DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3 and psmb10

DIOPT Version :9

Sequence 1:	NP_476691.1	Gene:	Prosalpha3 / 37378	FlyBaseID:	FBgn0261394	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001002543.2	Gene:	psmb10 / 436816	ZFINID:	ZDB-GENE-040718-278	Length:	276	Species:	Danio rerio

Alignment Length:	212	Identity:	55/212 - (25%)
Similarity:	97/212 - (45%)	Gaps:	21/212 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EGRLYQVEYAMEAISHAGTCL-GILAEDGILLAAECRSTNKLLDSAIPSEKIYRLNDNMVCSVAG 78
            |..|.:..|:.......||.: |::.:||::|.|:.|:|:.::.:.....||:.:..|:.|..||
Zfish    25 EANLSEKGYSAPNARKTGTTIAGLVFKDGVILGADTRATDDMVVADKNCMKIHYIAPNIYCCGAG 89

  Fly    79 ITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPFGVSLLYMGWDNKY 143
            :.:||.|.|..:....:.:..|.|.. |...:|:.  .:||...:|.|.  .|.||:..|.|..
Zfish    90 VAADAEVTTQMMSSNVELHSLSTGRP-PLVAMVTR--QLKQMLFRYQGH--IGSSLIVGGVDVN- 148

  Fly   144 GYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDLAIKVLS------- 201
            |.|||...|.|:|.......:|:...:|||:.:    |:....:.|.:||.|....::
Zfish   149 GAQLYSVYPHGSYDKLPFLTMGSGAASAISVFE----DRYKPNMELEEAKQLVRDAITAGIFCDL 209

  Fly   202 ---MTLDTTKLTPEKVE 215
               ..:|...:|.:||:
Zfish   210 GSGSNVDLCVITDKKVD 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	PTZ00246	1..245	CDD:173491	55/212 (26%)
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	55/212 (26%)
psmb10	NP_001002543.2	PRE1	40..224	CDD:223711	50/193 (26%)
		proteasome_beta_type_7	43..231	CDD:239732	51/194 (26%)
		Pr_beta_C	237..270	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900