Protein Alignment CG3216 and gucy2f

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: XP_002931862.2
• Gene: gucy2f / 100492820
• XenbaseID: XB-GENE-480268
• Length: 1112
• Species: Xenopus tropicalis
• Alignment Length: 1164
• Identity: 376/1164 - (32%)
• Similarity: 589/1164 - (50%)
• Gaps: 148/1164 - (12%)

  Fly    56 GLEQRMYERSRESKSTQLSRY-TEVGEMGSTMRV-----------YNVGVLMASHLDSPFDLERC 108
            ||:...|.:..||.....|.: :::..:||.:.:           |.|||:.....|..|.....
 Frog    12 GLKCTSYPKWTESDYLLFSTFPSKIILLGSLLAILCFPQFVHCIPYKVGVVGPWSCDPLFSKALP 76

  Fly   109 GPAVDLALDEINK-----VFLKPHNITLLKKKGSYPSCSGARAPGLAADMYFQDDVIAFIGPACA 168
            ..|..||::.|||     :.|. .|..:|::     .|..::|  |:..:.:......||||:..
 Frog    77 NVAAKLAIERINKDASLDLGLS-FNYVILEE-----DCQTSKA--LSTFLTYSGVASGFIGPSNP 133

  Fly   169 FALEPVARLAAYWNKPIITGMGDQPPSSEGELTVTSGILGRIHKWKNENTGMFKDKSKYPTLTRM 233
            ...:....|...|||.:.:                         |...|..:...|| |||..|.
 Frog   134 GYCDAATLLGKNWNKAVFS-------------------------WACINYELDNVKS-YPTFART 172

  Fly   234 SYCQCRLILVFASVIRQFNWNHVALLVDRSELFSWTVGKNLEYGLRQEGLLSFVKELNGNE---- 294
            .....|::.   :|::.|.|.||.::....:::..| |:.:...||..||...:....|::
 Frog   173 LPSPTRVLF---NVMKYFQWAHVGVISSNEDIWRDT-GRKVANALRSNGLPVGIVVSMGDDIRST 233

  Fly   295 EEVYENYLKDASMYARVVILSVRGVLV-----RKFMLAAHSLGMTNGEWVFLDVE-IFQSEYWGD 353
            ::..|...|..::  |::|:.:..||:     ::.:..||.|.||:|.:||:..: ::.|..:..
 Frog   234 QQALEKVRKIDNI--RMIIMCMHSVLIGGQAQQRLLEVAHDLKMTDGTYVFVPYDTLYYSLPYHK 296

  Fly   354 KGWEM-KDEHDAKARKAYEALLRVSLLQPTSPKFQDFADNVRENALYDYNYTFGEGEEVNFFIGA 417
            ..::| |:..:..|  ||:::|.:: ::.....|.:.....:|:...:.|.   :..:|:...|.
 Frog   297 TTYDMLKNSPNLTA--AYDSVLTIT-VESEGKTFYEAFQEAQESGEMNANI---KPSQVSPLFGT 355

  Fly   418 FYDGVYLLGMALNETLTEGGDIRDGVNITRRMWNRTFEGITGHVRIDDNGDRDADYSILDLDPIN 482
            .|:.:|....|:|.:..:|..: .|.::.:...|..|.|....::.|.:|:...||.|||.|...
 Frog   356 IYNAIYFTAYAMNSSRRQGTWV-SGSSLVKHSKNMQFYGFNQWIKTDMSGNGFTDYVILDADMKT 419

  Fly   483 GKFSVVAHYSGVHKVYSA--------VHGKKIHWPGGREEPPPDVPPCGFLGNSTDCVGNFSTIM 539
            .:         :|:.|..        ..|:.||:|.| ..|..| ..|.| .:...|.|...
 Frog   420 NE---------LHRTYVVDMETDMVRYMGRPIHFPNG-VSPKTD-SYCWF-SDGKICTGGIE--- 469

  Fly   540 YSVFGLLLFLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEM-----------------GG 587
             ..|.|::||.:|..:|.|......:.:.:|.:.....|:.:|:.:                 .|
 Frog   470 -PAFALMVFLCIVVAIISLNGLAYVIRRRINKIKLVRGPNKILLTLEDVTFINPQLSVKKLSNDG 533

