DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3216 and LOC101732477

DIOPT Version :9

Sequence 1:	NP_726013.2	Gene:	CG3216 / 37376	FlyBaseID:	FBgn0034568	Length:	1161	Species:	Drosophila melanogaster
Sequence 2:	XP_031757190.1	Gene:	LOC101732477 / 101732477	-ID:	-	Length:	690	Species:	Xenopus tropicalis

Alignment Length:	716	Identity:	261/716 - (36%)
Similarity:	360/716 - (50%)	Gaps:	135/716 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 GKFSVVAHYSGVH----------KVYSAVHGKKIHWPGGREEP----PPDVPPCGFLGNSTDCVG 533
            |..|::||....|          .:.|.|.|..|..|   ||.    |.|..||....:....:
Frog    46 GVTSLIAHIKVGHFQAALEAKSTVISSTVCGDGICSP---EENCALCPADCGPCPMPSSIKIAI- 106

  Fly   534 NFSTIMYSVFGLLLFLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEMGGMFGSKGGLQRL 598
                    |..|.||.....|.:...|.|.:  |.|.:.||.:...|:   .||.|
Frog   107 --------VLPLALFCSGFILALVWFQYQKQ--KMLWDESWILTVKDL---PGGTF--------- 149

  Fly   599 DVENISLQQFGIHSGRASIASF----TSLP---PQVYTT--------------IGQFKGERVAIK 642
                        |.|..|..|.    .|.|   |:::..              .|.:.|..||:|
Frog   150 ------------HCGLGSTISLKCNQNSQPGHRPEMFANTVFICGSSTDNFMQTGIYDGRIVAVK 202

  Fly   643 KVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIE 707
            ::..|...::..:..|::..|.:.|.|..:|:|..::   ..:.|:||||.:|||.|||.|:.|.
Frog   203 RIYKKNFTISKTVRKEVQHVRKLDHPNICKFIGGSVE---GNIFIITEYCPKGSLADVLFNDDIP 264

  Fly   708 LDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQ- 771
            |:|.||:|...||.:||.|||...: .||:|.|.||:||.|:|.||||:||..      :.||:
Frog   265 LNWGFRLSFATDIARGMAYLHQHKI-YHGRLTSRNCIIDDRWVCKISDYGLMV------YRRDEF 322

  Fly   772 ---------NYYL-------KLLWIAPELLPLTTIPGCCPATQRGDVYSFGIILEEIVNRGGPYQ 820
                     |.|.       ...|:.|              |...||||:.|||.||.:|..|:.
Frog   323 KEIMEKKPANIYCPPEVMNSDSKWVMP--------------TASADVYSYAIILVEIASRCDPFP 373

  Fly   821 EARQQMDVHTILHKVRQCNGFRPLI-------RERECP--PDLLELMEKCWADNQEERPTFSTIR 876
            .|....|.           .:||.|       .:.:||  .|..||::||||.|...||:|..||
Frog   374 GAIYMKDA-----------SWRPRIPDLSAGKADHDCPNQADYSELVKKCWAHNPLLRPSFEHIR 427

  Fly   877 SNIRTIMKGFCENLMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMA 941
            ..:.. |.....:.:|.::|.||:|:.:||::|.|:|:.|..|||:|:.|||.:||:|||..|..
Frog   428 KTLER-MNPHKVSPVDMMMNLMEKYSKHLEAVVAERTQDLLQEKQKTDRLLYSMLPKPVADDLRQ 491

  Fly   942 GDLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYL 1006
            |.:.|.:.:::.|::||||||||.:.:.|:|..||:|||.||:.||.||..|||||||||||||:
Frog   492 GLMCEAQSYANATVFFSDIVGFTSISSASTPYQVVDFLNKLYTIFDDIIDNYDVYKVETIGDAYM 556

  Fly  1007 VVSGLPEPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYC 1071
            ||||:|:.||.||..|||.||||::....||.:.|.|:..:|||.|:|||.|.:||||.|||.||
Frog   557 VVSGVPKENGIKHVAEIASMALDLVSVCHSFKIPHIPDRNLQIRAGIHSGPVVSGVVGTKMPRYC 621

  Fly  1072 LFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWLNSTSEGE 1136
            |||||||||||||||.:..||..||:...:|.|.|.:.:..||.:.:||||.:||:||......:
Frog   622 LFGDTVNTASRMESTSEALKIQCSSSAAELLQKIGGYILTCRGALNVKGKGEMTTWWLEEKETQK 686

  Fly  1137 A 1137
            |
Frog   687 A 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368	5/22 (23%)
		ANF_receptor	107..479	CDD:279440
		PKc_like	616..885	CDD:304357	97/315 (31%)
		TyrKc	627..877	CDD:197581	90/289 (31%)
		HNOBA	<882..939	CDD:285003	24/56 (43%)
		CYCc	918..1109	CDD:214485	109/190 (57%)
		Guanylate_cyc	945..1131	CDD:278633	105/185 (57%)
LOC101732477	XP_031757190.1	PKc_like	182..433	CDD:419665	91/286 (32%)
		HNOBA	<433..489	CDD:400168	24/55 (44%)
		CYCc	469..659	CDD:214485	109/189 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010