Protein Alignment Rx and toe

DIOPT Version :10

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 743
• Identity: 172/743 - (23%)
• Similarity: 240/743 - (32%)
• Gaps: 278/743 - (37%)

  Fly   217 GALPYGPPT------PPGGQQPQVPNATPL-HHGQQMGGQAGHATHAGHGHPT------------ 262
            ||.|..|.|      .||...|..  |.|| .|.|.:|..||     |.|.|.
  Fly    22 GAAPAIPATATAGSQSPGAIMPMA--AVPLPSHLQLLGSSAG-----GVGQPAAITPVSPTAATT 79

  Fly   263 ----HHGHAPF------GYHNAFGFGQ---GGHGYGHPEEAAG-----NYLNSMHQMVEANQLQT 309
                .|..:|.      |...|...|.   ||.....|..||.     |.|.|.|:::|.::.
  Fly    80 VLAQPHSLSPSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRF-- 142

  Fly   310 GANGANPPPAPL--------------PPSSFGSHQQHLAALAAQAQEQQNQHSKYAKSSPTGAGP 360
            |..|.:.....|              ||...|..:..:|.....::.:|     |.:.:||
  Fly   143 GLRGYDLAQHMLSQQGAVSKLLGTLRPPGLIGGSKPKVATPTVVSKIEQ-----YKRENPT---- 198

  Fly   361 PPPPGAYFME------------SQTAPVAPSQINYDERSMSSASDLEEDDDDAA-KLQLDVTSP- 411
                 .:..|            :.||| :.|.||...|:.::.....|....|: ...:..|.|
  Fly   199 -----IFAWEIRERLITEGVCTNATAP-SVSSINRILRNRAAERAAAEFARAASYGYAIHPTHPH 257

  Fly   412 ------------------PTPSPRGQLAAKRKSAGVFCDDNEPKLANGQL-PGG---NYGIRPRS 454
                              |..:|.|               ..|..|.|.| |||   :||
  Fly   258 PYTSFPTWPAHHPLWGAVPLATPPG---------------GGPAGAGGALQPGGSGSSYG----- 302

  Fly   455 MEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGN--GNPNGNSNSGDHGERLNADSDS 517
                                                 :.||  .|||.::::..|....|.:|.|
  Fly   303 -------------------------------------SDGNMSSNPNSSNSNTTHSNGHNTNSGS 330

  Fly   518 LVNGSCASSEDLN-QTNSSEQGEKIT-------------SGSDDEGQDDNCAKKKHRRNRTTFTT 568
            ....|.|.|..|: ...|.:.|.:.:             .|.|.|.||.:  :.|.|||||||:.
  Fly   331 GCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSD--QPKFRRNRTTFSP 393

  Fly   569 YQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKSESLRLGLTHFTQL 633
            .||.|||:.|:|||||.|.:||:||.:..|.|.||||||.||||||||.:     |:.|......
  Fly   394 EQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQ-----RVNLIKQRDS 453

  Fly   634 PHRLGCGASGLP-VDPWLSPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHA 697
            |   ...:|..| |:|.:||  :|.:|
  Fly   454 P---STSSSPTPLVNPVVSP--VSPIP-------------------------------------- 475

  Fly   698 HNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHATSLGSPHH--- 759
              .|.|..|...|. |.||.|....:.......|.:..|.:.::|. |:||...:|:.|..|
  Fly   476 --VPVPVAVPESGQ-QKQPYPYSTSNMCNTSSSSSNSQPCNTINPG-SKMSSKTSSVSSNQHMEE 536

  Fly   760 -------------------------GVTPLGTPLHSSLPPSSTATTVAVSSSQSSSSSASLECSG 799
                                     ...|:..|:..:||.:|.|......:.|..:....
  Fly   537 PAAAVATASPTASAPLSMGGENSAFRALPMTLPMPMTLPTASAAAFALSFARQYIAKYMG----- 596

  Fly   800 PDVCMSPQNLSIGNADSNG-DGRDLSSD 826
                 :|.||..|::.... .|||..|:
  Fly   597 -----TPLNLGHGSSPIQAQSGRDHQSE 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	37/55 (67%)
		OAR	876..892	CDD:461067
toe	NP_524041.2	HTH_ARSR	134..230	CDD:481197	20/112 (18%)
		Homeodomain	385..441	CDD:459649	37/55 (67%)