Protein Alignment CG3216 and gcy-27

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_001255957.2
• Gene: gcy-27 / 191654
• WormBaseID: WBGene00001550
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 192/597 - (32%)
• Similarity: 307/597 - (51%)
• Gaps: 72/597 - (12%)

  Fly   572 MSWRVRPDDVLIEMGGMFGSKGGLQRLDVENISL--QQFGIHSGRASIASFTSLPPQVYTTIGQF 634
            |:|:|..:.:.|.:..  .:...:|| ::||.:.  :...:.|.|....|        |..||..
 Worm    33 MTWKVPKESLKIIVNK--NADARMQR-ELENRTAKDEANALTSRRRVFGS--------YALIGTQ 86

  Fly   635 KGERVAIKKVNVKKVDLTP---QLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGS 696
            :.|.:..::  :|.:|:|.   ..|:.:||   :.|:|...|.|..::....|:.||.....||:
 Worm    87 RAEFIQFRQ--IKHIDITNASLDFLYNLKQ---LKHDNLANFYGIQLNDDLNTMTILHALVERGT 146

  Fly   697 LKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGL--- 758
            |::...:....:|..|:.:.:.||:||:.|||.|.||.||.|.:..||||..:||||:.:|:
 Worm   147 LEEFCLDRDFGMDETFKSAFMRDILKGLQYLHLSPVAYHGHLHAATCLIDINWVLKIALYGVTNF 211

  Fly   759 -------RTLTTP--SDFVRDQNYYLKLLWIAPE---------LLPLTTIPGCCPATQRGDVYSF 805
                   ..:|.|  ||:...   |.:.:...||         .||...:.|    :::||:|..
 Worm   212 VCDNFDAENITMPDRSDYTIS---YAQYVCFPPEHIREYDATGKLPTRFVRG----SKQGDIYCV 269

  Fly   806 GIILEEIVNRGGPYQEARQQMDVHTILHKVRQ----------CNGFRPLIRERECPPD-LLELME 859
            |:|...::.|..||:          ::|.|.:          .:...|.|...|...| ||:..:
 Worm   270 GMIFYMMIEREDPYR----------LIHSVERPGSGLMMEILDHNLMPFISNNETQEDTLLDKCK 324

  Fly   860 KCWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTE 924
            :||..:.|:|||...:|:.|.........||:|.::...|:||:.||:||..::..|:|.:.:|.
 Worm   325 ECWNRDPEKRPTIENLRNAIAICYADSKGNLIDQMIRMNEKYADELETLVAARSADLALAQMQTM 389

  Fly   925 ELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRI 989
            .||.::||..:|:.|..|.:.....::|.|:.|..|..|..:..|..|.:|:.||||::..||.:
 Worm   390 RLLNEMLPASIAKDLKNGVIAPARSYASATVMFVQICDFIVILKRRPPKEVIGFLNDIFDQFDTV 454

  Fly   990 IGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRAVS-SFNLRHKPEYKIQIRIGM 1053
            |..:|.|||||.|:.|:|.||:|..|..:|..|:|.|:|:| ||:| |:.|.:...||:::|||.
 Worm   455 IKRHDAYKVETTGETYMVASGVPNENEGRHVFEVAEMSLEI-RAISLSYTLENDKNYKLRVRIGF 518

  Fly  1054 HSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVEL 1118
            |:|.:.|||:|.|.|.|||||||||.||||:|...|.:|..|..|..:|.....:::.:||.|.:
 Worm   519 HAGPIAAGVIGIKNPRYCLFGDTVNFASRMQSNCPPLQIQTSEITARMLLATHEYKLVKRGIVHV 583

  Fly  1119 KGKGTVTTYWLN 1130
            ||||.|..||||
 Worm   584 KGKGEVNCYWLN 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357	79/303 (26%)
		TyrKc	627..877	CDD:197581	76/284 (27%)
		HNOBA	<882..939	CDD:285003	18/56 (32%)
		CYCc	918..1109	CDD:214485	80/191 (42%)
		Guanylate_cyc	945..1131	CDD:278633	83/187 (44%)
gcy-27	NP_001255957.2	PKc_like	75..338	CDD:304357	77/292 (26%)
		CYCc	383..573	CDD:214485	80/190 (42%)
		Guanylate_cyc	411..595	CDD:278633	81/184 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920