Protein Alignment CG3216 and gcy-11

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_001359843.1
• Gene: gcy-11 / 181745
• WormBaseID: WBGene00001537
• Length: 1168
• Species: Caenorhabditis elegans
• Alignment Length: 1186
• Identity: 330/1186 - (27%)
• Similarity: 534/1186 - (45%)
• Gaps: 277/1186 - (23%)

  Fly   118 EINKVFLKP---HNITLLKKKGSYPSCSGARAPGLAADMYFQDDVIAFIGPA--CAFALEPVARL 177
            :|...|..|   .|.::.::.|:|.|   :....:.||....|.::..:|..  |    :.:|.|
 Worm    69 DITVEFFDPTVQGNFSIGRQDGNYMS---SMLDIMLADTKKNDGLLGVVGVENDC----KEIAAL 126

  Fly   178 A-AYWNKPIITGMGDQPPSSEGELTVTSGILGRIHKWKNENTGMFKDKSKYPTLTRMSYCQCRLI 241
            | ||....::....||    .||..:.|.                       |..:||..|....
 Worm   127 AQAYDASSLLVNCEDQ----VGESQMPSS-----------------------TALQMSSTQGGKY 164

  Fly   242 LVFASVIRQFNWNHVALLVDRSELFSWTVGKNLEY------GLRQEGL-LSFVKE---------- 289
            ..||.:.:...||::|::     .|......::.|      .|..|.: |.|||:
 Worm   165 RAFAKLAKSVGWNNLAVI-----NFVEDGPADISYHDQLLDALSAESISLDFVKKGGFSSTITSA 224

  Fly   290 -LNGNE---EEVYENYLKDASMYARVVILSVRGVLVRKFMLAAHSLG-MTNGEWVFLDVEIFQSE 349
             ..|.|   :.:.|.|:| ..:|..|:.|.|.|..   ||.|..::| :..|::..:.:...:|:
 Worm   225 MFTGLESVIDVILETYMK-TRIYVIVLDLPVSGTF---FMNAMSTMGLLETGKYFVVMMSSIESD 285

  Fly   350 ---YWG-------------DKGWEMKDEHDAKARKAYEALLRVSLLQPTSPKF-QDFAD------ 391
               |:|             |.|..     ||..|:.|.:.:..:    ..|.: :||:|
 Worm   286 AANYFGFNVNRGNMIFKTIDYGIS-----DADIRQYYRSFMYFT----DVPHYTKDFSDEWTSFQ 341

  Fly   392 ----------------NVRENAL------YDYNYTFGEGEEVNFFIGAFYDGVYLLGMALNETLT 434
                            |.:...:      .|..|.:.|...:   :.| ||    ||..|:||:.
 Worm   342 KRVDGDASKTFCPPMCNTKAKGIANNDPWSDDAYWYSESPSI---VDA-YD----LGRLLSETVK 398

  Fly   435 EGGD--IRDGVNITRRMWNRTFEGITGHV-RIDDNGDRDADYSI---LDLDPING-----KFSVV 488
            ..|.  :||..::.:.|..|....:.|:| :.:.||....:|.:   ......||     :::.:
 Worm   399 VHGASLLRDPESLVQTMSGRGVTSLLGYVTKFNTNGVSQREYILWAPQQASSSNGPIPLPEWATL 463

  Fly   489 A---------HYSGVHKVYSAV---HGKKIHWPGGREEPPPDVPPCGFLGNSTDC---VGNFS-- 536
            |         :||.:.|..:.:   :|          |.|...|.|||  |:..|   :.|.|
 Worm   464 AARMLPDGKGNYSIIWKNLTQLGIFNG----------ELPQSKPECGF--NNELCPAGIRNLSEL 516

  Fly   537 ---TIMYSVFGLLLFLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEMGGMFGSKGGLQRL 598
               .|...|..:|:.:|    ||..:.:.:...:.|.:..:.|                   .|.
 Worm   517 EIIVIAVCVVAILILVG----VIAYIARWIAYERRLESSYFLV-------------------HRK 558

