Protein Alignment Prosalpha3 and PSMA3

DIOPT Version :10

• Sequence 1: NP_476691.1
• Gene: Prosalpha3 / 37378
• FlyBaseID: FBgn0261394
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_002779.1
• Gene: PSMA3 / 5684
• HGNCID: 9532
• Length: 255
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 75/256 - (29%)
• Similarity: 132/256 - (51%)
• Gaps: 14/256 - (5%)

  Fly     5 YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEKIYRLN 69
            ||...:.|||:||::||||||:|:.::.|.:||..:||::...|....:||.:.. .:::::.::
Human     8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEG-SNKRLFNVD 71

  Fly    70 DNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPFGVSL 134
            .::..:|||:.:||..|....|..|..::.::|..||.:.|...:.....|||.|...||||.|.
Human    72 RHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSF 136

  Fly   135 LYMGWDNKYGYQLYQSDPSG-NYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDLAIK 198
            :...:....|.|||..|||| :||.|     |...|.|....|.|:...:..::|..|......|
Human   137 MLGSYSVNDGAQLYMIDPSGVSYGYW-----GCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAK 196

  Fly   199 VLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYTKVQAEAEAAKKEKQA 259
            ::.:..|..|....::|::.:..:.|.. :.::.| |:.:..|||.|     |:.|:|.::
Human   197 IIYIVHDEVKDKAFELELSWVGELTNGR-HEIVPK-DIREEAEKYAK-----ESLKEEDES 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	65/214 (30%)
PSMA3	NP_002779.1	proteasome_alpha_type_3	5..217	CDD:239720	65/214 (30%)