Protein Alignment Prosalpha3 and Prosalpha4

DIOPT Version :10

• Sequence 1: NP_476691.1
• Gene: Prosalpha3 / 37378
• FlyBaseID: FBgn0261394
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 81/273 - (29%)
• Similarity: 139/273 - (50%)
• Gaps: 37/273 - (13%)

  Fly     1 MARRYDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEKI 65
            |:.|||...|||||:|.|.|||||.||:....|.:|:...:.::|..|.:|..:|.:.. ...||
  Fly     1 MSSRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDR-KVRKI 64

  Fly    66 YRLNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPF 130
            ..|::::|.:.||:|:||.::.:..::..|.::.:..:.:..|.:...:..:||.|||..|:|||
  Fly    65 CMLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPF 129

  Fly   131 GVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAI-------SMLKQELADKENVKLT 188
            |:|.|..|:|......|:|::|||.:..:||...|.:  |.:       |..::|:|::..
  Fly   130 GISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRS--AKVVREFFEKSYREEEVANEHG---- 188

  Fly   189 LADAKDLAIKVLSMTLDTTKLTPEKVEMA------TLQRVDNKTVYSVLEKPDVEKLIEKYTKVQ 247
               |..|||:.|   |:..:.....:|:|      .|:.:|...:      .|..|:|||
  Fly   189 ---AVKLAIRAL---LEVAQSGQNNLEVAIMENGKPLKMLDTDVI------TDYVKIIEK----- 236

  Fly   248 AEAEAAKKEKQAK 260
            .:.|..:|:||.|
  Fly   237 EKEEELEKKKQKK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	68/228 (30%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	67/220 (30%)