::...:|:....
 Worm   272 ERKSKTVESPKGSLPSSSA---SSVTPPPVRKDVEKPKIFVKTTKKNLKKTM-KITKVRQRCPHC 332

  Fly   690 GSSSSTSLQAPPSQHGSGSGGSGGQTPGSKKDKPSYNC-LLCPKSYRKRKSLLDHYKMH------ 747
            ..::||..:.  ::|      |||.........||.|| .:|    ||...|..||.:|
 Worm   333 PFTTSTVTRL--NRH------SGGHKLKEGYICPSENCNFMC----RKAGFLQKHYILHKGTLPW 385

  Fly   748 -PGYCHDCG----------------------------QRNGNTLEE------------------- 764
             |.|....|                            :|..||::.
 Worm   386 PPEYVKKGGAKMKRTFPESEEKKIEVTEKVQKMKKMHKRRANTVQVVAKAQLKSYIKVEVDDVIF 450

  Fly   765 ------------------IIHHNRTMHVK-EFP---FVCETCG---ESYS--RKQQFHAHVESHN 802
                              |:|..:|...| .||   |:|.|||   :||:  |..:...|..:|
 Worm   451 KKCNIGECEFLTQTLTQLIVHKVKTHDTKTAFPQHRFLCLTCGHRAKSYAALRTHKLIEHTSTH- 514

  Fly   803 KKEIKTFPCGEC-GLKFPQK----KLQQHFEETGHKADG-----------------------AI- 838
            |:..:|:...|| |.||..|    |:|:..:|...:|||                       ||
 Worm   515 KRFHRTYYLKECVGDKFFVKYNLSKVQEEVKEEPKEADGDESGDESFDSMCPASDVHPETLAAIE 579

  Fly   839 -------CEVCGEEFQSKNALYQHIIRVHKRDNFFECHIC------------HNRF--------- 875
                   |.:|..:..:.|...:|..:..|.|. |:|..|            |.:.
 Worm   580 MKDVFFCCNMCPYKAPTMNRCQRHYDKHFKNDE-FKCQYCSWSSRSKEVIVNHEKLHPTVVVANT 643

  Fly   876 ----TLKANLERHVQ-LHTEIKRPYVCD-----------LCGSSYFTYPALKEHYSNAHVD---- 920
                .:|..:|..|: |...:..|..|.           .|......:|.|.|.::...:|
 Worm   644 NEAPVVKNEIEAKVEVLSKTVSSPVECTEESSLSKSIQLWCQREKLRHPELDEQFTRKMIDGVKG 708

  Fly   921 --VSEC-----------------------KCTLCGKRFGSAKSLQRHLPSHS------------- 947
              .::|                       :|..|........||:.||..|:
 Worm   709 FQCTDCPYTSKYRGDMRSHKKRHDIEQLYRCVQCTYTTNRPVSLKDHLKQHAIVNMSIADIKSRR 773

  Fly   948 ----------------EERPHCCNYCDQT-----FKWKTHLVRHKQT------------------ 973
                            :::.:||:.|...     ..|:.|. .|:.|
 Worm   774 VVVNQGVKIGMRRGVGKDKIYCCDKCPYVTLALGCLWRHHR-NHRDTAKINICSNCSYSSIDQRK 837

  Fly   974 ----------MHGNEPPP-----PKKGKQRFPKTSEEDMGSLPDMPGPPPVKASKKAATSKA--- 1020
                      :..||..|     .:||:   |.:|..|:.|         .|.:::.:|.:.
 Worm   838 MEEHTIIHLGLGLNEAVPFVKRVDQKGR---PVSSLTDLNS---------EKMNERKSTKRKMLD 890

  Fly  1021 KAQAAAAAAAAASSQQQQQKGSAATPTPPPPVSTTPGCLQQDPFNAAMVSSNSSQSST---ASTS 1082
            |.:...........::...||            |..|..:|.|......||....|..   .|:|
 Worm   891 KVEKMEVGEDEEDDEESVDKG------------TDDGDYKQRPEKKRKQSSEEPASDPELFGSSS 943

  Fly  1083 QHSVSTSESQQNSIYNQSFNAEKQQPGQQQPQNTLHQQHPTPPPPQQQQQQQQQQQALPQSRVGP 1147
            |.:...||....:..|.|. ..|...|:           |||                     ..
 Worm   944 QPTRQLSERATRNRINYSL-LSKNGSGK-----------PTP---------------------ST 975

  Fly  1148 GELHLQRMNSFGQDGQFHFES-NPAAGAYQQHQLISQYQQQQQQQQQQ--------QQQQPQQQQ 1203
            ...:|:::  .|..|....|| .|.......|..|..:.:.:...::.        :..:|...:
 Worm   976 SSANLEKL--AGSSGGASSESPEPDESVEVSHWKIRTFLRSEYGVKESLKCPDCPYKSSEPDVLE 1038

  Fly  1204 QHHLAQQQQQHMRSHTPQSPHPPHPSQLQQQQPQ---QHF---SSPHHMPPMHHQHQLMMQQQHR 1262
            :|     :..||...||: |:...........|.   ||.   |...:..||..:|     .:||
 Worm  1039 KH-----RYYHMTKTTPR-PYACSDCTFNTYTPTALLQHLKLHSEGVYFDPMVKKH-----MKHR 1092

  Fly  1263 HNQRSPLHHHPAAQ---------QLQQQHQQPSHSPQHQHARLQ------SPQPAPVQQQQQQQQ 1312
            .....|    |..:         :.........||..|:...:.      ..||..::.|:.:.:
 Worm  1093 KGDSIP----PGVKGYYCKNCSFKTSIHRNFIEHSAYHRQQLINRINITLKRQPPRIEYQRPKLK 1153

  Fly  1313 QQ---------------QQQQQQFLQQQAADTWGNM----------NFGNPPNNQQVE---LKDN 1349
            .|               ...|..|::......|..:          |..:..:..|:.   :||.
 Worm  1154 HQFVAKNAKYCKKCTFKCVSQSNFIEHLDRHGWNQLYKCYSCDYSDNTKSVVDFHQLNHHIVKDQ 1218

  Fly  1350 KFY-IVESAEFLGLPMNVPPSPQQQQQQAVSKPQQQQQQQHPQPQQ 1394
            ..: |.:||:|            :.:...:..|:.|.::..|.|.:
 Worm  1219 TLHSICQSAKF------------RLENGVIQIPEFQTEKSKPTPDE 1252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368	7/20 (35%)
		C2H2 Zn finger	751..773	CDD:275368	7/86 (8%)
		C2H2 Zn finger	781..801	CDD:275368	8/24 (33%)
		PHA00733	<804..860	CDD:177301	19/91 (21%)
		C2H2 Zn finger	811..827	CDD:275368	8/20 (40%)
		C2H2 Zn finger	839..860	CDD:275368	4/20 (20%)
		C2H2 Zn finger	868..888	CDD:275368	6/45 (13%)
		C2H2 Zn finger	897..913	CDD:275368	4/26 (15%)
		C2H2 Zn finger	926..946	CDD:275368	6/19 (32%)
		KREPA	<944..>1009	CDD:483960	17/131 (13%)
		C2H2 Zn finger	954..975	CDD:275368	6/53 (11%)
spr-4	NP_001020993.1	C2H2 Zn finger	114..134	CDD:275368	6/19 (32%)
		C2H2 Zn finger	143..163	CDD:275368	4/25 (16%)