Protein Alignment CG3216 and Gucy1a1

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_058786.2
• Gene: Gucy1a1 / 497757
• RGDID: 68436
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 160/616 - (25%)
• Similarity: 249/616 - (40%)
• Gaps: 188/616 - (30%)

  Fly   633 QFKGERVAIKKVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRG-- 695
            :|:...:|:::...|.         :||:.|:.|.:.         ||.|   :|..|..:.|
  Rat    84 EFERLNLALQRTLAKH---------KIKENRNSSEKE---------DLER---IIAEEAIAAGVP 127

  Fly   696 --SLKDVLENEAIELDWNFRMSL-------IHDIVKGMNYL-----HNSDVAAHGKLRSCNCL-I 745
              :|||.|..|..::.:.....:       :.|.:...:.|     |..:....|:|...:.| :
  Rat   128 VEALKDSLGEELFKICYEEDEHILGVVGGTLKDFLNSFSTLLKQSSHCQEAERRGRLEDASILCL 192

  Fly   746 DGRFVLKISDFGLRTLTTPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCPATQRGDVYSFGIILE 810
            |                      :||: :|.:.:..|:......:||...|..|       |:.|
  Rat   193 D----------------------KDQD-FLNVYYFFPKRTTALLLPGIIKAAAR-------ILYE 227

  Fly   811 -----------------EIVNRGGPY--------------QEARQQMDV-------------HTI 831
                             |.||:  ||              ...:.|..:             |.:
  Rat   228 SHVEVSLMPPCFRSECTEFVNQ--PYLLYSVHVKSTKPSLSPGKPQSSLVIPTSLFCKTFPFHFM 290

  Fly   832 LHK----VRQCNGFRPLIREREC--PPDLLELME-------------------------KCWADN 865
            |.:    ::..||.|.|:.:|:.  .|:..|..|                         :.| ||
  Rat   291 LDRDLAILQLGNGIRRLVNKRDFQGKPNFEEFFEILTPKINQTFSGIMTMLNMQFVIRVRRW-DN 354

  Fly   866 QEERPT---------FSTIRSNIRTIMKGFCENLMDDLLNR------------------------ 897
            ..::.:         ...:.|:....:...|.:.::|...|
  Rat   355 LVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQAR 419

  Fly   898 ----MEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFS 958
                :::....|::.:|...:.|..||::|.:||..|.|..|||||..|.:|:.::|:.||:.||
  Rat   420 AQDGLKKRLGKLKATLEHAHQALEEEKKKTVDLLCSIFPSEVAQQLWQGQIVQAKKFNEVTMLFS 484

  Fly   959 DIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREI 1023
            ||||||.:|::.||:.|:..||.||:.||:..|..||||||||||||.|..|| ....|.||.:|
  Rat   485 DIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGL-HRESDTHAVQI 548

  Fly  1024 ALMALDILRAVSSFNLRH-KPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTG 1087
            |||||.::...:.....| :|   |::|||:|||||.|||||.|||.|||||:.|..|::.||..
  Rat   549 ALMALKMMELSNEVMSPHGEP---IKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCS 610

  Fly  1088 QPGKIHVSSATKAILDKFGTFQMEQRGDVEL 1118
            .|.||:||..|..:|.....|....|...||
  Rat   611 VPRKINVSPTTYRLLKDCPGFVFTPRSREEL 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357	55/352 (16%)
		TyrKc	627..877	CDD:197581	54/344 (16%)
		HNOBA	<882..939	CDD:285003	16/84 (19%)
		CYCc	918..1109	CDD:214485	95/191 (50%)
		Guanylate_cyc	945..1131	CDD:278633	86/175 (49%)
Gucy1a1	NP_058786.2	HNOB	<111..234	CDD:285002	28/164 (17%)
		HNOBA	276..465	CDD:285003	30/189 (16%)
		CYCc	444..633	CDD:214485	96/192 (50%)
		Guanylate_cyc	471..642	CDD:278633	86/175 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810