Protein Alignment CG3216 and adcy1b

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_001161822.1
• Gene: adcy1b / 569499
• ZFINID: ZDB-GENE-100805-1
• Length: 1114
• Species: Danio rerio
• Alignment Length: 1084
• Identity: 232/1084 - (21%)
• Similarity: 383/1084 - (35%)
• Gaps: 363/1084 - (33%)

  Fly   230 LTRMSYC----QCRLILVFASVI---------------RQFNWN-----------------HVAL 258
            ||.|:||    :..|.|:|..::               .|..|.                 .|.:
Zfish   147 LTFMAYCLLPVRTGLALLFGLLLPLAHTLITASTLPDNTQRLWRSLVANTLLFTGVNVSGLFVRI 211

  Fly   259 LVDRSELFSWTVGKN-LEYGLR-------QEGLLSFVKELNGNEEEVYENYLKDAS-MYARVVIL 314
            |.:|::..::...:| :|..||       ||.||..:...| ...|:.|::||... ::.::.|.
Zfish   212 LTERAQRKAFLQARNCIEERLRMEDENEKQERLLMSLLPRN-VAMEMKEDFLKPPERIFHKIYIQ 275

  Fly   315 SVRGVLVRKFMLAAHSLGMTN-------GEWVFLDVEIFQSEYWGDKGWEMKDEHDAKARKAYEA 372
            ....|.:    |.|..:|.|:       .|.|.|..|:|      .|..|:..|:..:
Zfish   276 RHDNVSI----LFADIVGSTSLASQCTAQELVKLLNELF------GKFDELATENHCR------- 323

  Fly   373 LLRVSLLQP--------TSPKFQDFADNVRENAL--YDYNYTFGEGEEV--NFFIGAFYDGVYLL 425
              |:.:|..        |.|| .|.|....|..|  .|...:..|..||  |..:| .:.|..|.
Zfish   324 --RIKILGDCYYCVSGLTQPK-TDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVG-LHTGRVLC 384

  Fly   426 G-MALNE-------------TLTEGGDIRDGVNITRRMWNRTFEGITGHVRIDDNGDRDADYSIL 476
            | :.|.:             .:.|.|.:...|:|||    .|.|.:.|...::....|:....:|
Zfish   385 GVLGLRKWQYDVWSNDVTLANMMEAGGLPGKVHITR----STLECLNGDYEVEPGNGRERHAFLL 445

  Fly   477 DLDPINGKFSVVAHYSGVHKVYSAVHGKKIHWPGGREEPPPDVPPCGFLGNSTDCVGNFSTIMYS 541
            ..| |...|.|            ..|.:|| :||   ....|:.|...:        .|.|:.|.
Zfish   446 KHD-IETFFIV------------PPHRRKI-FPG---LILSDIKPAKKM--------KFKTVCYL 485

  Fly   542 VFGLLLFLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEMGGMFGSKGGLQRLDVENISLQ 606
                     ||.|:.|  :|..:.....:|:            |....|.|..:.|...|.
Zfish   486 ---------LVQLMHC--RKMFRAEIPFSNV------------MNCEDGDKRRVLRSAPEK---- 523

  Fly   607 QFGIHSGRASIASFTSLPPQVYTTIGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARDVSHE--- 668
               :.:...:.||.....|.  |.:.::....:..::......||....|    ..||...|
Zfish   524 ---LRNRTPTAASAPQSSPG--TRVNRYINRLIEARQTESDTADLNYLTL----MYRDSERERRY 579

  Fly   669 ---NTVRFVGACI---------------DLPRPT-VLILTEYCSRGSLKDVLENEAIELDWNFRM 714
               |...|.||.:               .:|:.| ||:|..:|
Zfish   580 HQLNDEYFTGAVVLSLLLVVLLGFLYLLIIPQGTVVLVLLVFC---------------------- 622

