DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Act57B and Actr2

DIOPT Version :9

Sequence 1:	NP_523800.1	Gene:	Act57B / 37368	FlyBaseID:	FBgn0000044	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_017454617.1	Gene:	Actr2 / 289820	RGDID:	1310826	Length:	399	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	175/385 - (45%)
Similarity:	253/385 - (65%)	Gaps:	20/385 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRP------RHQGVMVGMGQK-DSYVGDEAQSKRGIL 66
            :|.|||:|..|.|:||.:.|..:||::||||      :...:.:...:| |..|||||...|.:|
  Rat     9 VVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDEASELRSML 73

  Fly    67 TLKYPIEHGIITNWDDMEKIWHHTFYNE-LRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNS 130
            .:.||:|:||:.|||||:.:|.:||..| |.:......:||||.|:||..||||:.::||||:..
  Rat    74 EVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRSCKILLTEPPMNPTKNREKIVEVMFETYQF 138

  Fly   131 PAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILT 195
            ..:||||||||:|||.|..||:|:||||||:|..|:|||::|||...|||:||||:|.||:|:|.
  Rat   139 SGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLL 203

  Fly   196 ERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPE 260
            .|||:|..:|:.|.||.||||||||..:.|||...|..:|.|.:||.||||::|.:|.|||..||
  Rat   204 LRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPE 268

  Fly   261 SLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITSL---- 321
            :||||..:.:|..|:.|.::|:|...|:|.|.:.|.:||:|||:|||||:..|:::|:..|
  Rat   269 ALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLER 333

  Fly   322 -------APSTIKIKIIAPPERKYSVWIGGSILAS-LSTFQQMWISKEEYDESGPGIVHR 373
                   ..|..||:|..||.||:.|::||::||. :......|::::||.|.|..::.:
  Rat   334 VLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEK 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act57B	NP_523800.1	PTZ00281	1..376	CDD:173506	175/385 (45%)
Actr2	XP_017454617.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820