Protein Alignment Prosalpha3 and PSMA7

DIOPT Version :10

• Sequence 1: NP_476691.1
• Gene: Prosalpha3 / 37378
• FlyBaseID: FBgn0261394
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_002783.1
• Gene: PSMA7 / 5688
• HGNCID: 9536
• Length: 248
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 84/257 - (32%)
• Similarity: 140/257 - (54%)
• Gaps: 14/257 - (5%)

  Fly     5 YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEKIYRLN 69
            ||...|:|||:|.|:|||||.||:....|.:|:...|.::|..|.:|..||.|.. ...||..|:
Human     3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDER-TVRKICALD 66

  Fly    70 DNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPFGVSL 134
            ||:..:.||:|:||.::.:..|:..|.::.:..:.:..|.:..::..:||.|||..|:||||:|.
Human    67 DNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISA 131

  Fly   135 LYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDLAIK- 198
            |.:|:|.....:|||:||||.|..|||..||....:....|::...|:      ..:..||.||
Human   132 LIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDE------AIETDDLTIKL 190

  Fly   199 VLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYTKVQAEAEAAKKEKQAK 260
            |:...|:..:...:.:|:|.::|..:   ..:|...::||.:   .:::.|.|..:|:||.|
Human   191 VIKALLEVVQSGGKNIELAVMRRDQS---LKILNPEEIEKYV---AEIEKEKEENEKKKQKK 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	74/214 (35%)
PSMA7	NP_002783.1	proteasome_alpha_type_7	3..211	CDD:239724	74/214 (35%)