Protein Alignment CG3216 and adcy1

DIOPT Version :9

• Sequence 1: NP_726013.2
• Gene: CG3216 / 37376
• FlyBaseID: FBgn0034568
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: XP_002933461.1
• Gene: adcy1 / 100492373
• XenbaseID: XB-GENE-950909
• Length: 1122
• Species: Xenopus tropicalis
• Alignment Length: 1132
• Identity: 222/1132 - (19%)
• Similarity: 380/1132 - (33%)
• Gaps: 405/1132 - (35%)

  Fly   288 KELNGNEEEVYENY-LK---DASMYARVVILSVRGVLVRKFMLAAHSLGMTNGEW-----VFLDV 343
            |||    |.:::|| ||   .:::.|..|::.:.|.|....:::..||.::.|..     :||.:
 Frog    41 KEL----ESLFQNYNLKLEQTSTLKALAVLIIMTGTLALLELMSGPSLTISKGSHPVHCIIFLSL 101

  Fly   344 EI--------------------------------FQSEYWG-------DKG-WEMKDEHDAKARK 368
            .|                                |....:|       ::| |::.    .....
 Frog   102 FIVTNVKYLQVTQLQQIVKLTLLFGFTFSFLCCPFSLGAYGLEPPVSSEQGLWQLM----LVTFV 162

  Fly   369 AYEALLRVSLL------------------QPTSPKFQDFADNVRENALYDYNYTFGEGEEVNFFI 415
            || |||.|..|                  ...|||.:.....:..||:              .|:
 Frog   163 AY-ALLPVRTLLAIVFGFMVSVSHIIVTATSISPKKKRLWRTLVVNAI--------------LFV 212

  Fly   416 GAFYDGVYLLGMALNETLTEGGDIRDGVNITRRMWNRTFEGITGHVRIDDNGDRDADYSILDLDP 480
            .....||::      ..|||        ...|:.:.:....|...:|::|..::. :..::.|.|
 Frog   213 SVNLSGVFV------RILTE--------RAQRKAFLQARNCIEDRLRLEDENEKQ-ERLLMSLLP 262

  Fly   481 INGKFSVVAHYSG-----VHKVYSAVHGKKIHWPGGREEPPPDVPPCGFLGNSTDCVGNFSTIMY 540
            .|....:...:..     .||:|...|                              .|.|.:..
 Frog   263 RNVAMEMKEDFLKPPERIFHKIYIQRH------------------------------DNVSILFA 297

  Fly   541 SVFGLLLFLGLVFLVICLLQKQMKLSKEL---------NNMSWRVR-PDDVLIEMGGMFGSKG-- 593
            .:.|   |..|...  |..|:.:||..||         .|...|:: ..|....:.|:...|.
 Frog   298 DIVG---FTSLASQ--CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDH 357

  Fly   594 -------GLQRLD-------VENISL-QQFGIHSGR----------------------ASIASFT 621
                   ||..:|       ...:.| .:.|:|:||                      |::....
 Frog   358 AHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAG 422

  Fly   622 SLPPQVYTT-------IGQFKGE-------RVAIKKVNVKKVDLTPQ---------LLWEIKQAR 663
            .||.:|:.|       .|.::.|       ...:||.|::...:.|.         :|.:||.|:
 Frog   423 GLPGKVHITKNTLECLNGDYEVEPGYGHERNSFLKKHNIETFFIVPSHRRKIFPGLILSDIKPAK 487

  Fly   664 DVSHENTVRFVGAC--------------IDLPRPTVLILTEYCSRGSLK---DVLENEAIELDWN 711
                  .::|...|              .::|...|:...:...|.:|:   :.|.|.:     :
 Frog   488 ------RMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRS-----S 541

  Fly   712 FRMSLIHDI--VKGMNYLHNSDVAAHGKLRSCNCLIDGRFV-LKISDFGLRTLTTPSDFVRDQNY 773
            |..::||:.  .:...|:        |:      ||:.|.. .::||....||.. ....|:|.|
 Frog   542 FSTNVIHNTPGTRVNRYI--------GR------LIEARQTDSEMSDLNFITLKY-KHIEREQKY 591

