DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rx and Isx

DIOPT Version :9

Sequence 1:	NP_726006.3	Gene:	Rx / 37367	FlyBaseID:	FBgn0020617	Length:	904	Species:	Drosophila melanogaster
Sequence 2:	XP_008770554.1	Gene:	Isx / 682968	RGDID:	1592776	Length:	242	Species:	Rattus norvegicus

Alignment Length:	226	Identity:	80/226 - (35%)
Similarity:	104/226 - (46%)	Gaps:	71/226 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   509 ERLNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHE 573
            ||.|......:.|.     |..||.:|  |.|:...:.|:.|::   :|..||.||||||.||.|
  Rat    38 ERRNLPRPQSIGGG-----DSRQTTTS--GSKLEKPTQDQPQEE---RKNKRRVRTTFTTEQLQE 92

  Fly   574 LERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKSESL--------------- 623
            ||:.|..:||||::.|.:||.::||||.|||:||||:|||||:||||.||
  Rat    93 LEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEKSGSLSAPQQPGSCTDAHCS 157

  Fly   624 -RLGLTH-----------FTQLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTPP 676
             .:|.||           |..:|    |..|..|:.| :.|    |.|.:.|||..:.| ||.||
  Rat   158 AHIGATHRMLPPLSDSARFKLVP----CPDSPCPMAP-MGP----AAPAWPSHPAALCP-YLHPP 212

  Fly   677 LSLAPGNLTMSSLAAMGHHHAHNGPPPPHVG 707
                                    .|.|.||
  Rat   213 ------------------------TPKPQVG 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeobox	563..615	CDD:278475	33/51 (65%)
Rx	NP_726006.3	OAR	876..892	CDD:281777
Isx	XP_008770554.1	Homeobox	82..134	CDD:278475	33/51 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910