| Sequence 1: | NP_004965.1 | Gene: | KCNA2 / 3737 | HGNCID: | 6220 | Length: | 499 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001303569.1 | Gene: | Sh / 32780 | FlyBaseID: | FBgn0003380 | Length: | 655 | Species: | Drosophila melanogaster |
| Alignment Length: | 467 | Identity: | 319/467 - (68%) |
|---|---|---|---|
| Similarity: | 371/467 - (79%) | Gaps: | 24/467 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Human 17 GHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRN 81
Human 82 RPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQ 146
Human 147 RQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNST-I 210
Human 211 GYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELA 275
Human 276 EK------------PEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMREL 328
Human 329 GLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSL 393
Human 394 CAIAGVLTIALPVPVIVSNFNYFYHRETEGEE-QAQ-YLQVTSCPKIPSSPDLKKSRSASTISKS 456
Human 457 DYMEIQEGVNNS 468 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNA2 | NP_004965.1 | Tetramerization domain. /evidence=ECO:0000250|UniProtKB:P63142 | 1..125 | 84/107 (79%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..26 | 3/8 (38%) | |||
| BTB_POZ | 33..159 | CDD:365784 | 106/125 (85%) | ||
| Ion_trans | 162..420 | CDD:395416 | 185/270 (69%) | ||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 312..325 | 11/12 (92%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 374..379 | 4/4 (100%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:P63142 | 497..499 | ||||
| Sh | NP_001303569.1 | BTB_2 | 99..187 | CDD:280393 | 75/87 (86%) |
| BTB | 99..182 | CDD:197585 | 72/82 (88%) | ||
| Ion_trans | 274..488 | CDD:278921 | 160/214 (75%) | ||
| Ion_trans_2 | 403..479 | CDD:285168 | 61/75 (81%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 362 | 1.000 | Domainoid score | I953 |
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 620 | 1.000 | Inparanoid score | I885 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG48093 | |
| OrthoDB | 1 | 1.010 | - | - | D307298at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000074 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42203 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101149 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11537 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3654 |
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.910 | |||||