  Fly   588 MFGSKGGLQRLDVENISLQQFGIHSGRASIASFTSLPPQVY--TTIGQFKGERVAIKKVNVKKV- 649
            ...|..|....|..::   :..:.||     |..||.|..|  :.:..::|:.|.:||......
 Frog   534 SRTSDSGPVLTDTRSM---KSPMRSG-----STQSLIPATYENSNVAIYEGDWVWMKKFPSGDFG 590

  Fly   650 DLTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIELDWNFRM 714
            :|.|......:..:|:.|||...|:|...|.  ....|:||:||||||:|:|.|:.::|||.|:.
 Frog   591 ELKPGTSDVFETMKDMRHENVNPFLGFFHDC--GVFAIVTEFCSRGSLEDLLRNQDVKLDWMFKS 653

  Fly   715 SLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQNYYLKLLW 779
            ||:.|::|||.|||:... .||:|:|.||::|||||||::|:|...:........::....:|||
 Frog   654 SLLLDLIKGMKYLHHRKF-VHGRLKSRNCVVDGRFVLKVTDYGYNEVLEAQRIPHEEPTAYELLW 717

  Fly   780 IAPELL--PLTTIPGCCPATQRGDVYSFGIILEEIVNRGGPYQEARQQMDVHTILHKVRQ----C 838
            .|||||  ||:.:.|    :..||||||.:|::|:|.||.|:.......:  .|:.||::    |
 Frog   718 TAPELLRDPLSAVHG----SFSGDVYSFSVIMQEVVVRGPPFCTVEDTAE--EIIQKVKKPPPLC 776

  Fly   839 NGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIRTIMKGFCENLMDDLLNRMEQYAN 903
               ||::.....|.:.:.||:|||.:..:.||:|..|....:.|.||...|::|.:|..:|||::
 Frog   777 ---RPMVSPDHAPMECIILMKKCWNEVPDRRPSFDEIFDQFKNINKGRKTNIIDSMLRMLEQYSS 838

  Fly   904 NLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCA 968
            |||.|:.|:|.:|.:|||:||:||.|:||..||:.|..|..||||.|..||:|||||||||.:.|
 Frog   839 NLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAEALKMGCTVEPEGFDEVTLYFSDIVGFTSISA 903

  Fly   969 RSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRA 1033
            .|.|::||:.|||||:.||.:||.:||||||||||||:|.||||:.||::||.|||.|:||||.:
 Frog   904 MSEPIEVVDLLNDLYTLFDAVIGNHDVYKVETIGDAYMVASGLPKRNGNRHAAEIANMSLDILSS 968

  Fly  1034 VSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSAT 1098
            |.||.:||.|:..::||||:|||...|||||..||.||||||||||||||||||.|.:|||:.:|
 Frog   969 VGSFKMRHMPDVPVRIRIGLHSGPAVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNQST 1033

  Fly  1099 KAILDKFGT-FQMEQRGDVELKGKGTVTTYWLNSTSEGEARP-PTPQILTTDEVPFPLL 1155
            ...|..... :.:|.||..||||||...|:||.. .||..:| |.|.::.:.::...||
 Frog  1034 VKTLRSLNEGYLLELRGRTELKGKGIEETFWLVG-KEGFTKPLPVPPVIKSGQMGHGLL 1091

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368	89/421 (21%)
		ANF_receptor	107..479	CDD:279440	83/387 (21%)
		PKc_like	616..885	CDD:304357	98/277 (35%)
		TyrKc	627..877	CDD:197581	93/258 (36%)
		HNOBA	<882..939	CDD:285003	28/56 (50%)
		CYCc	918..1109	CDD:214485	117/191 (61%)
		Guanylate_cyc	945..1131	CDD:278633	115/186 (62%)
gucy2f	XP_002931862.2	PBP1_sensory_GC_DEF-like	58..439	CDD:380594	91/436 (21%)
		PK_GC-2D	553..820	CDD:270945	100/283 (35%)
		HNOBA	<829..874	CDD:400168	23/44 (52%)
		CYCc	853..1044	CDD:214485	117/190 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010