DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3216 and Gucy1b2

DIOPT Version :9

Sequence 1:NP_726013.2 Gene:CG3216 / 37376 FlyBaseID:FBgn0034568 Length:1161 Species:Drosophila melanogaster
Sequence 2:XP_011243363.2 Gene:Gucy1b2 / 239134 MGIID:2660873 Length:829 Species:Mus musculus


Alignment Length:325 Identity:136/325 - (41%)
Similarity:185/325 - (56%) Gaps:53/325 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   850 CPPDLLELMEKCWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYANNLESLVEEK-- 912
            |.|.|..|.|.     :|.:...|.|..:..|      .:|:  |||:.......|...:|:|  
Mouse   483 CSPKLRSLQEL-----EESKMHLSDIAPHDTT------RDLI--LLNQQRLAEMELSCQLEKKKE 534

  Fly   913 -----TRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCARSSP 972
                 :..|::||::||.|||.:||..||.||..|..|...||.:.||.|||:|.||.:||...|
Mouse   535 ELRVLSNHLAIEKKKTETLLYAMLPEHVANQLKEGKKVAAGEFETCTILFSDVVTFTNICAACEP 599

  Fly   973 MDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMAL-------DI 1030
            :.:||.||.:||.|||:...:||||||||||||:||.|:|.| .:.||:.:|..||       ::
Mouse   600 IQIVNMLNSMYSKFDRLTNIHDVYKVETIGDAYMVVGGVPVP-VESHAQRVANFALGMRISAKEV 663

  Fly  1031 LRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVS 1095
            :..|:.     :|   ||||:|:|:|.|.|||||.|||.||||||||||||||||.|.|.|:|:|
Mouse   664 MNPVTG-----EP---IQIRVGIHTGPVLAGVVGDKMPRYCLFGDTVNTASRMESHGLPNKVHLS 720

  Fly  1096 SATKAILDKFGTFQMEQRGDVELKGKGTVTTYW----LNST-----------SEG-EARPPTPQI 1144
            ......|:..| |::..||::|:||||.:|||:    ||:|           ::| ||..|..|:
Mouse   721 PTAHRALENKG-FEIVTRGEIEVKGKGKMTTYFLIRNLNATEVEIMGRPSALADGKEASTPRNQV 784

  Fly  1145  1144
            Mouse   785  784

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3216NP_726013.2 PBP1_NPR_like 90..496 CDD:107368
ANF_receptor 107..479 CDD:279440
PKc_like 616..885 CDD:304357 9/34 (26%)
TyrKc 627..877 CDD:197581 8/26 (31%)
HNOBA <882..939 CDD:285003 19/63 (30%)
CYCc 918..1109 CDD:214485 100/197 (51%)
Guanylate_cyc 945..1131 CDD:278633 98/196 (50%)
Gucy1b2XP_011243363.2 HNOB 115..276 CDD:400167
HNOBA 380..566 CDD:400168 28/95 (29%)
Guanylate_cyc 572..754 CDD:306677 97/191 (51%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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