Protein Alignment Prosalpha3 and PRE6

DIOPT Version :10

• Sequence 1: NP_476691.1
• Gene: Prosalpha3 / 37378
• FlyBaseID: FBgn0261394
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_014604.1
• Gene: PRE6 / 854119
• SGDID: S000005398
• Length: 254
• Species: Saccharomyces cerevisiae
• Alignment Length: 268
• Identity: 86/268 - (32%)
• Similarity: 138/268 - (51%)
• Gaps: 37/268 - (13%)

  Fly     5 YDSRTTIFSPEGRLYQVEYAMEAISHAGTC-LGILAEDGILLAAECRSTNKLLDSAIPSEKIYRL 68
            ||...:||||:|.::|||||:||:.. ||| :|:..::.::|..|.|||.||.|:.|...|:.::
Yeast     4 YDRALSIFSPDGHIFQVEYALEAVKR-GTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKI 67

  Fly    69 NDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPFGVS 133
            :.::|.|.:|:.:|:.:|..:.|:.||.::.:..:.:..|.|..::..::|.|||.||.||||||
Yeast    68 DSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVS 132

  Fly   134 LLYMGWDNKYGY-QLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKEN-------VKLTL- 189
            .|..|:|.:... :|||::|||.|..|.|..||.|.......|::....||.       ||||:
Yeast   133 TLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVR 197

  Fly   190 -------ADAKDLAIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYTKVQ 247
                   ..||::.|.|:....|...|:.|::.....|                   ||:..:.|
Yeast   198 SLLEVVQTGAKNIEITVVKPDSDIVALSSEEINQYVTQ-------------------IEQEKQEQ 243

  Fly   248 AEAEAAKK 255
            .|.:..||
Yeast   244 QEQDKKKK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	79/230 (34%)
PRE6	NP_014604.1	proteasome_alpha_type_7	4..215	CDD:239724	75/211 (36%)