Protein Alignment CG3216 and Adcy3

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: NP_612178.2
• Gene: Adcy3 / 104111
• MGIID: 99675
• Length: 1145
• Species: Mus musculus
• Alignment Length: 590
• Identity: 134/590 - (22%)
• Similarity: 234/590 - (39%)
• Gaps: 198/590 - (33%)

  Fly   666 SHENTVRFVGACIDLPR------------------------PTVLILTEY--------------- 691
            :||.:||..|:|:.|||                        .|:|:|..:
Mouse    35 THEISVRNSGSCLCLPRFMRLTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVV 99

  Fly   692 -------------------------CSRGSLKDVLENEAIE-LDWNFRMSLIHDIVKGMNYLHNS 730
                                     |.:|.|.|.:..:.:. |.|....:.|...: |:|:..
Mouse   100 FSSDKLAPLMVAGFGLVLDIILFVLCKKGLLPDRVSRKVVPYLLWLLISAQIFSYL-GLNFSR-- 161

  Fly   731 DVAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCP 795
               ||                           ..||.|..|.:::...:|.   |||:..|
Mouse   162 ---AH---------------------------AASDTVGWQAFFVFSFFIT---LPLSLSP---- 189

  Fly   796 ATQRGDVYSFGIILEEIVNRGGPYQEARQQMDVHTILHKVRQCNGFRPLIRERECPPDLLELMEK 860
                       |::..:|:           ..|||::..|        .:.:::  .|.||.|
Mouse   190 -----------IVIISVVS-----------CVVHTLVLGV--------TVAQQQ--QDELEGM-- 220

  Fly   861 CWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEE 925
                 |..|...:.:...:..|:.|.....|.|..:| :.:....:||  |....|..:.|:.|.
Mouse   221 -----QLLREILANVFLYLCAIIVGIMSYYMADRKHR-KAFLEARQSL--EVKMNLEEQSQQQEN 277

  Fly   926 LLYQILPRPVAQQLMAGDLVEPE------EFS--------SVTIYFSDIVGFTELCARSSPMDVV 976
            |:..|||:.||.:::. |:.:.|      :|:        :|:|.|:||||||:|.:..|..::|
Mouse   278 LMLSILPKHVADEMLK-DMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELV 341

  Fly   977 NFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRAVSSFNLRH 1041
            ..||:|::.||::...|...:::.:||.|..:.|||:...| ||....||.|.::.|:|  .:|.
Mouse   342 KLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYRED-HAVCSILMGLAMVEAIS--YVRE 403

  Fly  1042 KPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFG 1106
            |.:..:.:|:|:|:|:|..||:|:|...|.::...|..|::||:.|.||::|:|.:|...|.  |
Mouse   404 KTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLK--G 466

  Fly  1107 TFQMEQRGD-------VELKGKGTVTTY---------------WLNST-----SEGEARPPTPQI 1144
            .|.:|. ||       ::.||   :.||               .||.:     :...::|.:|.:
Mouse   467 EFDVEP-GDGGSRCDYLDEKG---IETYLIIASKPEVKKTAQNGLNGSAVPNGAPASSKPSSPAL 527

  Fly  1145 LTTDE 1149
            :.|.|
Mouse   528 IETKE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357	45/283 (16%)
		TyrKc	627..877	CDD:197581	44/275 (16%)
		HNOBA	<882..939	CDD:285003	17/56 (30%)
		CYCc	918..1109	CDD:214485	67/204 (33%)
		Guanylate_cyc	945..1131	CDD:278633	67/221 (30%)
Adcy3	NP_612178.2	AC_N	<44..303	CDD:318454	59/341 (17%)
		Guanylate_cyc	310..494	CDD:306677	64/192 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	504..564		6/29 (21%)
		Guanylate_cyc	915..1122	CDD:306677

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810