| Sequence 1: | NP_004965.1 | Gene: | KCNA2 / 3737 | HGNCID: | 6220 | Length: | 499 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001189037.1 | Gene: | Shab / 38352 | FlyBaseID: | FBgn0262593 | Length: | 1607 | Species: | Drosophila melanogaster |
| Alignment Length: | 481 | Identity: | 173/481 - (35%) |
|---|---|---|---|
| Similarity: | 259/481 - (53%) | Gaps: | 90/481 - (18%) |
- Green bases have known domain annotations that are detailed below.
|
Human 34 RVVINISGLRFETQLKTLAQFPETLLGDPKKRMRY-------------FDPLRNEYFFDRNRPSF 85
Human 86 DAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAM-----------------EMFREDEGYI 133
Human 134 KEEERPLPEN---EFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDM 195
Human 196 HGSGVTFHTYSNSTIGYQQSTSFTDP-FFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIID 259
Human 260 IVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKAS 324
Human 325 MRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKI 389
Human 390 VGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTIS 454
Human 455 KSDYMEIQEGVNNSNEDFREENLKTA 480 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNA2 | NP_004965.1 | Tetramerization domain. /evidence=ECO:0000250|UniProtKB:P63142 | 1..125 | 32/120 (27%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..26 | ||||
| BTB_POZ | 33..159 | CDD:365784 | 44/157 (28%) | ||
| Ion_trans | 162..420 | CDD:395416 | 115/258 (45%) | ||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 312..325 | 7/12 (58%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 374..379 | 4/4 (100%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:P63142 | 497..499 | ||||
| Shab | NP_001189037.1 | BTB | 309..416 | CDD:197585 | 31/111 (28%) |
| BTB_2 | 309..408 | CDD:280393 | 31/103 (30%) | ||
| Ion_trans | 501..700 | CDD:278921 | 103/201 (51%) | ||
| Ion_trans_2 | 613..696 | CDD:285168 | 49/82 (60%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||