Protein Alignment CG3216 and gcy-27

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_001255957.2
• Gene: gcy-27 / 191654
• WormBaseID: WBGene00001550
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 192/597 - (32%)
• Similarity: 307/597 - (51%)
• Gaps: 72/597 - (12%)

  Fly   572 MSWRVRPDDVLIEMGGMFGSKGGLQRLDVENISL--QQFGIHSGRASIASFTSLPPQVYTTIGQF 634
            |:|:|..:.:.|.:..  .:...:|| ::||.:.  :...:.|.|....|        |..||..
 Worm    33 MTWKVPKESLKIIVNK--NADARMQR-ELENRTAKDEANALTSRRRVFGS--------YALIGTQ 86

  Fly   635 KGERVAIKKVNVKKVDLTP---QLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGS 696
            :.|.:..::  :|.:|:|.   ..|:.:||   :.|:|...|.|..::....|:.||.....||:
 Worm    87 RAEFIQFRQ--IKHIDITNASLDFLYNLKQ---LKHDNLANFYGIQLNDDLNTMTILHALVERGT 146

  Fly   697 LKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGL--- 758
            |::...:....:|..|:.:.:.||:||:.|||.|.||.||.|.:..||||..:||||:.:|:
 Worm   147 LEEFCLDRDFGMDETFKSAFMRDILKGLQYLHLSPVAYHGHLHAATCLIDINWVLKIALYGVTNF 211

  Fly   759 -------RTLTTP--SDFVRDQNYYLKLLWIAPE---------LLPLTTIPGCCPATQRGDVYSF 805
                   ..:|.|  ||:...   |.:.:...||         .||...:.|    :::||:|..
 Worm   212 VCDNFDAENITMPDRSDYTIS---YAQYVCFPPEHIREYDATGKLPTRFVRG----SKQGDIYCV 269

  Fly   806 GIILEEIVNRGGPYQEARQQMDVHTILHKVRQ----------CNGFRPLIRERECPPD-LLELME 859
            |:|...::.|..||:          ::|.|.:          .:...|.|...|...| ||:..:
 Worm   270 GMIFYMMIEREDPYR----------LIHSVERPGSGLMMEILDHNLMPFISNNETQEDTLLDKCK 324

  Fly   860 KCWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTE 924
            :||..:.|:|||...:|:.|.........||:|.::...|:||:.||:||..::..|:|.:.:|.
 Worm   325 ECWNRDPEKRPTIENLRNAIAICYADSKGNLIDQMIRMNEKYADELETLVAARSADLALAQMQTM 389

  Fly   925 ELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRI 989
            .||.::||..:|:.|..|.:.....::|.|:.|..|..|..:..|..|.:|:.||||::..||.:
 Worm   390 RLLNEMLPASIAKDLKNGVIAPARSYASATVMFVQICDFIVILKRRPPKEVIGFLNDIFDQFDTV 454

  Fly   990 IGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRAVS-SFNLRHKPEYKIQIRIGM 1053
            |..:|.|||||.|:.|:|.||:|..|..:|..|:|.|:|:| ||:| |:.|.:...||:::|||.
 Worm   455 IKRHDAYKVETTGETYMVASGVPNENEGRHVFEVAEMSLEI-RAISLSYTLENDKNYKLRVRIGF 518

  Fly  1054 HSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVEL 1118
            |:|.:.|||:|.|.|.|||||||||.||||:|...|.:|..|..|..:|.....:::.:||.|.:
 Worm   519 HAGPIAAGVIGIKNPRYCLFGDTVNFASRMQSNCPPLQIQTSEITARMLLATHEYKLVKRGIVHV 583

  Fly  1119 KGKGTVTTYWLN 1130
            ||||.|..||||
 Worm   584 KGKGEVNCYWLN 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575
		Protein Kinases, catalytic domain	616..885	CDD:473864	79/303 (26%)
		HNOBA	<891..939	CDD:462234	16/47 (34%)
		CYCc	918..1109	CDD:214485	80/191 (42%)
gcy-27	NP_001255957.2	Protein Kinases, catalytic domain	75..338	CDD:473864	77/292 (26%)
		CYCc	383..573	CDD:214485	80/190 (42%)