DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3 and psma4

DIOPT Version :9

Sequence 1:	NP_476691.1	Gene:	Prosalpha3 / 37378	FlyBaseID:	FBgn0261394	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001007998.1	Gene:	psma4 / 493360	XenbaseID:	XB-GENE-5837209	Length:	261	Species:	Xenopus tropicalis

Alignment Length:	264	Identity:	182/264 - (68%)
Similarity:	216/264 - (81%)	Gaps:	3/264 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARRYDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEKI 65
            |:||||||||||||||||||||||||||.||||||||||.||:|||||.|:.:||||....||||
Frog     1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKI 65

  Fly    66 YRLNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPF 130
            |:|||:|.||||||||||||||:|||||||||...|.|.|||||||:.||||||||||:||||||
Frog    66 YKLNDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPF 130

  Fly   131 GVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDL 195
            ||||||:|||..||:||||||||||||||||||||||..||:|||||:..:.:   :||..|..|
Frog   131 GVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGD---MTLKSALAL 192

  Fly   196 AIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYTKVQAEAEAAKKEKQAK 260
            |:|||:.|:|.:||:.||||:|||.|.:.||...||::.:||:||:.:.:.:|:.|..||||:.|
Frog   193 AVKVLNKTMDVSKLSAEKVEIATLTRENGKTKIRVLKQKEVEELIKLHEEEEAKIEREKKEKEQK 257

  Fly   261 QPTK 264
            :..|
Frog   258 EKDK 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	PTZ00246	1..245	CDD:173491	174/243 (72%)
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	162/215 (75%)
psma4	NP_001007998.1	proteasome_alpha_type_4	3..216	CDD:239721	162/215 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I1702
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2083
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2149
OMA	1	1.010	-	-		QHG54118
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003645
OrthoInspector	1	1.000	-	-		oto103520
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2516
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080