DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rx and alx1

DIOPT Version :9

Sequence 1:NP_726006.3 Gene:Rx / 37367 FlyBaseID:FBgn0020617 Length:904 Species:Drosophila melanogaster
Sequence 2:NP_001038539.1 Gene:alx1 / 565176 ZFINID:ZDB-GENE-050419-191 Length:320 Species:Danio rerio


Alignment Length:434 Identity:111/434 - (25%)
Similarity:157/434 - (36%) Gaps:168/434 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   478 QQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERLNADSDSLVNGSCAS------SEDLNQTNSSE 536
            |....|...||.  :....:|..|.:|..:....:.:|......:|.|      :...::|:..|
Zfish    44 QAFPMQSNDQHS--SMDRSSPCDNQSSVTYCAPKSEESSLHAMENCCSLRVSPATSGPDKTDLDE 106

  Fly   537 QGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEV 601
            .|||.         |.|.:..|.||:|||||:.||.|||:.|:|:||||||.||:|||:..|.|.
Zfish   107 LGEKC---------DSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEA 162

  Fly   602 RVQVWFQNRRAKWRRQEKSESLRLGLTHFTQLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQ 666
            ||||||||||||||::|:...::...:||.....                   :|.||...|:.|
Zfish   163 RVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYD-------------------ISMLPRTDSYSQ 208

  Fly   667 TVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGS 731
             :..:..|.|   :.|:..:||...                        |...||....|:||  
Zfish   209 -ISNNLWTGP---SAGSSVVSSCMI------------------------PRGSPPCVTSPYPH-- 243

  Fly   732 HHVVPLSHLSPHLSRMSPHATS---LGSPHHGVTPLGTPLHSSLPPSSTATTVAVSSSQSSSSSA 793
                            ||.|..   :|.|:|.....|.                           
Zfish   244 ----------------SPRAAEHGYVGFPNHQQNQFGV--------------------------- 265

  Fly   794 SLECSGPDVCMSPQNLSIGN--ADSNGDGRDLSSDLDAGSTSSNPGSSLDKCAASANIELLDVGR 856
                         .::|:.|  |||          |.|.|.:|:           |..|      
Zfish   266 -------------NHVSLNNFFADS----------LLASSANSH-----------AAFE------ 290

  Fly   857 DSPPPPPTPTGKGSSTPPTDMRSNSIATLRIKAKEHLDNLNKGM 900
                          :.|..:.||:|||.||:|||||..|::..|
Zfish   291 --------------TKPEFERRSSSIAVLRMKAKEHTANISWAM 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RxNP_726006.3 Homeobox 563..615 CDD:278475 37/51 (73%)
OAR 876..892 CDD:281777 10/15 (67%)
alx1NP_001038539.1 Homeobox 123..176 CDD:278475 37/52 (71%)
Transactivation domain. /evidence=ECO:0000250|UniProtKB:Q63087 180..320 50/285 (18%)
OAR 296..313 CDD:281777 11/16 (69%)
OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138 300..313 9/12 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D454642at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.920

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