DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3216 and LOC101732945

DIOPT Version :9

Sequence 1:	NP_726013.2	Gene:	CG3216 / 37376	FlyBaseID:	FBgn0034568	Length:	1161	Species:	Drosophila melanogaster
Sequence 2:	XP_031761012.1	Gene:	LOC101732945 / 101732945	-ID:	-	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	519	Identity:	231/519 - (44%)
Similarity:	319/519 - (61%)	Gaps:	34/519 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   636 GERVAIKKVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGSLKDV 700
            |..|||||:..|...|:..:..|:||.||:.|.|..:|:|.||::  |.|.::||||.:|||.||
Frog   213 GRIVAIKKIQKKTFTLSKTIRREVKQIRDLDHPNLCKFIGGCIEV--PNVALITEYCPKGSLNDV 275

  Fly   701 LENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPS 765
            |.:|.|.|:|.||.|..:||.:||.|||...: .|.:|:|.||:||.|:|.||:|:||.|...
Frog   276 LLSEDIPLNWGFRFSFAYDIAQGMAYLHQHRM-YHYRLKSTNCVIDDRWVCKITDYGLYTYRK-- 337

  Fly   766 DFVRDQNYY---LKLLWIAPELLPLTTIPGCCP-ATQRGDVYSFGIILEEIVNRGGPYQEARQQM 826
               .|.|.|   |..:::.||   ..|:.|  | .:...|:||:.|||.||..|..|..:.....
Frog   338 ---ADTNVYQERLVQVYMPPE---DETVSG--PEKSAAADMYSYAIILLEIATRNDPVPKDESGS 394

  Fly   827 DVHTILH-----KVRQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIRTIMKGF 886
            ..|..|.     |.:..||.       .||.:.:||:.:|.:.|..:||||..::..:.. |...
Frog   395 AEHCCLPLPELIKGKSDNGC-------PCPSEYVELIRRCRSQNPVQRPTFEQVKKQLYK-MNPH 451

  Fly   887 CENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFS 951
            ..:.:|.::..||:|:.:||.||.|:|:.|..|||:|:.|||.:||:.||..|..|...:.:.::
Frog   452 KVSPVDLMMTLMEKYSKHLEQLVAERTQDLMHEKQKTDRLLYSMLPKQVADDLRQGKPSQAQSYA 516

  Fly   952 SVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNG 1016
            |.||:||||||||.|.:.|:|..||:|||.||:|||.||..|||||||||||||:||||:|:.||
Frog   517 SATIFFSDIVGFTHLSSSSTPYQVVDFLNKLYTTFDDIIDNYDVYKVETIGDAYMVVSGVPKENG 581

  Fly  1017 DKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTAS 1081
            .:|..|||.||||::....:|.:.|||..:::||.|:|||||.|||||.|||.||||||||||||
Frog   582 IRHVSEIASMALDLVSVCKTFRIPHKPNTQLKIRAGIHSGSVVAGVVGTKMPRYCLFGDTVNTAS 646

  Fly  1082 RMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWLNSTSEGEARPPTPQIL 1145
            |||||.:..||..||:|..:|.:.|.:.:..||.:::||||.:|||||    ||:...|...::
Frog   647 RMESTSEALKIQCSSSTHDLLKQIGGYILVCRGTLQVKGKGDMTTYWL----EGKKNTPRKNVI 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357	95/257 (37%)
		TyrKc	627..877	CDD:197581	94/249 (38%)
		HNOBA	<882..939	CDD:285003	23/56 (41%)
		CYCc	918..1109	CDD:214485	111/190 (58%)
		Guanylate_cyc	945..1131	CDD:278633	109/185 (59%)
LOC101732945	XP_031761012.1	PKc_like	212..448	CDD:419665	94/255 (37%)
		HNOBA	<448..504	CDD:400168	23/55 (42%)
		CYCc	484..674	CDD:214485	111/189 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010