DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3216 and CG32301

DIOPT Version :9

Sequence 1:	NP_726013.2	Gene:	CG3216 / 37376	FlyBaseID:	FBgn0034568	Length:	1161	Species:	Drosophila melanogaster
Sequence 2:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	87/346 - (25%)
Similarity:	153/346 - (44%)	Gaps:	78/346 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   840 GFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYANN 904
            |:..||       |.:..::|.|     |...:....         |..|::...|:|.::|  |
  Fly   177 GYMALI-------DKISTLDKVW-----ELTAYGAYL---------FFLNMLCMFLSRFQEY--N 218

  Fly   905 LES--------LVEEKTRQLSLEKQRTEELLYQILPRPVAQQL---MAGDLVEP----------- 947
            :.|        :.:....|:::::::.  ||..|:|..:|:.|   :|..:.|.
  Fly   219 MRSGILSRYQVVYQNLVFQMAMKEEKA--LLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTR 281

  Fly   948 ----EEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVV 1008
                |....|:|..:|:|.||.|.......|:|..|::|:.:||.........:::.:||:|..|
  Fly   282 HLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCV 346

  Fly  1009 SGLPE--PNGDKHAREIALMALDIL---RAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMP 1068
            :|:|.  |.   ||......|||::   |.||  ..|:|   ||.:|||:|||.:.||::|....
  Fly   347 TGIPSYFPT---HANACVNQALDMIEISREVS--KRRNK---KIDLRIGVHSGEILAGIIGLTKW 403

  Fly  1069 HYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDV----ELKGKGTVTTYWL 1129
            .:.::...|:..:|:||:|.||.:|:||.|..:||..  :..|:..|.    .|..:..::||.:
  Fly   404 QFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLDNH--YVYEEGTDTAKLDPLLQRSNLSTYLI 466

  Fly  1130 NSTSEGEARPPTPQILTTDEV 1150
            .|.        .|....||::
  Fly   467 RSR--------LPNFEDTDDL 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357	7/44 (16%)
		TyrKc	627..877	CDD:197581	7/36 (19%)
		HNOBA	<882..939	CDD:285003	13/64 (20%)
		CYCc	918..1109	CDD:214485	63/213 (30%)
		Guanylate_cyc	945..1131	CDD:278633	61/209 (29%)
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	54/163 (33%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900