Protein Alignment CG3216 and gcy-36

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_510557.3
• Gene: gcy-36 / 191657
• WormBaseID: WBGene00001556
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 710
• Identity: 189/710 - (26%)
• Similarity: 295/710 - (41%)
• Gaps: 183/710 - (25%)

  Fly   483 GKFSVVAHYSGVHKVYSAVHGKKIHWPGGREEPPPDVPPCGFLGNSTDCVGNFSTIMYSVFGLLL 547
            ||.:::.||......:|.|....:.....||:                        ::.::|..
 Worm    34 GKENIINHYYSDADTFSLVDAVSVILKVTREQ------------------------VWEMYGCF- 73

  Fly   548 FLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEMGGMFGSKGGLQRLDVENISLQQFGIH- 611
                      |:|..|:       ..|    ||::..|..  ..||.|..||    ||..|..|
 Worm    74 ----------LIQYTME-------TGW----DDLIRSMSP--NLKGFLDNLD----SLHYFIDHV 111

  Fly   612 -----------------SGRASIASFTSLPPQVYTTIGQFKGE-RVAIKKVNVKKVD----LTPQ 654
                             .|..::..:|. .|.:|..:   ||. |.|.|:  |.|:|    :|.:
 Worm   112 VYKANLRGPSFRCEDNPDGTITLHYYTG-RPGLYPIV---KGVLREAAKR--VFKLDVSMTITGR 170

  Fly   655 LLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIH- 718
            ....::.|.....|..|.|:...::..:             |.::.|....::...|:::.|.|
 Worm   171 TQRSVQMATGERIEEHVIFLVKTLNTDQ-------------SNEEALGTAVVQHSNNYKIRLTHM 222

  Fly   719 DIVKGMNY----------------LHN---SDVAAHGK--LR---------------SCNCLIDG 747
            |.:....|                |:|   .|:.:.|.  :|               .|| .|:.
 Worm   223 DFISTFPYHMVVDQDCKIVQVGRELYNHIPKDLLSVGTPLMRIFEVTRPQIPLDFDSICN-FINA 286

  Fly   748 RFVLKISDFGLRTLTTPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCPATQRGDVYSFGIILEEI 812
            .|||::.       |||.:|.|:.|........|.|.| .....|....:|...:...|.::  :
 Worm   287 VFVLQVK-------TTPMEFQRNANKRAAQAIEASENL-YEDNNGALALSQSQHLKLKGQMM--L 341

  Fly   813 VNRGGPYQEARQQMDVHTILHKVRQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRS 877
            ::.||               |.:..|:.:...|      |:||:...:..|....: ||...|..
 Worm   342 MSSGG---------------HIMYLCSPYVTSI------PELLQYGLRLTAMPIHD-PTRDLILL 384

  Fly   878 NIRTIMKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAG 942
            |         :..:.|:...::..|||.:  :|...:.|.:||.:|:.||.::||..|||||..|
 Worm   385 N---------QQRLSDVEMNLQLEANNEQ--LENMAKDLEVEKGKTDALLREMLPPSVAQQLKQG 438

  Fly   943 DLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLV 1007
            ..||..|:...|:.|:|:..|.::....:|.|:|:.||:|::.|||:||....|||||:||:|:.
 Worm   439 LSVEAREYEEATVMFTDVPTFQQIVPLCTPKDIVHLLNELFTKFDRLIGIQKAYKVETVGDSYMS 503

  Fly  1008 VSGLPEPNGDKHAREIALMALDIL---RAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPH 1069
            |.|:|: ..|.|...|..:||.::   |.|.. .:.:.|   :.||.|:|||.|.|||||.|||.
 Worm   504 VGGIPD-LVDDHCEVICHLALGMVMEARTVCD-PITNTP---LHIRAGIHSGPVVAGVVGAKMPR 563

  Fly  1070 YCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWL 1129
            ||||||||||:|||||....|:||.|...|...:..|.|:.|.||.|::||||.:.||:|
 Worm   564 YCLFGDTVNTSSRMESHSPIGRIHCSENAKKCAESTGRFEFEPRGRVQIKGKGEMNTYFL 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575	5/17 (29%)
		Protein Kinases, catalytic domain	616..885	CDD:473864	59/310 (19%)
		HNOBA	<891..939	CDD:462234	16/47 (34%)
		CYCc	918..1109	CDD:214485	86/193 (45%)
gcy-36	NP_510557.3	HNOB	3..167	CDD:462233	37/190 (19%)
		HNOBA	217..435	CDD:462234	56/261 (21%)
		CYCc	415..604	CDD:214485	87/193 (45%)