DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha3 and PSMB1

DIOPT Version :9

Sequence 1:NP_476691.1 Gene:Prosalpha3 / 37378 FlyBaseID:FBgn0261394 Length:264 Species:Drosophila melanogaster
Sequence 2:NP_002784.1 Gene:PSMB1 / 5689 HGNCID:9537 Length:241 Species:Homo sapiens


Alignment Length:249 Identity:56/249 - (22%)
Similarity:95/249 - (38%) Gaps:43/249 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 SRTTIFSPEGRLYQVEYAMEA--------------ISHAGTCLGILAEDGILLAAECRSTNKLLD 57
            |.|.::|..||    :..||.              :.:.||.|.|..||..::|::.|.:.....
Human     3 SSTAMYSAPGR----DLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSI 63

  Fly    58 SAIPSEKIYRLNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYT 122
            ....|.|.|:|.|..|...:|...|...||..:....:.|:.|..:.:....:.:.|..|..:..
Human    64 HTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRR 128

  Fly   123 QYGGKRPFGVSLLYMGWDNKYGYQLYQSDPSGNY--GGWKATCIGNNFGAAISMLKQELADK--- 182
            .:    |:.|..:..|.|.:....:|..||.|:|  ..:||       |.:.|.:.|.|.|.   
Human   129 FF----PYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKA-------GGSASAMLQPLLDNQVG 182

  Fly   183 -------ENVKLTLADAKDLAIKVLSMTLDTTKLTPE--KVEMATLQRVDNKTV 227
                   |:|.|:|..|..|...|.....:....|.:  ::.:.|.:.:..:||
Human   183 FKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETV 236

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha3NP_476691.1 PTZ00246 1..245 CDD:173491 56/249 (22%)
proteasome_alpha_type_4 3..219 CDD:239721 53/239 (22%)
PSMB1NP_002784.1 proteasome_beta_type_1 30..241 CDD:239726 49/218 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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