DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3216 and ADCY9

DIOPT Version :9

Sequence 1:NP_726013.2 Gene:CG3216 / 37376 FlyBaseID:FBgn0034568 Length:1161 Species:Drosophila melanogaster
Sequence 2:XP_005255136.1 Gene:ADCY9 / 115 HGNCID:240 Length:1372 Species:Homo sapiens


Alignment Length:265 Identity:80/265 - (30%)
Similarity:128/265 - (48%) Gaps:45/265 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   914 RQLSLEKQRTEELLYQILPRPVAQQLM-AGD-----------------------------LVEP- 947
            :.|.:||...|.:::.::||.:|..|| .||                             ...| 
Human   321 KDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPF 385

  Fly   948 --EEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSG 1010
              ::...|:|.|:||||||::.|..|...:|..||||:..|||:.......|:.|:||.|..|:|
Human   386 KMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAG 450

  Fly  1011 LPEPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGD 1075
            .|||..| ||.....|.|.:::|:..| .:.|.| .:.:|:|:|:|:|..|::|.:...:.::.:
Human   451 CPEPRAD-HAYCCIEMGLGMIKAIEQF-CQEKKE-MVNMRVGVHTGTVLCGILGMRRFKFDVWSN 512

  Fly  1076 TVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVT-------TYWLNSTS 1133
            .||.|:.||..|..||:|:|.||...||  ..::||....:|..|:..|.       ||.::...
Human   513 DVNLANLMEQLGVAGKVHISEATAKYLD--DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQR 575

  Fly  1134 EGEAR 1138
            ..|:|
Human   576 AKESR 580

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3216NP_726013.2 PBP1_NPR_like 90..496 CDD:107368
ANF_receptor 107..479 CDD:279440
PKc_like 616..885 CDD:304357
TyrKc 627..877 CDD:197581
HNOBA <882..939 CDD:285003 7/24 (29%)
CYCc 918..1109 CDD:214485 70/223 (31%)
Guanylate_cyc 945..1131 CDD:278633 67/195 (34%)
ADCY9XP_005255136.1 DUF2339 <118..>301 CDD:287113
CYCc 326..544 CDD:214485 70/222 (32%)
Guanylate_cyc 385..573 CDD:278633 66/192 (34%)
CYCc 1043..1243 CDD:214485
Guanylate_cyc 1069..1260 CDD:278633
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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