Protein Alignment CG3216 and Gucy1b1

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_059497.1
• Gene: Gucy1b1 / 54195
• MGIID: 1860604
• Length: 620
• Species: Mus musculus
• Alignment Length: 556
• Identity: 151/556 - (27%)
• Similarity: 234/556 - (42%)
• Gaps: 128/556 - (23%)

  Fly   658 EIKQARDVSHENTVRFVGA-------CIDLPRPTVLILTEYCSRGSLKDVLENEAIELDWNFRMS 715
            |..|..|..|::.......       |.|..:...|||..|..|..|:|::            :.
Mouse    96 EFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIV------------IG 148

  Fly   716 LIHDIVKGMNYLHNSDV---AAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQNYYLKL 777
            :|..:.:   .:|.:::   ....:...|:   ..:|:::..:      :...||..|.:.:.:.
Mouse   149 IIKTVAQ---QIHGTEIDMKVIQQRNEECD---HTQFLIEEKE------SKEEDFYEDLDRFEEN 201

  Fly   778 LWIAPELLPLTTIPGCCPATQRGDVYSFGIILEE--IVNRGG-------------------PYQE 821
            ......:.|.|    .|.|      :.|.||.:.  :|.:.|                   .:..
Mouse   202 GTQESRISPYT----FCKA------FPFHIIFDRNLVVTQCGNAIYRVLPQLQPGNCSLLSVFSL 256

  Fly   822 ARQQMDV--HTILHKVRQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIRTIMK 884
            .|..:|:  |.||..:....    ::|.:|   .||: :||...:::......|.:|...:.|..
Mouse   257 VRPHIDISFHGILSHINTVF----VLRSKE---GLLD-VEKLECEDELTGAEISCLRLKGQMIYL 313

  Fly   885 GFCENL----------MDDLLNR-----------------------MEQY--ANNLESLVEE--- 911
            ...:::          :|||..|                       .|:|  ...||.|.:.
Mouse   314 PEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQL 378

  Fly   912 KTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCAR----SSP 972
            ..|.|..||::|:.|||.:||..||.:|.....|..:.:.:|||.||.||||...|::    ...
Mouse   379 TLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGA 443

  Fly   973 MDVVNFLNDLYSTFDRIIGFYD---VYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRAV 1034
            |.:||.|||||:.||.:.....   ||||||:||.|:.||||||| ...|||.|..:|||::...
Mouse   444 MKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEP-CIHHARSICHLALDMMEIA 507

  Fly  1035 SSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATK 1099
            ....:..:   .:||.||:|:|.|..||:|::||.|||||:|||..||.|:||:.|||:||..|.
Mouse   508 GQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTY 569

  Fly  1100 AIL----DKFGTFQMEQRGDVELKGKGTVTTYWLNS 1131
            ..|    :....|.:|.||.|.:|||......|..|
Mouse   570 RCLMSPENSDPLFHLEHRGPVSMKGKKEPMQVWFLS 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357	43/259 (17%)
		TyrKc	627..877	CDD:197581	41/251 (16%)
		HNOBA	<882..939	CDD:285003	22/94 (23%)
		CYCc	918..1109	CDD:214485	87/201 (43%)
		Guanylate_cyc	945..1131	CDD:278633	85/196 (43%)
Gucy1b1	NP_059497.1	HNOB	2..166	CDD:311572	15/84 (18%)
		HNOBA	207..406	CDD:311573	44/216 (20%)
		Guanylate_cyc	412..605	CDD:306677	85/196 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810