Protein Alignment CG3216 and Adcy6

DIOPT Version :10

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: XP_006520366.3
• Gene: Adcy6 / 11512
• MGIID: 87917
• Length: 1254
• Species: Mus musculus
• Alignment Length: 640
• Identity: 153/640 - (23%)
• Similarity: 240/640 - (37%)
• Gaps: 213/640 - (33%)

  Fly   535 FSTIMYSVFGLLLFLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEMGGMFGSKGGLQRLD 599
            :||::..::..:..|.||.::||                       .:...|..|..  .||||.
Mouse   779 YSTLILGIYAAIFLLLLVTVLIC-----------------------AVCSCGSFFPK--ALQRLS 818

  Fly   600 VENISLQQFGIHSGRASIASFTSLPPQVYTTIGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARD 664
             .||...:  :||  .::..|:.|...:......|......|:....:.::|||         .|
Mouse   819 -RNIVRSR--VHS--TAVGIFSVLLVFISAIANMFTCNHTPIRTCAARMLNLTP---------AD 869

  Fly   665 VSHENTVRFVGAC----------IDLP-----RPTVLILTEYCSRGSLKDVLENEAIELDWNFRM 714
            |:         ||          :|.|     .|| ....||                ...|..:
Mouse   870 VT---------ACHLQQLNYSLGLDAPLCEGTAPT-CSFPEY----------------FVGNVLL 908

  Fly   715 SLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQNYYLKLLW 779
            ||:...|    :||.|.:   |||..       .|:|..:...|..|..|:...  .||.| ||.
Mouse   909 SLLASSV----FLHISSI---GKLAM-------TFILGFTYLVLLLLGPPAAIF--DNYDL-LLG 956

  Fly   780 IAPELLPLTTIPGC-CPATQRGDV-YSFGIILEEIVNRGGPYQEARQQMDVHTILHKVRQCNGFR 842
            :........|..|. |||..|..: |...:||  :|.....|..|:|
Mouse   957 VHGLASSNETFDGLDCPAVGRVALKYMTPVIL--LVFALALYLHAQQ------------------ 1001

  Fly   843 PLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYANNLES 907
                                            :.|..|.           |.|.::
Mouse  1002 --------------------------------VESTARL-----------DFLWKL--------- 1014

  Fly   908 LVEEKTRQLSLEKQRTEE-------LLYQILPRPVAQQLMA----GDLVEPEEFSSVTIYFSDIV 961
                   |.:.||:..||       ||:.|||:.||...:|    .|.:..:....|.:.|:.|.
Mouse  1015 -------QATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIA 1072

  Fly   962 GFT----ELCARSSPMDVVNFLNDLYSTFDRIIG---FYDVYKVETIGDAYLVVSGLPEPNGDKH 1019
            .|:    ||.|.:..::.:..||::.:.||.||.   |..:.|::|||..|:..|||.....|:.
Mouse  1073 NFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQV 1137

  Fly  1020 AR-------EIALMALDILRAVS--SFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGD 1075
            .|       :.|:..::.::.::  |||       ..|::||::.|.|.|||:|.:.|.|.::|:
Mouse  1138 GRSHITALADYAMRLMEQMKHINEHSFN-------NFQMKIGLNMGPVVAGVIGARKPQYDIWGN 1195

  Fly  1076 TVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWLN 1130
            |||.:|||:|||.|.:|.|::....:|...| :|:|.||.|::||||.:|||:||
Mouse  1196 TVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG-YQLECRGVVKVKGKGEMTTYFLN 1249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_GC-like	90..501	CDD:380575
		Protein Kinases, catalytic domain	616..885	CDD:473864	52/285 (18%)
		HNOBA	<891..939	CDD:462234	14/54 (26%)
		CYCc	918..1109	CDD:214485	67/217 (31%)
Adcy6	XP_006520366.3	AC_N	83..454	CDD:318454
		Guanylate_cyc	456..640	CDD:425528
		Adcy_cons_dom	668..755	CDD:461877
		Guanylate_cyc	1056..1250	CDD:425528	68/202 (34%)