DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG3216 and Adcy9

DIOPT Version :9

Sequence 1:NP_726013.2 Gene:CG3216 / 37376 FlyBaseID:FBgn0034568 Length:1161 Species:Drosophila melanogaster
Sequence 2:XP_011244107.1 Gene:Adcy9 / 11515 MGIID:108450 Length:1372 Species:Mus musculus


Alignment Length:264 Identity:79/264 - (29%)
Similarity:127/264 - (48%) Gaps:45/264 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   914 RQLSLEKQRTEELLYQILPRPVAQQLM-AGD-----------------------------LVEP- 947
            :.|.:||...|.:::.::||.:|..|| .||                             ...| 
Mouse   321 KDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPF 385

  Fly   948 --EEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSG 1010
              ::...|:|.|:||||||::.|..|...:|..||||:..|||:.......|:.|:||.|..|:|
Mouse   386 KMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEQTKCEKISTLGDCYYCVAG 450

  Fly  1011 LPEPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGD 1075
            .|||..| ||.....|.|.:::|:..| .:.|.| .:.:|:|:|:|:|..|::|.:...:.::.:
Mouse   451 CPEPRAD-HAYCCIEMGLGMIKAIEQF-CQEKKE-MVNMRVGVHTGTVLCGILGMRRFKFDVWSN 512

  Fly  1076 TVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVT-------TYWLNSTS 1133
            .||.|:.||..|..||:|:|.||...||  ..::||....:|..|:..|.       ||.::...
Mouse   513 DVNLANLMEQLGVAGKVHISEATAKYLD--DRYEMEDGRVIERLGQSVVADQLKGLKTYLISGQR 575

  Fly  1134 EGEA 1137
            ..|:
Mouse   576 AKES 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3216NP_726013.2 PBP1_NPR_like 90..496 CDD:107368
ANF_receptor 107..479 CDD:279440
PKc_like 616..885 CDD:304357
TyrKc 627..877 CDD:197581
HNOBA <882..939 CDD:285003 7/24 (29%)
CYCc 918..1109 CDD:214485 70/223 (31%)
Guanylate_cyc 945..1131 CDD:278633 67/195 (34%)
Adcy9XP_011244107.1 MFS <134..260 CDD:391944
Guanylate_cyc 385..573 CDD:306677 66/192 (34%)
Guanylate_cyc 1069..1260 CDD:306677
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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