Protein Alignment CG3216 and Gucy2f

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_001007577.1
• Gene: Gucy2f / 245650
• MGIID: 105119
• Length: 1108
• Species: Mus musculus
• Alignment Length: 1107
• Identity: 367/1107 - (33%)
• Similarity: 574/1107 - (51%)
• Gaps: 139/1107 - (12%)

  Fly    89 YNVGVLMASHLDSPFDLERCGPAVDLALDEI-----------NKVFLKPHNI--TLLKKKGSYPS 140
            |.:||:      .|:   .|.|....||.|:           :|.|.:.::.  .:|.:     .
Mouse    53 YKIGVI------GPW---TCDPFFSKALPEVAAALAIERISRDKTFDRSYSFEYVILNE-----D 103

  Fly   141 CSGARAPGLAADMYFQDDVIAFIGPACAFALEPVARLAAYWNKPIITGMGDQPPSSEGELTVTSG 205
            |..::|  ||:.:..|.....|:|||.....|..:.|...|:|.|.:
Mouse   104 CQTSKA--LASFISHQQMASGFVGPANPGFCEAASLLGTSWDKGIFS------------------ 148

  Fly   206 ILGRIHKWKNENTGMFKDKSKYPTLTRMSYCQCRLILVFASVIRQFNWNHVALLVDRSELFSWTV 270
                   |...|..: .:|..:||.:|......|   |..:|::.|.|.|..::....:::..|.
Mouse   149 -------WACVNHEL-DNKHSFPTFSRTLPSPIR---VLVTVMKYFQWAHAGVISSDEDIWMHTA 202

  Fly   271 GKNLEYGLRQEGLLSFVKELNGNEEEVYENYLKDASM--YARVVILSVRGVLV-----RKFMLAA 328
            .: :...||.:||...|...:|.:.:..:..|:....  ..|::|:.:...|:     ..|:..|
Mouse   203 NR-VSSALRSQGLPVGVVLTSGRDSQSIQKALQQIRQADRIRIIIMCMHSALIGGETQTHFLELA 266

  Fly   329 HSLGMTNGEWVFL--DVEIFQSEYWGDKGWEMKDEHDAKARKAYEALLRVSLLQPTSPKFQDFAD 391
            |.|.||:|.:||:  ||.::...|.......::  ::.|.|:||:|:|.:::.......::.:|:
Mouse   267 HDLKMTDGTYVFVPYDVLLYSLPYKHSPYQVLR--NNPKLREAYDAVLTITVESHEKTFYEAYAE 329

  Fly   392 NVRENALYDYNYTFGEGEEVNFFIGAFYDGVYLLGMALNETLTEGGDIRDGVNITRRMWNRTFEG 456
            ......:.:.    .:..:|:...|..|:.:|.:..|:|..:.:.|. ....::.:...|..|.|
Mouse   330 AAARGEIPEK----PDSNQVSPLFGTIYNSIYFIAQAMNNAMKKNGR-ASAASLVQHSRNMQFYG 389

  Fly   457 ITGHVRIDDNGDRDADYSILDLD----PINGKFSVVAHYSGVHKVYSAVHGKKIHWPGGREEPPP 517
            ....::.|.||:..::|.|||.:    .:.|.::|     .:........|..||:||||  |..
Mouse   390 FNQLIKTDSNGNGISEYVILDTNGKEWELRGTYTV-----DMETELLRFRGTPIHFPGGR--PTS 447

  Fly   518 DVPPCGFLGNSTDCVGNF--STIMYSVFGLLLFL----GLVFLVICLLQKQMKLSKELNNMSWRV 576
            ....|.|..... |.|..  :..|...|.||:.|    |..:.:          .:.:|.:....
Mouse   448 ADAKCWFAERKI-CQGGIDPALAMMVCFALLIALLSINGFAYFI----------RRRINKIQLIK 501

  Fly   577 RPDDVLIEMGGM------FGSKGGLQRLDVENISLQQFG-IHSGRASIASFT--SLPPQVY--TT 630
            .|:.:|:.:..:      ||||.|.:    .::|.|... :.|||:...||:  ||.|..|  :.
Mouse   502 GPNRILLTLEDVTFINPHFGSKRGSR----ASVSFQIISEVQSGRSPRLSFSSGSLTPATYENSN 562

  Fly   631 IGQFKGERVAIKKV------NVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILT 689
            |..::|:.|.:||.      ::|.:..:...::|:  .:|:.|||....:|...|  .....|::
Mouse   563 IAIYEGDWVWLKKFPPGDFGDIKSIKSSASDVFEM--MKDLRHENVNPLLGFFYD--SGMFAIVS 623

  Fly   690 EYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKIS 754
            |:|||.||:|:|.|:.::|||.|:.||:.|::|||.|||:.:. .||:|:|.||::|||||||::
Mouse   624 EFCSRRSLEDILTNDDVKLDWMFKSSLLLDLIKGMKYLHHREF-IHGRLKSRNCVVDGRFVLKVT 687

  Fly   755 DFGLRTLTTPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCP-ATQRGDVYSFGIILEEIVNRGGP 818
            |:|...:........::....:|||.|||||   ..||... .:..||||||.||::|::.||.|
Mouse   688 DYGFNDILEMLRLSEEEPSEEELLWTAPELL---RAPGGIRLGSFAGDVYSFAIIMQEVMVRGAP 749

  Fly   819 YQEARQQMDVHTILHKVRQCNG-FRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIRTI 882
            :  ....:....|:.:::.... :||::.....|.:.|:||::|||:..|:||||..|.:..:|.
Mouse   750 F--CMMDLPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTF 812

  Fly   883 MKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEP 947
            .||...|::|.:|..:|||::|||.|:.|:|.:|.:|||:||:||.|:||..||:.|..|..|||
Mouse   813 NKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPLSVAESLKKGCTVEP 877

  Fly   948 EEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLP 1012
            |.|..||:|||||||||.:.|.|.|::||:.|||||:.||.|||.:||||||||||||:|.||||
Mouse   878 EGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLP 942

  Fly  1013 EPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTV 1077
            :.||.:||.|||.|:||||.:|.:|.:||.||..::||||:|||.|.|||||..||.||||||||
Mouse   943 KRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTV 1007

  Fly  1078 NTASRMESTGQPGKIHVSSATKAILDKFGT-FQMEQRGDVELKGKGTVTTYWLNSTSEGEARP-P 1140
            ||||||||||.|.:||||.:|..||..... :::|.||..|||||||..|:||.. .:|..:| |
Mouse  1008 NTASRMESTGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKGKGTEETFWLVG-KKGFTKPLP 1071

  Fly  1141 TP 1142
            .|
Mouse  1072 VP 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575	86/436 (20%)
		Protein Kinases, catalytic domain	616..885	CDD:473864	96/280 (34%)
		HNOBA	<891..939	CDD:462234	24/47 (51%)
		CYCc	918..1109	CDD:214485	121/191 (63%)
Gucy2f	NP_001007577.1	PBP1_sensory_GC_DEF-like	54..435	CDD:380594	86/438 (20%)
		Protein Kinases, catalytic domain	545..815	CDD:473864	96/279 (34%)
		HNOBA	<824..869	CDD:462234	23/44 (52%)
		CYCc	848..1040	CDD:214485	121/191 (63%)