DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3 and Psmb10

DIOPT Version :9

Sequence 1:	NP_476691.1	Gene:	Prosalpha3 / 37378	FlyBaseID:	FBgn0261394	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_038668.2	Gene:	Psmb10 / 19171	MGIID:	1096380	Length:	273	Species:	Mus musculus

Alignment Length:	184	Identity:	54/184 - (29%)
Similarity:	94/184 - (51%)	Gaps:	26/184 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ISHA---GTCL-GILAEDGILLAAECRSTNKLLDSAIPS---EKIYRLNDNMVCSVAGITSDANV 85
            :.||   ||.: |::..||::|.|:.|:||   ||.:..   |||:.:...:.|..||:.:|..:
Mouse    32 VPHARKTGTTIAGLVFRDGVILGADTRATN---DSVVADKSCEKIHFIAPKIYCCGAGVAADTEM 93

  Fly    86 LTSELRLIAQR---YQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPFGVSLLYMGWDNKYGYQL 147
            .|   |:.|.:   :..|.|.. |....|:.:  ::|...:|.|.  .|.||:..|.|.. |.||
Mouse    94 TT---RMAASKMELHALSTGRE-PRVATVTRI--LRQTLFRYQGH--VGASLVVGGVDLN-GPQL 149

  Fly   148 YQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDLAIKVLS 201
            |:..|.|:|.....|.:|:..|||:::|:    |:....:||..|::|.::.::
Mouse   150 YEVHPHGSYSRLPFTALGSGQGAAVALLE----DRFQPNMTLEAAQELLVEAIT 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3	NP_476691.1	PTZ00246	1..245	CDD:173491	54/184 (29%)
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	54/184 (29%)
Psmb10	NP_038668.2	20S_bact_beta	39..238	CDD:163402	52/177 (29%)
		proteasome_beta_type_7	40..226	CDD:239732	51/176 (29%)
		Pr_beta_C	232..267	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900