  Fly   774 Y----------------------LKLLWIAPE--------------------LLPLTTI---PGC 793
            :                      |..|.|.|:                    .|.:|.:   |||
 Frog   592 HQLHDEYFTSAVVLSLILAALFGLVYLLIFPQSTIVLILLVFCLCFLVACIMYLHVTRVQCFPGC 656

  Fly   794 CPATQRGDVYSFGIILEEIVNRG-----GPY-QEARQQMDVHTILHKVRQCNGFRPLIRERECP- 851
            .....|..:..|.:||...|.:|     .|: ..:.....:..|..|     |....:.||.|.
 Frog   657 LTIQIRTILCIFIVILIYSVAQGCVVGCMPWIWRSNNSSSIVIITPK-----GENKTMNERPCDT 716

  Fly   852 ------------------------PDLLELMEKCWADNQEERPTFSTIRSNIRTIMKGFCENLMD 892
                                    |.::.|:             |.||...:...:.|:.:.|..
 Frog   717 AHYTFLSCVVGTLSLAIFLRISSFPKMVLLL-------------FVTILYIVILEISGYRKTLGG 768

  Fly   893 D---------------------LLNRMEQYANNLESL----VEEKTRQLSLEKQRTEELLYQILP 932
            |                     |.:|.......|:.|    .||:...:...|...:.:|:.:||
 Frog   769 DTSYMRGYEPILAILLFSCSLALHSRQVDLKLRLDYLWAVQAEEERDDMERVKLDNKRILFNLLP 833

  Fly   933 RPVAQQLMAG-----DLVEPEEFSSVTIYFSDIVGFT----ELCARSSPMDVVNFLNDLYSTFDR 988
            ..|||..:..     ||.. :.:|.|.:.|:.|..|.    ||...:..::.:..||::.:.||.
 Frog   834 AHVAQHFLMSNPRNMDLYY-QSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDE 897

  Fly   989 IIG---FYDVYKVETIGDAYLVVSGLPEPNGDK-------HAREIALMALDILRAVSSFNLRHKP 1043
            ::.   :.|:.|::|||..|:...||....|.|       |...:|..::::...:...|.:...
 Frog   898 LMEKECYKDIEKIKTIGSTYMGAVGLVPTTGTKAKKSIYSHLSTLADFSIEMFDVLDEINYQSYN 962

  Fly  1044 EYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTF 1108
            |:  .:|:|::.|.|.|||:|.:.|.|.::|:|||.||||:|||..|||.|:.....|| |...:
 Frog   963 EF--VLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTEDVHRIL-KSCNY 1024

  Fly  1109 QMEQRGDVELKGKGTVTTYWLNSTSEG 1135
            :...||.|.:||||.:.||:|....:|
 Frog  1025 EFVCRGKVSVKGKGEMLTYFLEGKIDG 1051

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3216	NP_726013.2	PBP1_NPR_like	90..496	CDD:107368	47/279 (17%)
		ANF_receptor	107..479	CDD:279440	44/257 (17%)
		PKc_like	616..885	CDD:304357	64/387 (17%)
		TyrKc	627..877	CDD:197581	62/368 (17%)
		HNOBA	<882..939	CDD:285003	16/81 (20%)
		CYCc	918..1109	CDD:214485	62/209 (30%)
		Guanylate_cyc	945..1131	CDD:278633	63/199 (32%)
adcy1	XP_002933461.1	AC_N	<37..282	CDD:292831	47/278 (17%)
		CYCc	248..443	CDD:214485	38/230 (17%)
		Guanylate_cyc	284..466	CDD:278633	36/216 (17%)
		CYCc	817..1028	CDD:214485	62/214 (29%)
		Guanylate_cyc	850..1047	CDD:278633	64/200 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910