DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3216 and Phlpp1

DIOPT Version :9

Sequence 1:	NP_726013.2	Gene:	CG3216 / 37376	FlyBaseID:	FBgn0034568	Length:	1161	Species:	Drosophila melanogaster
Sequence 2:	XP_038946976.1	Gene:	Phlpp1 / 59265	RGDID:	621308	Length:	1718	Species:	Rattus norvegicus

Alignment Length:	164	Identity:	41/164 - (25%)
Similarity:	55/164 - (33%)	Gaps:	53/164 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 SRESKSTQLSRYTEVGEMGSTMRVYNVGVLMASHLDSPFDL-------ERCGPAVDLALDEINKV 122
            |.::.:|:|.|..|.....||     ||.:.......|.||       .||.|.|:.|..:
  Rat   235 SDQTPATELGRDVEPPPSSST-----VGAVRGPARAPPADLPLPGGAWTRCAPRVNPAPSD---- 290

  Fly   123 FLKPHNITLLKKKGSYPS-------CSGARAPGLAADMYFQDDVIAFIGPACAFALEPVARLAAY 180
                          |.|.       ||.:|||..|:|..             :|:|.|.|...:.
  Rat   291 --------------SSPGELFAGGPCSPSRAPRPASDTE-------------SFSLSPSAESVSD 328

  Fly   181 WNKPIITGMGDQPPSSEGE---LTVTSGILGRIH 211
            ...|..:|.|....|.|.|   .||.:|..|..|
  Rat   329 RLDPYSSGGGSSSSSEELEADPATVLTGPSGPPH 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368	34/139 (24%)
		ANF_receptor	107..479	CDD:279440	29/115 (25%)
		PKc_like	616..885	CDD:304357
		TyrKc	627..877	CDD:197581
		HNOBA	<882..939	CDD:285003
		CYCc	918..1109	CDD:214485
		Guanylate_cyc	945..1131	CDD:278633
Phlpp1	XP_038946976.1	Ubiquitin_like_fold	176..>224	CDD:421700
		PHA03247	<237..443	CDD:223021	40/162 (25%)
		RA_PHLPP1	<424..491	CDD:340760
		PH_PHLPP-like	498..594	CDD:270131
		PLN00113	602..>1109	CDD:215061
		leucine-rich repeat	604..624	CDD:275380
		leucine-rich repeat	625..655	CDD:275380
		leucine-rich repeat	679..701	CDD:275380
		leucine-rich repeat	702..724	CDD:275380
		leucine-rich repeat	725..771	CDD:275380
		leucine-rich repeat	772..795	CDD:275380
		leucine-rich repeat	796..816	CDD:275380
		leucine-rich repeat	817..858	CDD:275380
		leucine-rich repeat	859..881	CDD:275380
		leucine-rich repeat	882..904	CDD:275380
		leucine-rich repeat	905..926	CDD:275380
		leucine-rich repeat	927..950	CDD:275380
		leucine-rich repeat	951..974	CDD:275380
		leucine-rich repeat	977..1000	CDD:275380
		leucine-rich repeat	1001..1024	CDD:275380
		leucine-rich repeat	1067..1112	CDD:275380
		PP2Cc	1151..1403	CDD:214625
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900