Protein Alignment CG3216 and gcy-33

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_001256392.1
• Gene: gcy-33 / 179644
• WormBaseID: WBGene00001553
• Length: 947
• Species: Caenorhabditis elegans
• Alignment Length: 652
• Identity: 161/652 - (24%)
• Similarity: 264/652 - (40%)
• Gaps: 181/652 - (27%)

  Fly   617 IASFTSLPPQVYTTIGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLP 681
            :...|||..:..:|..|: .|.|            .||:...|.:.....:|......|.
 Worm    25 VQKLTSLSEKSVSTHDQY-SEHV------------VPQMFKAIHEITGTPYEQIGVLAGR----- 71

  Fly   682 RPTVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRS----CN 742
                 ...::..|....|::         |.......|.:||::.:|.....::.|||:    |.
 Worm    72 -----FFVQFLIRNGYGDLM---------NVMGRRFSDFIKGLDNIHEYFRFSYPKLRAPSFYCK 122

  Fly   743 C------------------------LID--------------------GRF---VLKIS--DFGL 758
            .                        |::                    |||   |||||  :.||
 Worm   123 SESEDGLILHYRSRRTGYLSYVIGQLVELARVFYQLDIGIQVLKKKEKGRFTFVVLKISFDNVGL 187

  Fly   759 RTLTTPSDFVRDQNYY---------------------LKLLWIAPELLPLTTIPGCCPATQRGDV 802
            .......:.|::.|.|                     |::|.....||.|      .|..|
 Worm   188 GQDLKLKERVKNLNEYLPVDTKSFLQMFPFHIAFNKKLEILMAGQGLLNL------MPNIQ---- 242

  Fly   803 YSFGIILEEIVNRGGP-YQEARQQMDVHTILHKVRQCNGFRPLIRERE---------CPPDLLEL 857
               |:::.::.:...| .:...:.:.||.  :.|.|.....|::::.|         ...|.:.|
 Worm   243 ---GLLMTDVFDLQRPCIKFTAEGIMVHQ--NCVFQIESLHPVVKQTEENITVQINDITEDKVSL 302

  Fly   858 MEKCWADNQ---EERPTFSTIRSNIRTIMKG------FCENLMD--DLLNRMEQYANN------- 904
            .:|...||:   |..| :.|:|..| |::|.      ....::|  |.:.:|..|.|:
 Worm   303 EKKTVMDNEYGLESLP-YVTLRGPI-TVLKSSETFLLLATCVVDTLDTMFKMGLYLNDFGESDCN 365

  Fly   905 -------------LESLVE----------EKTRQLSLEKQRTEELLYQILPRPVAQQLM-AGDLV 945
                         |::::|          |.||::|..|:....||.|::|..|||.:| :|.:.
 Worm   366 REIIMATIQKSDTLKTMLENEKRRSEVLTEMTREISEAKKTARTLLTQMMPYEVAQTMMRSGSVD 430

  Fly   946 EPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSG 1010
            ..|.|..|:|.|..:..|:::.......:|||.||.:||..|.|:..:.||||||||::|::.:|
 Worm   431 HCEAFECVSIGFIRVCDFSKISLFIEAFEVVNLLNTIYSHLDSIVDTHGVYKVETIGESYMISAG 495

  Fly  1011 LPEPNGDKHAREIALMALDILRAVSSFNLR-HKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFG 1074
            .|. ..|..|..::...|:::..:.||..: |....|:.|:.|:.:|.|..||||.:.|.|||||
 Worm   496 CPY-RDDYDAEMVSDCCLEMVSHIKSFEYQSHDAVKKVLIKCGIFTGPVVGGVVGVRTPRYCLFG 559

  Fly  1075 DTVNTASRMESTGQ-PGKIHVSSATKAILDK--FGTFQMEQRGDVELKGKGTVTTYWLNSTSEGE 1136
            |||||||||||:.| |..|.:...||..::|  .|.|:::.:|:|.:||||.:..|.:.. .:|.
 Worm   560 DTVNTASRMESSNQTPMTIQIGQRTKDRVEKQASGAFRIKPKGNVFVKGKGDMRVYEIEK-KKGR 623

  Fly  1137 AR 1138
            ||
 Worm   624 AR 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575
		Protein Kinases, catalytic domain	616..885	CDD:473864	63/354 (18%)
		HNOBA	<891..939	CDD:462234	19/79 (24%)
		CYCc	918..1109	CDD:214485	75/195 (38%)
gcy-33	NP_001256392.1	HNOB	2..164	CDD:462233	24/170 (14%)
		HNOBA	204..423	CDD:462234	46/235 (20%)
		CYCc	402..598	CDD:214485	76/196 (39%)
		COG5134	<595..744	CDD:227463	11/32 (34%)