DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3216 and Adcy10

DIOPT Version :9

Sequence 1:	NP_726013.2	Gene:	CG3216 / 37376	FlyBaseID:	FBgn0034568	Length:	1161	Species:	Drosophila melanogaster
Sequence 2:	NP_766617.2	Gene:	Adcy10 / 271639	MGIID:	2660854	Length:	1614	Species:	Mus musculus

Alignment Length:	230	Identity:	61/230 - (26%)
Similarity:	94/230 - (40%)	Gaps:	49/230 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   887 CENLMD-----DLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVE 946
            |...||     |..|.: :.|..|||   :...:|||:|...|.:|.||..:.:...|
Mouse   233 CMGFMDYYPSGDHKNFL-RLACMLES---DPELELSLQKYVMEIILKQIDDKQLRGYL------- 286

  Fly   947 PEEFSSVTIYFSDIVGFTE--------LCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGD 1003
             .|...|||.|.::: |.|        ...:::.:.:.:.|.......:::..|       ..|.
Mouse   287 -SELRPVTIVFVNLM-FKEQDKVEVIGSAIQAACVHITSVLKVFRGQINKVFMF-------DKGC 342

  Fly  1004 AYLVVSGLP---EPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQ-IRIGMHSGSVCAGVVG 1064
            ::|.|.|.|   .|:...||.|.|:...|....|          :||: :.||:.||.|..|:||
Mouse   343 SFLCVFGFPGEKAPDEITHALESAVDIFDFCSQV----------HKIRTVSIGVASGIVFCGIVG 397

  Fly  1065 KKMPH-YCLFGDTVNTASRMESTGQPGKIHVSSAT 1098
            ..:.| |.:.|..||.|:|| ....||.:...|.|
Mouse   398 HTVRHEYTVIGQKVNIAARM-MMYYPGIVSCDSVT 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357
		TyrKc	627..877	CDD:197581
		HNOBA	<882..939	CDD:285003	17/56 (30%)
		CYCc	918..1109	CDD:214485	50/194 (26%)
		Guanylate_cyc	945..1131	CDD:278633	43/167 (26%)
Adcy10	NP_766617.2	CHD	40..214	CDD:143636
		CHD	292..461	CDD:143636	42/159 (26%)
		COG3899	485..>959	CDD:226415
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900