| Sequence 1: | NP_004965.1 | Gene: | KCNA2 / 3737 | HGNCID: | 6220 | Length: | 499 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001097131.2 | Gene: | Shawl / 5740840 | FlyBaseID: | FBgn0085395 | Length: | 937 | Species: | Drosophila melanogaster |
| Alignment Length: | 510 | Identity: | 168/510 - (32%) |
|---|---|---|---|
| Similarity: | 245/510 - (48%) | Gaps: | 139/510 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Human 34 RVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL 98
Human 99 RRPVNVPLDIFSEEIRFYELGEEAME--------MFREDEGYIK-------EEERPLPE------ 142
Human 143 -----------NEFQR---QVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDE-- 191
Human 192 --NEDMHGSGV-----------------TFHTYS----NSTIG---------YQQSTSFT----- 219
Human 220 --------------------------------------------------DPFFIVETLCIIWFS 234
Human 235 FEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLV 299
Human 300 RVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE--ADERESQFPSIP 362
Human 363 DAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 417 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNA2 | NP_004965.1 | Tetramerization domain. /evidence=ECO:0000250|UniProtKB:P63142 | 1..125 | 36/98 (37%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..26 | ||||
| BTB_POZ | 33..159 | CDD:365784 | 47/159 (30%) | ||
| Ion_trans | 162..420 | CDD:395416 | 119/347 (34%) | ||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 312..325 | 7/12 (58%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 374..379 | 4/4 (100%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:P63142 | 497..499 | ||||
| Shawl | NP_001097131.2 | BTB | 7..99 | CDD:197585 | 35/92 (38%) |
| BTB_2 | 7..97 | CDD:280393 | 35/90 (39%) | ||
| Ion_trans | 307..506 | CDD:278921 | 93/208 (45%) | ||
| Ion_trans_2 | <449..499 | CDD:285168 | 36/49 (73%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||