Protein Alignment CG3216 and npr1b

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: XP_009290669.2
• Gene: npr1b / 555911
• ZFINID: ZDB-GENE-100805-4
• Length: 1070
• Species: Danio rerio
• Alignment Length: 1094
• Identity: 447/1094 - (40%)
• Similarity: 643/1094 - (58%)
• Gaps: 93/1094 - (8%)

  Fly    73 LSRYTEVGE-MGSTMRVYN------VGVLMASHLDS-PFDLERCGPAVDLALDEI--NKVFLKPH 127
            ||.:|::.: .||....:|      :.|::..|..| |:...|.|||:|.|:..:  |...|..|
Zfish    25 LSTWTKISKHQGSHKGAHNHSNDIVLAVILPQHNTSYPWAWPRVGPALDRAIARVNANPNLLPRH 89

  Fly   128 NI--TLLKKKGSYPSCSGARAPGLAADMYFQDDVIAFIGPACAFALEPVARLAAYWNKPIITGMG 190
            .:  .....:.....||.:.||.:|.|:.|:.:..|||||.|.:...||....|:|..|:||  .
Zfish    90 RVRHVFANSEDRDGICSESMAPLMAVDLKFEHNPWAFIGPGCDYTSSPVGLFTAHWGLPMIT--A 152

  Fly   191 DQPPSSEGELTVTSGILGRIHKWKNENTGMFKDKSKYPTLTRMSYCQCRLILVFASVIRQFNWNH 255
            ..|..:..::.:.:.|         .|||        ||..::......|       .|.|.||.
Zfish   153 GAPAVAFLQMEIYTSI---------TNTG--------PTHKKLGEYALHL-------YRHFGWNQ 193

  Fly   256 VALLVDRSELFSWT-VGKNLEYGLRQEGLLSFVKELN---------GNEEEV-YENYLKDASMYA 309
            .:||     :||.| :|:...| ...|||.:.:.|.|         .|:..| |...|.......
Zfish   194 HSLL-----MFSDTKMGERACY-FALEGLYTEMHEENITTMDLVFEENKGPVNYSELLHKIQGDG 252

  Fly   310 RVVILSVRGVLVRKFMLAAHSLGMTNGEWVFLDVEIFQSEYWG--DKGWEMKDEHDAKARKAYEA 372
            |||.:.....:.|:.::..|..|:...|:||..::||...:..  .:.|...|..|..|::|:::
Zfish   253 RVVFVCCSPDVFRQLIVHFHKAGLPKEEYVFFYIDIFGHSFRSRPSQPWARGDSDDVFAKEAFQS 317

  Fly   373 LLRVSLLQPTSPKFQDFADNVRENALYDYNYTFGEGEEVNFFIGAFYDGVYLLGMALNETLTEGG 437
            :..::.|:|.:.:::||..:::.:|...:|:|. :...:|...|.||||:.|...||||:|::..
Zfish   318 VKILTYLEPQNQEYKDFVTDLKSDAKRMFNFTV-DDSLMNIISGGFYDGLMLYCHALNESLSDSH 381

  Fly   438 DIRDGVNITRRMWNRTFEGITGHVRIDDNGDRDADYSILDLDPIN-GKFSVVAHYSGVHKVYSAV 501
            :...|.::::||||||:.|:||.|:||:||||:.|:::.|:..|| |.|.:||.|:|..|..:.:
Zfish   382 ERPSGESVSKRMWNRTYYGVTGLVQIDENGDRETDFALWDMADINTGDFQIVAVYNGTQKEMNIL 446

  Fly   502 HGKKIHWPGGREEPPPDVPPCGFLGNSTDCVGNFSTIMYSVFGLLLFLGL--VFLVICLLQKQMK 564
            .|..|.||||:  .|.|||.|||...:..|... :..|:.:..::|||.|  :|.|...:.:::|
Zfish   447 PGMAIQWPGGK--VPMDVPTCGFKNENPACRAR-TIAMHQMISIVLFLILIIIFTVTVFIYRKLK 508

  Fly   565 LSKELNNMSWRVRPDDVLIEMGGM------FGSKGGLQRLDVENISLQQFGIHSGRASIASFTSL 623
            |.|||....||:..||  |:|..:      .|||        ..:||:.....|...:..:|
Zfish   509 LEKELVAQLWRISWDD--IQMSHLEKALRSTGSK--------LTLSLRGSNYGSLLTTDGNF--- 560

  Fly   624 PPQVYTTIGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLIL 688
              ||:...|.|||..||||.:|.::|:||.::|:|:|..|||.:|:..||:|||||  .|.:.|:
Zfish   561 --QVFAKTGYFKGNIVAIKYINRRRVELTRKVLFELKHMRDVQNEHLTRFIGACID--PPNICIV 621

  Fly   689 TEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKI 753
            ||||.||||:::|||::|.|||.|:.|||.||||||.:||||.:.:||.|:|.||::|.||||||
Zfish   622 TEYCPRGSLQNILENDSITLDWMFKYSLISDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKI 686

  Fly   754 SDFGLRTLTTPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCP-ATQRGDVYSFGIILEEIVNRGG 817
            :|:||.::.|.||.....:||.:.||:||||..:...|   | .||:||||||||||:|:..|.|
Zfish   687 TDYGLSSIRTESDTEDAHSYYARKLWLAPELSRMECFP---PGGTQKGDVYSFGIILQEVALRRG 748

  Fly   818 PYQEARQQMDVHTILHKVR--QCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIR 880
            .:......:....|:.:|.  :....||.:..:....:|.:||::|||:...:||.||.|...:|
Zfish   749 VFYLEGDLLSPKEIVDRVALGEWPYLRPSLNPQAHSEELGQLMQRCWAEEPSDRPEFSHISVLLR 813

  Fly   881 TIMKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLV 945
            ...:....|::|:||:||||||||||.||||:|:....||::.|.|||||||..||:||..|:.|
Zfish   814 KQNREHRSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETV 878

  Fly   946 EPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSG 1010
            :.|.|.|||||||||||||.|.|.|:|:.||..|||||:.||.||..:||||||||||||:||||
Zfish   879 QAEAFDSVTIYFSDIVGFTSLSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSG 943

  Fly  1011 LPEPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGD 1075
            ||..||..|.||||.|:|.:|.||.:|.:||:|:.::::|||:|||.|||||||.|||.||||||
Zfish   944 LPVRNGKLHGREIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGD 1008

  Fly  1076 TVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWL 1129
            ||||:|||||.|:|.||||||||:|:|.:|..||:|.|||||:||||.:.||||
Zfish  1009 TVNTSSRMESNGEPLKIHVSSATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWL 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575	125/435 (29%)
		Protein Kinases, catalytic domain	616..885	CDD:473864	120/271 (44%)
		HNOBA	<891..939	CDD:462234	30/47 (64%)
		CYCc	918..1109	CDD:214485	124/190 (65%)
npr1b	XP_009290669.2	Periplasmic_Binding_Protein_type1	50..453	CDD:471960	126/435 (29%)
		PK_GC-A_B	544..818	CDD:270944	123/283 (43%)
		HNOBA	<818..872	CDD:462234	31/53 (58%)
		CYCc	851..1036	CDD:214485	122/184 (66%)