  Fly   715 SLIHDIVKGMNYLHNSDVAAHG-----KLRSCNCLIDGRFVLKISD---FGLRTLTTPSDFVR-- 769
              |..:|..:.|||.:.|....     ::|:..|:.....:..::.   .|......||:..|
Zfish   623 --ICFLVVCIMYLHITRVQCFPGCLTIQIRTALCVFIVLLIYAVAQACVVGCMPWLWPSNSTRSI 685

  Fly   770 ---------------------------------DQNYYLKLLWIAPELLPLTTIPGCCPATQRGD 801
                                             ....:|::.||...:|.|
Zfish   686 VIIDAAAGLNRTMAELPCAGAQYAFLCCMLGTLSMALFLRVSWIPKTILLL-------------- 736

  Fly   802 VYSFGIILEEIVNRGGPYQEARQQMDVHTILHKVRQCNGFR-----PLIRERECPPDLLELMEKC 861
                 ::|...:                |||    :.:|||     .|:..|...| ||.|:
Zfish   737 -----LLLVLYI----------------TIL----ELSGFRRASGWALLSVRGLEP-LLSLL--- 772

  Fly   862 WADNQEERPTFST-IRSNIRTIMKGFCENLMDDLLNRME-QYANNLESLVEEK--TRQLSLEKQR 922
                     .||| :..:.|.:          ||..|:: .:|...|   ||:  ..::.|:.:|
Zfish   773 ---------LFSTAVALHSRQL----------DLKLRLDFLWATQAE---EERDGMEKVKLDNKR 815

  Fly   923 TEELLYQILPRPVAQQLMAGDLVEP-------EEFSSVTIYFSDIVGFT----ELCARSSPMDVV 976
               :|:.:||..|||..:   |..|       :.::.|.:.|:.|..|.    ||...:..::.:
Zfish   816 ---ILFNLLPVHVAQHFL---LSNPRNMDLYYQSYAQVGVLFASIPNFNDFYIELDGNNMGVECL 874

  Fly   977 NFLNDLYSTFDRIIG---FYDVYKVETIGDAYLVVSGLPEPNGDK-------HAREIALMALDIL 1031
            ..||::.:.||.::.   :.|:.|::|||..|:...||....|.|       |...||..|:::.
Zfish   875 RLLNEIIADFDELMDKECYKDIEKIKTIGSTYMSAVGLVPTIGTKAKKSTATHLSTIADFAIEMF 939

  Fly  1032 RAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSS 1096
            ..:...|.:...::  .:|:|::.|.|.|||:|.:.|.|.::|:|||.||||:|||.||||.|:.
Zfish   940 DVLDEINYQSYNDF--VLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPGKIQVTE 1002

  Fly  1097 ATKAILDKFGTFQMEQRGDVELKGKGTVTTYWLNSTSEGEARPP 1140
            ....:|.  ..:.:..||:|.:||||.:.||:|    ||:|:.|
Zfish  1003 DVYRLLQ--NNYDLMCRGNVSVKGKGQMLTYFL----EGKAQDP 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368	74/343 (22%)
		ANF_receptor	107..479	CDD:279440	70/326 (21%)
		PKc_like	616..885	CDD:304357	54/339 (16%)
		TyrKc	627..877	CDD:197581	50/320 (16%)
		HNOBA	<882..939	CDD:285003	15/59 (25%)
		CYCc	918..1109	CDD:214485	62/211 (29%)
		Guanylate_cyc	945..1131	CDD:278633	63/206 (31%)
adcy1b	NP_001161822.1	AC_N	<128..270	CDD:292831	26/123 (21%)
		CYCc	236..431	CDD:214485	51/220 (23%)
		Guanylate_cyc	272..454	CDD:278633	46/207 (22%)
		DUF1053	498..585	CDD:283888	17/111 (15%)
		CYCc	806..1012	CDD:214485	62/215 (29%)
		Guanylate_cyc	839..1035	CDD:278633	62/203 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900