Protein Alignment Prosalpha3 and PSMB7

DIOPT Version :10

• Sequence 1: NP_476691.1
• Gene: Prosalpha3 / 37378
• FlyBaseID: FBgn0261394
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_002790.1
• Gene: PSMB7 / 5695
• HGNCID: 9544
• Length: 277
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 55/245 - (22%)
• Similarity: 105/245 - (42%)
• Gaps: 31/245 - (12%)

  Fly    23 YAMEAISHAGTCL-GILAEDGILLAAECRSTNKLLDSAIPSEKIYRLNDNMVCSVAGITSDANVL 86
            |.:..:...||.: |::.:|||:|.|:.|:|..::.:.....||:.::.|:.|..||..:|.::.
Human    34 YKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMT 98

  Fly    87 TSELRLIAQRYQFSYG---EVIPCEQLVSHLCDIKQAYTQYGGKRPFGVSLLYMGWDNKYGYQLY 148
            |..:....:.:..|.|   .|:...::      :||...:|.|.  .|.:|:..|.| ..|..||
Human    99 TQLISSNLELHSLSTGRLPRVVTANRM------LKQMLFRYQGY--IGAALVLGGVD-VTGPHLY 154

  Fly   149 QSDPSGNYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDLAIKVLS----------MT 203
            ...|.|:........:|:...||:::.:    ||....:...:||:|..:.::          ..
Human   155 SIYPHGSTDKLPYVTMGSGSLAAMAVFE----DKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSN 215

  Fly   204 LDTTKLTPEKVEMATLQRVDNKTVYSV----LEKPDVEKLIEKYTKVQAE 249
            :|...::..|::......|.||....:    .||.....|.||.|.::.|
Human   216 IDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIE 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	45/209 (22%)
PSMB7	NP_002790.1	proteasome_beta_type_7	44..232	CDD:239732	43/200 (22%)
		Pr_beta_C	235..271	CDD:463597	9/31 (29%)