Protein Alignment CG3216 and LOC1269185

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: XP_061497707.1
• Gene: LOC1269185 / 1269185
• VectorBaseID: AGAMI1_001998
• Length: 1357
• Species: Anopheles gambiae
• Alignment Length: 1096
• Identity: 464/1096 - (42%)
• Similarity: 633/1096 - (57%)
• Gaps: 135/1096 - (12%)

  Fly   141 CSGARAPGLAADMYFQDDVIAFIGPACAFALEPVARLAAYWNKPIITGMGDQPPSSEGELTVTSG 205
            ||.......|.|::.:.....|.||.|.:.:.|:||.::.|..|:|                |||
Mosquito   190 CSSTYGALGAFDIFLKRKPDVFFGPICDYVIAPIARYSSVWGIPLI----------------TSG 238

  Fly   206 ILGRIHKWKNENTGMFKDKS-KYPTLTRMSYCQCRLILVFASVIRQFNWNHVALLVDRSELFSWT 269
            .|          |..|..|: .|.|||||........|:...:.|.:||...|.|...   |...
Mosquito   239 GL----------TEAFTLKAPHYRTLTRMMGNYHAFGLMMREIHRHYNWTIQAYLYHE---FDEK 290

  Fly   270 VGKNLEYGLRQEGLLSFVKELNGNE-------EEV--YENYLK---------DASMYAR---VVI 313
            .|:.  :......:.|..:.:.|||       ||.  |.:||:         ...:|.|   |||
Mosquito   291 SGRG--FTDCSMAITSINRAIGGNETSSGTFDEETAKYADYLRLLRNIKKRARIHLYRRDLVVVI 353

  Fly   314 LSVRGVLVRKFMLAAHSLGMTN-GEWVFLDVEIFQS-EYWGDKGWEMK---DEHDAKARKAYEAL 373
            :......:|:.||||..|.|.| ||:||.::|||.| .......|..|   ||.:.||::|:.||
Mosquito   354 MCASPSTIREIMLAAAELNMVNSGEYVFFNIEIFGSMTATKQPPWYAKNDTDERNQKAKEAFTAL 418

  Fly   374 LRVSLLQPTSPKFQDFADNVRENALYDYNYTFGEGEEVNFFIGAFYDGVYLLGMALNETLTEGGD 438
            |:|...:|...:::.|:..|:|.....||:|:.|.|.|:.|:.||||.|.|...|||:::.:.|.
Mosquito   419 LQVVAREPEDEEYRQFSKEVKELTKTKYNHTYAEDEPVSTFVTAFYDAVLLYAYALNDSIAQLGV 483

  Fly   439 IR------DGVNITRRMWNRTFEGITGHVRIDDNGDRDADYSILDLDPINGKFSVVAHY---SGV 494
            .|      :|.::.:.||.|:|:||||:|.||.||||.::||:|||:|..|.|.|||:|   .|:
Mosquito   484 ERALRQPINGTHLAQLMWGRSFKGITGNVTIDSNGDRISNYSLLDLNPETGLFEVVANYYYGGGL 548

  Fly   495 HKVYSAVHGKKIHWPGGREEPPPDVPPCGFLGNSTDCVGNFSTIMYSVFGLLLFLGLVFLVICLL 559
                ..|.||.|||.|.|.:.|||.|.|||.|:.  |..| |...|::..|:|.:.:|.:.|..:
Mosquito   549 ----QFVEGKAIHWAGDRTKAPPDRPTCGFDGSL--CPDN-SLPGYAILSLVLGVCVVCMGIASI 606

  Fly   560 --QKQMKLSKELNNMSWRVRPDDVLIEMGGMFGSKGGLQRLDVENISLQQFGIHSGRASIAS--F 620
              .:..||..|:|:|:|:|.|:||| ......|.:|...       |:.:.|   .:|:|.|  .
Mosquito   607 VGYRHYKLEAEINSMTWKVNPNDVL-SCNPSRGHRGSFH-------SMVKRG---SQATIYSEDL 660

  Fly   621 TSLP--PQVYTTIGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPRP 683
            .|||  .|:|...|.:||.:|||||:||:.:.||..|:.|.|:.:|:.|::.|||.|||:|| .|
Mosquito   661 NSLPGDRQIYIHFGFYKGCKVAIKKINVQNLSLTRSLMLEFKRMKDIQHDHLVRFYGACLDL-HP 724

  Fly   684 TVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGR 748
            ...||||||.:|||:|:||||.|:|||.|::||:|||||||.:||::|:.:||.|:|.||::|.|
Mosquito   725 EPFILTEYCPKGSLQDILENETIKLDWMFKISLMHDIVKGMAFLHSTDLHSHGSLKSSNCVVDSR 789

  Fly   749 FVLKISDFGLRTLTTPSD--FVRDQNYYLKLLWIAPELLPLTTIPGCCPA-TQRGDVYSFGIILE 810
            ||||::||||..|...:|  .:....|:.||||.|||||   ..|.|.|| :|:|||||||||::
Mosquito   790 FVLKVTDFGLHQLRRSTDDADIESYAYWQKLLWTAPELL---RDPQCPPAGSQKGDVYSFGIIIQ 851

  Fly   811 EIVNRGGPYQEARQQMDVHTILHKVRQCNG-----FRPLIRERECPPDLLELMEKCWADNQEERP 870
            |||:|.||:....::.....|:..||...|     |||.:.|... .|:..:|.|||::...:||
Mosquito   852 EIVSRQGPFYLGTEEKSPKEIIKLVRDGPGILDAPFRPKVDESSY-EDVNNIMIKCWSEEPTDRP 915

  Fly   871 TFSTIRSNIRTIMK-GFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRP 934
            .||.:::.||.|.| ....|::|:||.||||||||||:||:|:|:....||::.||||||:||:.
Mosquito   916 DFSGLKTIIRKINKENESGNILDNLLQRMEQYANNLEALVDERTQDYFEEKRKCEELLYQLLPKS 980

  Fly   935 VAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVE 999
            ||.||:.|..|..|.:..||||||||||||.:.|:|:||.||:.|||||:.||.|:..:||||||
Mosquito   981 VAAQLIMGKSVIAETYDQVTIYFSDIVGFTSISAQSTPMQVVDLLNDLYTCFDSIVENFDVYKVE 1045

  Fly  1000 TIGDAYLVVSGLPEPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVG 1064
            ||||||:||||||..||:.|||||:.|||.:|.||..|.:||:|..::::|||:|||...|||||
Mosquito  1046 TIGDAYMVVSGLPVRNGNLHAREISRMALRLLAAVYKFTIRHRPNEQLRLRIGLHSGPCVAGVVG 1110

  Fly  1065 KKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWL 1129
            .|||.||||||||||||||||.|:..|||||..||.:||.||||.:.:||.|.:||||.:.||||
Mosquito  1111 LKMPRYCLFGDTVNTASRMESNGEALKIHVSHTTKLLLDTFGTFDLTERGLVPMKGKGEMLTYWL 1175

  Fly  1130 N-STSEGEARPPTPQ-----------------------ILTTDEVPF------PLL 1155
            | ..:|..|..|.|.                       :|.||.||.      |||
Mosquito  1176 NGERTEAIAAAPLPNGLKVMSPAGTSPASIMASRNGPTLLATDSVPASDPQQQPLL 1231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575	127/395 (32%)
		Protein Kinases, catalytic domain	616..885	CDD:473864	133/281 (47%)
		HNOBA	<891..939	CDD:462234	29/47 (62%)
		CYCc	918..1109	CDD:214485	121/190 (64%)
LOC1269185	XP_061497707.1	None