DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3216 and adcy1a

DIOPT Version :9

Sequence 1:	NP_726013.2	Gene:	CG3216 / 37376	FlyBaseID:	FBgn0034568	Length:	1161	Species:	Drosophila melanogaster
Sequence 2:	NP_001161821.1	Gene:	adcy1a / 557026	ZFINID:	ZDB-GENE-070705-302	Length:	1114	Species:	Danio rerio

Alignment Length:	207	Identity:	70/207 - (33%)
Similarity:	116/207 - (56%)	Gaps:	16/207 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   915 QLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEE----------FSSVTIYFSDIVGFTELCAR 969
            ||..|.::.|.||..:|||.||.: |..|.::|.|          ..:|:|.|:||||||.|.::
Zfish   248 QLEDENEKQERLLMSLLPRNVAME-MKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ 311

  Fly   970 SSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRAV 1034
            .:..::|..||:|:..||.:.......:::.:||.|..||||.:|..| ||.....|.||::..:
Zfish   312 CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKAD-HAHCCVEMGLDMIDTI 375

  Fly  1035 SSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATK 1099
            :|  :....|..:.:|:|:|:|.|..||:|.:...|.::.:.|..|:.||:.|.|||:|::.||.
Zfish   376 TS--VAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPGKVHITKATL 438

  Fly  1100 AILDKFGTFQME 1111
            ..|:  |.:::|
Zfish   439 ECLN--GDYEVE 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357
		TyrKc	627..877	CDD:197581
		HNOBA	<882..939	CDD:285003	11/23 (48%)
		CYCc	918..1109	CDD:214485	67/200 (34%)
		Guanylate_cyc	945..1131	CDD:278633	57/177 (32%)
adcy1a	NP_001161821.1	AC_N	<154..285	CDD:292831	15/37 (41%)
		CYCc	251..446	CDD:214485	67/200 (34%)
		Guanylate_cyc	287..469	CDD:278633	55/167 (33%)
		DUF1053	513..601	CDD:283888
		CYCc	819..1029	CDD:214485
		Guanylate_cyc	852..1048	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900