  Fly   599 DVENISLQQFGIHSGRASIASFTSLPPQ-------------VYTT-------------------- 630
            .|:.:.:.:||...|.:.|.|..|:..|             .||.
 Worm   559 HVQLVDMTKFGSSRGGSMIQSAMSMRSQYEDSGPVGGATMNFYTNGIRKAAIRRNQMQRSDKGPA 623

  Fly   631 -------------IGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPR 682
                         :.:::...|.::|:|..::.||.::..||....:.:|||..||.|    |..
 Worm   624 ANRDEWLEIVDWHLAKYENTLVTVRKINKTQLKLTREMKQEIDLLMNETHENLNRFFG----LIN 684

  Fly   683 PTVLILT--EYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLH-NSDVAAHGKLRSCNCL 744
            .:.||.|  .|..|.||.|:|.|:.:.||..|::|.:.|:|||:.:|| .|.:..||.|:|.||:
 Worm   685 ESDLIFTIHSYGPRKSLMDLLRNDDLRLDRMFKVSFVEDVVKGLQFLHEGSKIGYHGNLKSSNCI 749

  Fly   745 IDGRFVLKISDFGLRTL------TTPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCPATQ--RGD 801
            :|..:.:|:|::|:..:      :.|.|          |||.|||::....:.......:  :.|
 Worm   750 VDAYWRIKLSNYGMEQIRVEEPESKPDD----------LLWFAPEIIRRYAVKHDLSKLELAKAD 804

  Fly   802 VYSFGIILEEIVNRGGPYQEARQQMDVHTILHKVRQCNG---FRPLIR-ERECPPDLLELMEKCW 862
            :||..|:|.||..|.||:.:  ..:|...|:.:::..:|   .||.|. ..:.|..|..::||||
 Worm   805 IYSLAIVLYEIYGRQGPFGD--DLLDSDEIIEQLKFPDGGALTRPDIHLITKAPYPLASVVEKCW 867

  Fly   863 ADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELL 927
            .::...||:...:|..::.:.||...|:.|:::|.:::|.||||.:::|:|.||..|::|.|.||
 Worm   868 VEDPASRPSIKKVRELLKPLSKGLKGNIADNIMNLLDRYRNNLEDVIKERTEQLEDERKRNESLL 932

  Fly   928 YQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGF 992
            .|:||:.||..|..|..|:.|.:.||:||||||||||.|.::|:|:.|||.||:||:.||.||..
 Worm   933 LQLLPKSVANSLKNGQPVDAEFYDSVSIYFSDIVGFTALSSKSTPLQVVNMLNNLYTNFDTIIDK 997

  Fly   993 YDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGS 1057
            :|.||||||||||:.||||||.|...||.|:|..:|::|.::.:|.:.|.|:.|:::|||.|:|.
 Worm   998 FDCYKVETIGDAYMFVSGLPEVNSYLHAGEVASASLELLDSIKTFTVSHCPDEKLRLRIGNHTGP 1062

  Fly  1058 VCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKG 1122
            |..||||.:||.||||||||..|:.|||:|:|.:|.:||....::.|.|.:..|||..:.||.|.
 Worm  1063 VVTGVVGIRMPRYCLFGDTVIIANMMESSGEPMRIQISSDAYELILKCGGYVTEQREKIVLKNKL 1127

  Fly  1123 TVTTYWLNSTSEGEAR 1138
            .|.|||:|..|: :||
 Worm  1128 EVMTYWMNDYSK-DAR 1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368	94/470 (20%)
		ANF_receptor	107..479	CDD:279440	89/439 (20%)
		PKc_like	616..885	CDD:304357	84/329 (26%)
		TyrKc	627..877	CDD:197581	79/297 (27%)
		HNOBA	<882..939	CDD:285003	24/56 (43%)
		CYCc	918..1109	CDD:214485	99/190 (52%)
		Guanylate_cyc	945..1131	CDD:278633	97/185 (52%)
gcy-11	NP_001359843.1	Periplasmic_Binding_Protein_type1	<234..452	CDD:385651	48/238 (20%)
		PKc_like	640..890	CDD:389743	78/265 (29%)
		CYCc	923..1116	CDD:214485	99/192 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920