DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3216 and ADCY10

DIOPT Version :9

Sequence 1:NP_726013.2 Gene:CG3216 / 37376 FlyBaseID:FBgn0034568 Length:1161 Species:Drosophila melanogaster
Sequence 2:NP_060887.2 Gene:ADCY10 / 55811 HGNCID:21285 Length:1610 Species:Homo sapiens


Alignment Length:303 Identity:69/303 - (22%)
Similarity:110/303 - (36%) Gaps:98/303 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   915 QLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFL 979
            ::||:|...|.:|.||..:.:...|        .|...|||.|.::: |.:   :....::...:
Human   262 EMSLQKYVMESILKQIDNKQLQGYL--------SELRPVTIVFVNLM-FED---QDKAEEIGPAI 314

  Fly   980 NDLYSTFDRIIGFY--DVYKVETI--GDAYLVVSGLPEPNGDK------HAREIALMALDILRAV 1034
            .|.|.....::..:  .:.||...  |.::|.|.|.|   |:|      ||.|.|:...|....|
Human   315 QDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFP---GEKVPDELTHALECAMDIFDFCSQV 376

  Fly  1035 SSFNLRHKPEYKIQ-IRIGMHSGSVCAGVVGKKMPH-YCLFGDTVNTASRMESTGQPGKIHVSSA 1097
                      :||| :.||:.||.|..|:||..:.| |.:.|..||.|:|| ....||.:...|.
Human   377 ----------HKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARM-MMYYPGIVTCDSV 430

  Fly  1098 T-------------------KAILDKFGTFQ----------------MEQRGDVELKGKGTVTTY 1127
            |                   |.:.|....:|                ..::.|..|.|:.....|
Human   431 TYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEKVMFGMACLICNRKEDYPLLGRNKEINY 495

  Fly  1128 WL---------NSTSEGEARPPTPQILTTDEVPFPLLFAGMGK 1161
            ::         ||:          |:|..:.:|      |.||
Human   496 FMYTMKKFLISNSS----------QVLMYEGLP------GYGK 522

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3216NP_726013.2 PBP1_NPR_like 90..496 CDD:107368
ANF_receptor 107..479 CDD:279440
PKc_like 616..885 CDD:304357
TyrKc 627..877 CDD:197581
HNOBA <882..939 CDD:285003 7/23 (30%)
CYCc 918..1109 CDD:214485 55/221 (25%)
Guanylate_cyc 945..1131 CDD:278633 53/241 (22%)
ADCY10NP_060887.2 CHD 40..214 CDD:143636
AcyC <42..197 CDD:225025
CHD 292..461 CDD:143636 47/186 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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