Protein Alignment CG3216 and LOC1280524

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: XP_061518472.1
• Gene: LOC1280524 / 1280524
• VectorBaseID: AGAMI1_000821
• Length: 1259
• Species: Anopheles gambiae
• Alignment Length: 1140
• Identity: 418/1140 - (36%)
• Similarity: 589/1140 - (51%)
• Gaps: 197/1140 - (17%)

  Fly    88 VYNVGVLMASHLDSPFDLERCGP------AVDLALDEINKVFLKPH--------------NITLL 132
            |:.||.|..|. ..|.|.....|      |:.||:.|:|..:...|              .:|.:
Mosquito    68 VFTVGYLTGSQ-RRPGDRVYARPGLQISGAITLAMTEVNDRYFSQHGHELRFEVAETYGEEVTSI 131

  Fly   133 KKKGSYPSCSGARAPGLAADMYFQDDVIAFIGP--ACAFALEPVARLAAYWNKPIITGMGDQPPS 195
            :|               .||::.: ||||::||  .|...    .|:||.:|.|:|:.....
Mosquito   132 RK---------------TADLWTR-DVIAYLGPQETCVHE----GRMAAAFNLPMISYFCTH--- 173

  Fly   196 SEGELTVTSGILGRIHKWKNENTGMFKDKSKYPTLTRMSYCQCRLILVFASVIRQFNWNHVALLV 260
                               ||.:    :|..:||..|......::.....|::..:||..|:.|.
Mosquito   174 -------------------NETS----NKKHFPTFARTRPPDLQISKSVVSLLLAYNWTQVSFLY 215

  Fly   261 ---DRSELFSWTVGKNLEYGLRQEGLLSFVKELNGNEEEVY-------------ENYLKDASMY- 308
               |..||.:  |.:.|:..||...:.  ::.: |...::|             |:..:|..:|
Mosquito   216 RASDNGELDA--VAETLKTTLRTANIR--IRSV-GTWTDIYHHGYSSNPFERLVEDTYEDTRIYL 275

  Fly   309 ---------ARVVILSVRGVLVRKFMLAAHSLGMTNGEWVFLDVEIFQSEYWGDKGWEMKDEHDA 364
                     ..:|.|..||:|.|             |::..:.|:|              |::||
Mosquito   276 VLGYHYEHIGLLVSLRRRGLLDR-------------GDYFVVGVDI--------------DQYDA 313

  Fly   365 KARKAY--------------EALLRVSLLQPTSP-KFQDFADNVREN-ALYDYNYT-----FGEG 408
            .....|              ||......:.|::| :|::||..|.:. .|..:||.     ||..
Mosquito   314 ALPTKYMHGLLQTTPDPDAVEAFRHYLGIVPSAPVRFEEFAVKVNKYLELPPFNYRNALIFFGGV 378

  Fly   409 EEVNFFIGAFYDGVYLLGMALNETLTEGGDIRDGVNITRRMWNRTFEGITGH-VRIDDNGDRDAD 472
            :::.......||.|:|...||.:.|..||..::|..|...:..|.:....|: |.||:|||...:
Mosquito   379 KQIRAEAAYLYDAVHLYANALMQVLLSGGSPKNGSAIIEAIKGRAYISAMGYLVHIDENGDATGN 443

  Fly   473 YSILDLDPIN-------------GKFSVVAHYSGVHKVYSAVHGKKIHWPGGREEPPPDVPPCGF 524
            |:||...|:.             |:||.........|:........|.|.|  ..||...|.|||
Mosquito   444 YTILARKPVPSTGTTNQYGLFPIGRFSSPTVDRIPFKIQEIRLFDTIDWVG--SGPPVAEPRCGF 506

  Fly   525 LGNSTDCVGNFSTIMYSVF-GLLLFLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEMGGM 588
            .|..  |:.....|...:. |.||.||:|.||   |.:..:..:||:::.|:|  |...|:|...
Mosquito   507 RGEK--CISYTGEITGGIAGGALLLLGVVSLV---LYRNWRYEQELDSLLWKV--DFREIQMHEN 564

  Fly   589 FGSKGGLQRLDVENISLQQFGIHSGRASIASFTSLP---PQVYTTIGQFKGERVAIKKVNVKKVD 650
            .....| |::......|    |.:.:.|::|...|.   ..::|.||.:||:..|||||..|.:|
Mosquito   565 EKETAG-QKMTRSTHPL----IRTSQVSLSSNPDLDFRYSTIFTPIGLYKGQLYAIKKVKKKSID 624

  Fly   651 LTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIELDWNFRMS 715
            :|.::..|:|..||:.|:|...|:|||.|  .|.:.|:|:||:|||||||||||.::||..|..|
Mosquito   625 ITREMKKELKLLRDMRHDNLNAFIGACTD--PPNICIITDYCNRGSLKDVLENEDVKLDNMFTAS 687

  Fly   716 LIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQNYYL----- 775
            ::.||::||.|||:|.:..||.||:.|||||.|:|:|:|||||......|:.|.|:...|
Mosquito   688 MVADILRGMIYLHDSPLRFHGSLRTSNCLIDSRWVVKLSDFGLFAFKQGSEEVPDEKEKLEEKCQ 752

  Fly   776 KLLWIAPELL---PLTTIPGCCPATQRGDVYSFGIILEEIVNRGGPYQEAR-QQMD-VHTILHKV 835
            |||:.|||||   |..|:||    |.:||||||||:|.||..|.||:.|.. ..|: :..:|:.:
Mosquito   753 KLLYRAPELLRAGPTATVPG----TPKGDVYSFGIVLYEIFTRRGPFGEIECTPMECLKRVLNPL 813

  Fly   836 RQCNGFRPLIRERECPPDLL-ELMEKCWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRME 899
            .....|||.|:..|...|.: :.:::|||:..|:||.|.|||:.:|.:.||...|:.|:::..||
Mosquito   814 DPNTPFRPAIQPLETSFDCVRDCLKECWAERPEDRPDFKTIRNRLRVLRKGMRPNIFDNMMAMME 878

  Fly   900 QYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFT 964
            :||||||.||:|:|.||..||::||.||.::||||||:||..|..||.|.:..||||||||||||
Mosquito   879 KYANNLEQLVDERTDQLQEEKKKTEALLLEMLPRPVAEQLKRGHKVEAESYDLVTIYFSDIVGFT 943

  Fly   965 ELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALD 1029
            .:.|.|:|:.||:||||||:.||.|||.|||||||||||||:||||||..||..||.|||.|:|.
Mosquito   944 SMSAESTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPIRNGLIHAAEIASMSLQ 1008

  Fly  1030 ILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHV 1094
            :|.||:.|.:||:|..::.:|||:|||.|||||||.|||.||||||||||||||||||||.|||.
Mosquito  1009 LLEAVAEFKVRHRPNDRLYLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGQPLKIHC 1073

  Fly  1095 SSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWL 1129
            |..||.|||..|.:|.::||.|.:||||...|:||
Mosquito  1074 SLQTKEILDSLGGYQFQERGLVPMKGKGDQRTFWL 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575	106/493 (22%)
		Protein Kinases, catalytic domain	616..885	CDD:473864	123/282 (44%)
		HNOBA	<891..939	CDD:462234	27/47 (57%)
		CYCc	918..1109	CDD:214485	127/190 (67%)
LOC1280524	XP_061518472.1	None