DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Prosalpha3 and PSMA3

DIOPT Version :9

Sequence 1:NP_476691.1 Gene:Prosalpha3 / 37378 FlyBaseID:FBgn0261394 Length:264 Species:Drosophila melanogaster
Sequence 2:NP_002779.1 Gene:PSMA3 / 5684 HGNCID:9532 Length:255 Species:Homo sapiens


Alignment Length:256 Identity:75/256 - (29%)
Similarity:132/256 - (51%) Gaps:14/256 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEKIYRLN 69
            ||...:.|||:||::||||||:|:.::.|.:||..:||::...|....:||.:.. .:::::.::
Human     8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEG-SNKRLFNVD 71

  Fly    70 DNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPFGVSL 134
            .::..:|||:.:||..|....|..|..::.::|..||.:.|...:.....|||.|...||||.|.
Human    72 RHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSF 136

  Fly   135 LYMGWDNKYGYQLYQSDPSG-NYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDLAIK 198
            :...:....|.|||..|||| :||.|     |...|.|....|.|:...:..::|..|......|
Human   137 MLGSYSVNDGAQLYMIDPSGVSYGYW-----GCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAK 196

  Fly   199 VLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYTKVQAEAEAAKKEKQA 259
            ::.:..|..|....::|::.:..:.|.. :.::.| |:.:..|||.|     |:.|:|.::
Human   197 IIYIVHDEVKDKAFELELSWVGELTNGR-HEIVPK-DIREEAEKYAK-----ESLKEEDES 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha3NP_476691.1 PTZ00246 1..245 CDD:173491 71/240 (30%)
proteasome_alpha_type_4 3..219 CDD:239721 65/214 (30%)
PSMA3NP_002779.1 proteasome_alpha_type_3 5..217 CDD:239720 65/214 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1222564at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

Return to query results.
Submit another query.